WAVE Life Sciences Inc is a clinical-stage biotechnology company focused on unlocking the broad potential of RNA medicines also known as oligonucleotides, targeting ribonucleic acid (RNA), to transform human health. RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation, and deep insights into human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. Its toolkit of RNA-targeting modalities includes RNA editing, antisense silencing, and RNA interference, providing capabilities for designing and sustainably delivering candidates that optimally address disease biology. Its programs are for rare and prevalent diseases, including alpha-1 antitrypsin deficiency, obesity, Duchenne muscular dystrophy, and Huntington's disease.
https://www.wavelifesciences.comSEC filings for WVE on EDGAR
| Form 4 transaction type | Transactions | Shares | Total value |
|---|---|---|---|
| Open-market sale | 4 | 23,996 | $135K |
| Option exercise | 2 | 14,000 |
Dollar totals are shown for open-market purchases and sales only. Grants, option exercises, gifts and tax withholding are reported by share count because they are not trades at a market price.
42 Form 4 filings on record, the earliest from Oct 1, 2024, newest first. Filing history page 1 of 2.
| Date | Insider | Transaction | Security | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Heidi L. Wagner - Director | Option exercise | Common Stock | 7,000 | $5.97 | $42K | |
| Heidi L. Wagner - Director | Open-market sale | Common Stock | 7,000 | $6.01 | $42K | |
| Heidi L. Wagner - Director | Option exercise | Stock Option (right to buy) | 7,000 | $0.00 | - | |
| Adrian Rawcliffe - Director | Open-market sale | Common Stock | 12,700 | $5.29 | $67K | |
| Ken Takanashi - Director | Open-market sale | Common Stock | 3,864 | $6.01 | $23K | |
| Aik Na Tan - Director | Open-market sale | Common Stock | 432 | $6.01 | $3K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market purchase | Ordinary Shares | 4,954,558 | $6.06 | $30.02M | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market purchase | Ordinary Shares | 351,224 | $6.38 | $2.24M | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market purchase | Ordinary Shares | 2,495,623 | $6.43 | $16.05M | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market purchase | Ordinary Shares | 971,091 | $6.50 | $6.31M | |
| Ken Takanashi | Other | Ordinary Shares | 3,901,348 | $0.00 | - | |
| Ken Takanashi | Other | Series A Preferred Shares | 3,901,348 | $0.00 | - | |
| Chris Francis - Officer | Option exercise | Ordinary Shares | 17,900 | $3.87 | $69K | |
| Chris Francis - Officer | Open-market sale | Ordinary Shares | 17,900 | $15.09 | $270K | |
| Chris Francis - Officer | Option exercise | Ordinary Shares | 15,294 | $4.75 | $73K | |
| Chris Francis - Officer | Open-market sale | Ordinary Shares | 15,294 | $15.00 | $229K | |
| Chris Francis - Officer | Option exercise | Share Option (right to buy) | 17,900 | $0.00 | - | |
| Chris Francis - Officer | Option exercise | Share Option (right to buy) | 15,294 | $0.00 | - | |
| Kyle Moran - Officer | Grant or award | Ordinary Shares | 45,625 | $0.00 | - | |
| Kyle Moran - Officer | Open-market sale | Ordinary Shares | 3,588 | $13.45 | $48K | |
| Kyle Moran - Officer | Grant or award | Share Option (right to buy) | 273,750 | $0.00 | - | |
| Paul Bolno - Officer | Grant or award | Ordinary Shares | 165,000 | $0.00 | - | |
| Paul Bolno - Officer | Open-market sale | Ordinary Shares | 10,480 | $13.45 | $141K | |
| Paul Bolno - Officer | Grant or award | Share Option (right to buy) | 1,000,000 | $0.00 | - | |
| Chris Francis - Officer | Grant or award | Ordinary Shares | 38,750 | $0.00 | - | |
| Chris Francis - Officer | Open-market sale | Ordinary Shares | 1,883 | $13.45 | $25K | |
| Chris Francis - Officer | Grant or award | Share Option (right to buy) | 232,500 | $0.00 | - | |
| Chandra Vargeese - Officer | Grant or award | Ordinary Shares | 45,625 | $0.00 | - | |
| Chandra Vargeese - Officer | Open-market sale | Ordinary Shares | 3,228 | $13.45 | $43K | |
| Chandra Vargeese - Officer | Grant or award | Share Option (right to buy) | 273,750 | $0.00 | - | |
| Chris Francis - Officer | Option exercise | Ordinary Shares | 9,375 | $3.14 | $29K | |
| Chris Francis - Officer | Open-market sale | Ordinary Shares | 8,080 | $15.92 | $129K | |
| Chris Francis - Officer | Open-market sale | Ordinary Shares | 1,295 | $16.70 | $22K | |
| Chris Francis - Officer | Option exercise | Share Option (right to buy) | 9,375 | $0.00 | - | |
| Adrian Rawcliffe | Option exercise | Ordinary Shares | 42,000 | $5.97 | $251K | |
| Adrian Rawcliffe | Open-market sale | Ordinary Shares | 42,000 | $15.00 | $630K | |
| Adrian Rawcliffe | Option exercise | Share Option (right to buy) | 42,000 | $0.00 | - | |
| Heidi L. Wagner | Option exercise | Ordinary Shares | 7,000 | $5.97 | $42K | |
| Heidi L. Wagner | Option exercise | Ordinary Shares | 7,000 | $5.97 | $42K | |
| Heidi L. Wagner | Open-market sale | Ordinary Shares | 7,000 | $13.00 | $91K | |
| Heidi L. Wagner | Option exercise | Share Option (right to buy) | 14,000 | $0.00 | - | |
| Heidi L. Wagner | Open-market sale | Ordinary Shares | 7,000 | $14.00 | $98K | |
| Christian O. Henry | Open-market sale | Ordinary Shares | 6,445 | $12.75 | $82K | |
| Christian O. Henry | Option exercise | Ordinary Shares | 42,000 | $5.97 | $251K | |
| Christian O. Henry | Open-market sale | Ordinary Shares | 42,000 | $12.75 | $536K | |
| Christian O. Henry | Option exercise | Ordinary Shares | 15,000 | $3.50 | $53K | |
| Christian O. Henry | Open-market sale | Ordinary Shares | 15,000 | $14.07 | $211K | |
| Christian O. Henry | Option exercise | Ordinary Shares | 30,000 | $4.59 | $138K | |
| Christian O. Henry | Open-market sale | Ordinary Shares | 30,000 | $18.02 | $541K | |
| Christian O. Henry | Option exercise | Share Option (right to buy) | 42,000 | $0.00 | - | |
| Christian O. Henry | Option exercise | Share Option (right to buy) | 15,000 | $0.00 | - | |
| Christian O. Henry | Option exercise | Share Option (right to buy) | 30,000 | $0.00 | - | |
| Aik Na Tan | Open-market sale | Ordinary Shares | 7,494 | $12.75 | $96K | |
| Aik Na Tan | Open-market sale | Ordinary Shares | 7,494 | $15.00 | $112K | |
| Aik Na Tan | Option exercise | Share Option (right to buy) | 21,000 | $0.00 | - | |
| Aik Na Tan | Option exercise | Ordinary Shares | 32,230 | $5.37 | $173K | |
| Aik Na Tan | Open-market sale | Ordinary Shares | 15,000 | $12.75 | $191K | |
| Aik Na Tan | Open-market sale | Ordinary Shares | 17,230 | $15.00 | $258K | |
| Aik Na Tan | Option exercise | Ordinary Shares | 45,000 | $4.59 | $206K | |
| Aik Na Tan | Open-market sale | Ordinary Shares | 20,000 | $12.75 | $255K | |
| Aik Na Tan | Open-market sale | Ordinary Shares | 25,000 | $15.00 | $375K | |
| Aik Na Tan | Option exercise | Ordinary Shares | 21,000 | $3.50 | $74K | |
| Aik Na Tan | Open-market sale | Ordinary Shares | 21,000 | $12.75 | $268K | |
| Aik Na Tan | Open-market sale | Ordinary Shares | 21,000 | $12.75 | $268K | |
| Aik Na Tan | Option exercise | Ordinary Shares | 21,000 | $5.97 | $125K | |
| Aik Na Tan | Option exercise | Share Option (right to buy) | 32,230 | $0.00 | - | |
| Aik Na Tan | Option exercise | Share Option (right to buy) | 45,000 | $0.00 | - | |
| Aik Na Tan | Option exercise | Share Option (right to buy) | 21,000 | $0.00 | - | |
| Gregory L. Verdine | Open-market sale | Ordinary Shares | 12,020 | $13.09 | $157K | |
| Gregory L. Verdine | Open-market sale | Ordinary Shares | 7,980 | $14.05 | $112K | |
| Chris Francis - Officer | Option exercise | Ordinary Shares | 28,125 | $3.14 | $88K | |
| Chris Francis - Officer | Open-market sale | Ordinary Shares | 28,125 | $14.50 | $408K | |
| Chris Francis - Officer | Option exercise | Ordinary Shares | 107,400 | $3.87 | $416K | |
| Chris Francis - Officer | Option exercise | Ordinary Shares | 22,500 | $2.83 | $64K | |
| Chris Francis - Officer | Open-market sale | Ordinary Shares | 107,400 | $14.56 | $1.56M | |
| Chris Francis - Officer | Option exercise | Ordinary Shares | 45,882 | $4.75 | $218K | |
| Chris Francis - Officer | Open-market sale | Ordinary Shares | 45,882 | $14.50 | $665K | |
| Chris Francis - Officer | Option exercise | Ordinary Shares | 9,375 | $3.14 | $29K | |
| Chris Francis - Officer | Open-market sale | Ordinary Shares | 9,375 | $15.00 | $141K | |
| Chris Francis - Officer | Option exercise | Ordinary Shares | 37,500 | $3.14 | $118K | |
| Chris Francis - Officer | Open-market sale | Ordinary Shares | 37,500 | $14.08 | $528K | |
| Chris Francis - Officer | Option exercise | Ordinary Shares | 17,900 | $3.87 | $69K | |
| Chris Francis - Officer | Open-market sale | Ordinary Shares | 17,900 | $15.00 | $269K | |
| Chris Francis - Officer | Option exercise | Ordinary Shares | 122,349 | $4.75 | $581K | |
| Chris Francis - Officer | Open-market sale | Ordinary Shares | 122,349 | $14.20 | $1.74M | |
| Chris Francis - Officer | Option exercise | Ordinary Shares | 50,000 | $10.48 | $524K | |
| Chris Francis - Officer | Open-market sale | Ordinary Shares | 50,000 | $16.00 | $800K | |
| Chris Francis - Officer | Open-market sale | Ordinary Shares | 22,500 | $14.08 | $317K | |
| Chris Francis - Officer | Option exercise | Share Option (right to buy) | 75,000 | $0.00 | - | |
| Chris Francis - Officer | Option exercise | Share Option (right to buy) | 125,300 | $0.00 | - | |
| Chris Francis - Officer | Option exercise | Share Option (right to buy) | 168,231 | $0.00 | - | |
| Chris Francis - Officer | Option exercise | Share Option (right to buy) | 50,000 | $0.00 | - | |
| Chris Francis - Officer | Option exercise | Share Option (right to buy) | 22,500 | $0.00 | - | |
| Kyle Moran - Officer | Option exercise | Ordinary Shares | 60,000 | $2.83 | $170K | |
| Kyle Moran - Officer | Open-market sale | Ordinary Shares | 60,000 | $13.20 | $792K | |
| Kyle Moran - Officer | Option exercise | Ordinary Shares | 100,000 | $3.14 | $314K | |
| Kyle Moran - Officer | Open-market sale | Ordinary Shares | 50,000 | $15.00 | $750K | |
| Kyle Moran - Officer | Open-market sale | Ordinary Shares | 50,000 | $13.20 | $660K | |
| Kyle Moran - Officer | Option exercise | Ordinary Shares | 50,000 | $4.75 | $238K | |
| Kyle Moran - Officer | Open-market sale | Ordinary Shares | 50,000 | $18.00 | $900K | |
| Kyle Moran - Officer | Option exercise | Ordinary Shares | 36,000 | $8.17 | $294K | |
| Kyle Moran - Officer | Open-market sale | Ordinary Shares | 36 | $20.25 | $729 | |
| Kyle Moran - Officer | Option exercise | Ordinary Shares | 50,000 | $10.48 | $524K | |
| Kyle Moran - Officer | Open-market sale | Ordinary Shares | 50,000 | $20.03 | $1.00M | |
| Kyle Moran - Officer | Grant or award | Share Option (right to buy) | 60,000 | $0.00 | - | |
| Kyle Moran - Officer | Grant or award | Share Option (right to buy) | 100,000 | $0.00 | - | |
| Kyle Moran - Officer | Grant or award | Share Option (right to buy) | 50,000 | $0.00 | - | |
| Kyle Moran - Officer | Grant or award | Share Option (right to buy) | 36,000 | $0.00 | - | |
| Kyle Moran - Officer | Grant or award | Share Option (right to buy) | 50,000 | $0.00 | - | |
| Open-market sale | Ordinary Shares | 9,600 | $13.09 | $126K | ||
| Open-market sale | Ordinary Shares | 6,515 | $14.07 | $92K | ||
| Adrian Rawcliffe | Open-market sale | Ordinary Shares | 16,115 | $6.79 | $109K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market purchase | Ordinary Shares | 1,000 | $6.69 | $7K | |
| Paul Bolno - Officer | Open-market sale | Ordinary Shares | 217,351 | $10.10 | $2.19M | |
| Gregory L. Verdine | Open-market sale | Ordinary Shares | 10,000 | $10.00 | $100K | |
| Aik Na Tan | Option exercise | Ordinary Shares | 21,000 | $9.13 | $192K | |
| Aik Na Tan | Open-market sale | Ordinary Shares | 21,000 | $9.25 | $194K | |
| Aik Na Tan | Option exercise | Share Option (right to buy) | 21,000 | $0.00 | - | |
| Grant or award | Ordinary Shares | 12,700 | $0.00 | - | ||
| Grant or award | Share Option (right to buy) | 76,200 | $0.00 | - | ||
| Heidi L. Wagner | Grant or award | Ordinary Shares | 12,700 | $0.00 | - | |
| Heidi L. Wagner | Grant or award | Share Option (right to buy) | 76,200 | $0.00 | - | |
| Ken Takanashi | Grant or award | Ordinary Shares | 12,700 | $0.00 | - | |
| Ken Takanashi | Grant or award | Share Option (right to buy) | 76,200 | $0.00 | - | |
| Gregory L. Verdine | Grant or award | Ordinary Shares | 12,700 | $0.00 | - | |
| Gregory L. Verdine | Grant or award | Share Option (right to buy) | 76,200 | $0.00 | - | |
| Adrian Rawcliffe | Grant or award | Ordinary Shares | 12,700 | $0.00 | - | |
| Adrian Rawcliffe | Grant or award | Share Option (right to buy) | 76,200 | $0.00 | - |
A Form 144 is notice of an INTENDED sale, not a completed one. It often precedes the Form 4 that reports the trade actually happening.
| Filed | Filer | Relationship | Shares | Market value | Notice |
|---|---|---|---|---|---|
| ADRIAN G RAWCLIFFE | Director | 12,700 | $64K | View on EDGAR | |
| HEIDI L WAGNER | Director | 7,000 | $42K | View on EDGAR |
Wave Life Sciences, Inc. (WVE) had 4 insider filings in the last 90 days, with the most recent on 2026-08-14. The full record for WVE runs to 42 Form 4 filings, the earliest from 2024-10-01. InsiderAlpha tracks every Form 4, Form 144, and 8-K filing in real time.
No insider purchases of WVE were filed in the last 90 days. 6 purchases are on record for this company.
4 insider sales of WVE were filed in the last 90 days, totaling $135K.
This page tracks WVE Form 4 insider transactions, Form 144 sale notices, and 8-K material event disclosures in one timeline. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
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Every Form 4 below links to the original document on SEC EDGAR, so the numbers on this page can be checked against the filing they came from.
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