RA CAPITAL MANAGEMENT, L.P. is an investment firm that reports beneficial ownership of shares in Vor Biopharma Inc. (VOR) and 27 other companies under U.S. securities law. It has submitted 85 SEC insider filings since 2024, most recently in August 2026.
Every role RA CAPITAL MANAGEMENT, L.P. has reported on a Form 4, reconstructed from the filings themselves. Reporting insiders must state their relationship to the issuer (officer title, director seat, or 10% ownership) on every filing.
Vor Biopharma Inc. (VOR)3 filingsSepterna, Inc. (SEPN)2 filingsArtiva Biotherapeutics, Inc. (ARTV)8 filingsInhibikase Therapeutics, Inc. (IKT)1 filingFreenome, Inc. (FRNM)1 filingParabilis Medicines, Inc. (PBLS)3 filingsClimb Bio, Inc. (CLYM)2 filingsARS Pharmaceuticals, Inc. (SPRY)1 filingWerewolf Therapeutics, Inc. (HOWL)3 filings
Acrivon Therapeutics, Inc. (ACRV)1 filing
PepGen Inc. (PEPG)1 filing
Sionna Therapeutics, Inc. (SION)1 filing
Hemab Therapeutics Holdings, Inc. (COAG)1 filing
LENZ Therapeutics, Inc. (LENZ)1 filing
Janux Therapeutics, Inc. (JANX)1 filing
Nkarta, Inc. (NKTX)1 filing
Bicara Therapeutics Inc. (BCAX)1 filing
Acumen Pharmaceuticals, Inc. (ABOS)1 filing
Tyra Biosciences, Inc. (TYRA)1 filingUpdated Aug 30, 2026
RA CAPITAL MANAGEMENT, L.P. is 10% Owner of Vor Biopharma Inc. (VOR). 84 SEC Form 4 filings on record going back to 2024, most recently on 26 August 2026. Most recent open-market trade: sold $31.73M of SEPN on 14 August 2026. Lifetime open-market purchases: $1.02B. Lifetime open-market sales: $169.01M. Historical track record: 5/5 stars across 40 tracked purchases.
Every recent SEC Form 4 transaction RA CAPITAL MANAGEMENT, L.P. has reported, most recent first.
InsiderAlpha computes a forward-return-based score for every insider with enough Form 4 purchase history. The metrics below reflect realized performance after each tracked open-market purchase.
| Metric | Value |
|---|---|
| InsiderAlpha rating | ★★★★★ (5/5) |
| Total purchases tracked | 40 |
| Purchases with forward-return data | 40 |
| 30-day win rate | 75% |
| 90-day win rate | 70% |
| Avg 5-day return | +5.26% |
| Avg 30-day return | +7.58% |
| Avg 90-day return | +37.33% |
| Best 30-day return |
InsiderAlpha's records for RA CAPITAL MANAGEMENT, L.P. go back to 2024: 84 primary Form 4 filings, an average of 28.0 per year. The typical open-market purchase is $15.06M (68 buys totaling $1.02B). The largest single buy on record is $394.57M of PBLS in 2026. Sales side: 110 recorded sales totaling $169.01M, so the filing history runs buy-heavy by dollar value. No transaction on record carries a Rule 10b5-1 flag - the filings look discretionary rather than pre-scheduled, which makes their timing more informative as a signal.
Insiders who reported open-market trades in the last 12 months at the companies RA CAPITAL MANAGEMENT, L.P. files at. Multiple unrelated insiders buying the same stock within a short window, cluster buying, has historically been one of the strongest Form 4 signals.
Other corporate insiders with significant SEC Form 4 track records on InsiderAlpha:
RA CAPITAL MANAGEMENT, L.P. is an investment firm, tracked as 10% Owner of Vor Biopharma Inc. (VOR). InsiderAlpha holds 84 primary Form 4 filings for it, the earliest from 2024, updated as new SEC EDGAR filings are processed.
34 primary Form 4 filings in the last 90 days, covering 19 companies.
Recorded transactions: 68 open-market purchases ($1.02B) and 110 open-market sales ($169.01M) across all tracked filings.
Across 40 tracked purchases, RA CAPITAL MANAGEMENT, L.P. averaged +7.6% avg 30-day return with a 75% 30-day win rate. InsiderAlpha rates the track record at 5/5 stars.
All Form 4 filings, transaction values, and 10b5-1 plan flags are listed on this page and updated in real time as new SEC EDGAR filings are processed.
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$SEPN Septerna, Inc.746.5K shares @ $42.50$31.73M
| +141.53% |