BeOne Medicines Ltd. (ONC)
$366.73-$5.76 (-1.55%) Today
John Oyler - OfficerJohn Oyler - OfficerJohn Oyler - OfficerJohn Oyler - OfficerJohn Oyler - OfficerJohn Oyler - OfficerFormerly known as BeiGene and founded in 2010 in Beijing, BeOne is a commercial-stage biotech firm that produces oncology therapeutics. The company's main product is Brukinsa, which is a small-molecule drug that treats multiple forms of non-Hodgkin lymphoma and leukemia. The company conducts drug discovery, runs global clinical trials, and manufactures drugs independently. As of 2025, Brukinsa made up 74% of total revenue, while it has two other approved commercialized drugs in its portfolio, Beqalzi and Tevimbra. While Brukinsa has global leadership, the other two drugs generate revenue mostly from China. Based on Brukinsa, BeOne competes mainly with AbbVie and AstraZeneca. The company also has more than 50 drugs in clinical trials in its active pipeline, focused on other cancers.
| Form 4 transaction type | Transactions | Shares | Total value |
|---|---|---|---|
| Open-market sale | 91 | 594,663 | $195.39M |
| Grant or award | 22 | 2,056,236 | |
| Option exercise | 26 | 3,321,038 |
Dollar totals are shown for open-market purchases and sales only. Grants, option exercises, gifts and tax withholding are reported by share count because they are not trades at a market price.
88 Form 4 filings on record, the earliest from Oct 1, 2024, newest first. Filing history page 3 of 3.
| Date | Insider | Transaction | Security | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Xiaodong Wang - Director | Gift | Ordinary Shares | 148,096 | $0.00 | - | |
| Lai Wang - Officer | Open-market sale | American Depositary Shares | 5,000 | $350.06 | $1.75M | |
| Corazon (Corsee) D. Sanders - Director | Option exercise | American Depositary Shares | 2,665 | $155.68 | $415K | |
| Corazon (Corsee) D. Sanders - Director | Open-market sale | American Depositary Shares | 2,665 | $337.00 | $898K | |
| Corazon (Corsee) D. Sanders - Director | Option exercise | Share Option (Right to Buy) | 34,645 | $0.00 | - | |
| Titus B. Ball - Officer | Open-market sale | American Depositary Shares | 122 | $326.76 | $40K | |
| Xiaobin Wu - Officer | Option exercise | American Depositary Shares | 22,773 | $174.43 | $3.97M | |
| Xiaobin Wu - Officer | Option exercise | American Depositary Shares | 27,085 | $155.68 | $4.22M | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 8,900 | $300.33 | $2.67M | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 4,500 | $301.49 | $1.36M | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 5,800 | $302.45 | $1.75M | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 3,517 | $303.54 | $1.07M | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 7,359 | $304.37 | $2.24M | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 528 | $305.59 | $161K | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 9,637 | $306.74 | $2.96M | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 9,617 | $307.38 | $2.96M | |
| Xiaobin Wu - Officer | Option exercise | American Depositary Shares | 30,756 | $155.68 | $4.79M | |
| Xiaobin Wu - Officer | Option exercise | American Depositary Shares | 9,180 | $159.03 | $1.46M | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 400 | $300.86 | $120K | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 5,800 | $302.04 | $1.75M | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 6,965 | $303.31 | $2.11M | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 500 | $304.19 | $152K | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 8,522 | $305.48 | $2.60M | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 12,232 | $306.26 | $3.75M | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 4,917 | $307.43 | $1.51M | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 600 | $308.03 | $185K | |
| Xiaobin Wu - Officer | Option exercise | Share Option (Right to Buy) | 296,049 | $0.00 | - | |
| Xiaobin Wu - Officer | Option exercise | Share Option (Right to Buy) | 352,105 | $0.00 | - | |
| Xiaobin Wu - Officer | Option exercise | Share Option (Right to Buy) | 399,828 | $0.00 | - | |
| Xiaobin Wu - Officer | Option exercise | Share Option (Right to Buy) | 119,340 | $0.00 | - | |
| Chan Henry Lee - Officer | Open-market sale | American Depositary Shares | 1,112 | $300.00 | $334K | |
| Chan Henry Lee - Officer | Option exercise | American Depositary Shares | 4,381 | $194.47 | $852K | |
| Chan Henry Lee - Officer | Option exercise | American Depositary Shares | 3,849 | $159.03 | $612K | |
| Chan Henry Lee - Officer | Open-market sale | American Depositary Shares | 6,052 | $300.19 | $1.82M | |
| Chan Henry Lee - Officer | Open-market sale | American Depositary Shares | 3,849 | $301.00 | $1.16M | |
| Chan Henry Lee - Officer | Option exercise | Share Option (Right to Buy) | 56,953 | $0.00 | - | |
| Chan Henry Lee - Officer | Option exercise | Share Option (Right to Buy) | 50,037 | $0.00 | - | |
| Aaron Rosenberg - Officer | Open-market sale | American Depositary Shares | 1,190 | $290.47 | $346K | |
| Chan Henry Lee - Officer | Open-market sale | American Depositary Shares | 920 | $304.60 | $280K | |
| Lai Wang - Officer | Open-market sale | American Depositary Shares | 2,949 | $302.00 | $891K | |
| Lai Wang - Officer | Open-market sale | American Depositary Shares | 292 | $302.92 | $88K | |
| Lai Wang - Officer | Open-market sale | American Depositary Shares | 800 | $304.16 | $243K | |
| Lai Wang - Officer | Open-market sale | American Depositary Shares | 259 | $305.00 | $79K | |
| Lai Wang - Officer | Open-market sale | American Depositary Shares | 700 | $300.00 | $210K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 6,703 | $252.23 | $1.69M | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 9,292 | $253.18 | $2.35M | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 10,254 | $254.10 | $2.61M | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 1,553 | $254.83 | $396K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 3,074 | $261.57 | $804K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 100 | $262.90 | $26K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 3,680 | $266.05 | $979K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 1,460 | $256.49 | $374K | |
| John Oyler - Officer | Grant or award | Ordinary Shares | 185,055 | $0.00 | - | |
| John Oyler - Officer | Grant or award | Share Option (Right to Buy) | 348,374 | $0.00 | - | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 1,400 | $250.84 | $351K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 1,400 | $251.88 | $353K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 1,000 | $253.49 | $253K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 927 | $254.97 | $236K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 400 | $255.74 | $102K | |
| Anthony C. Hooper - Director | Grant or award | Ordinary Shares | 10,985 | $0.00 | - | |
| Anthony C. Hooper - Director | Grant or award | Share Option (Right to Buy) | 22,750 | $0.00 | - | |
| BAKER BROS. ADVISORS LP | Grant or award | Ordinary Shares | 21,970 | $0.00 | - | |
| BAKER BROS. ADVISORS LP | Grant or award | Ordinary Shares | 21,970 | $0.00 | - | |
| BAKER BROS. ADVISORS LP | Grant or award | Share Option (Right to Buy) | 45,500 | $0.00 | - | |
| BAKER BROS. ADVISORS LP | Grant or award | Share Option (Right to Buy) | 45,500 | $0.00 | - | |
| John Oyler - Officer | Option exercise | Ordinary Shares | 4,055,415 | $0.50 | $2.03M | |
| John Oyler - Officer | Tax withholding / forfeiture | Ordinary Shares | 1,990,603 | $17.85 | $35.53M | |
| John Oyler - Officer | Option exercise | Share Option (Right to Buy) | 4,055,415 | $0.00 | - | |
| John Oyler - Officer | Option exercise | Ordinary Shares | 1,300,000 | $0.50 | $650K | |
| John Oyler - Officer | Option exercise | Share Option (Right to Buy) | 1,300,000 | $0.00 | - | |
| Xiaodong Wang - Director | Option exercise | American Depositary Shares | 41,760 | $6.50 | $271K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 2,600 | $183.60 | $477K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 7,063 | $184.83 | $1.31M | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 9,956 | $185.73 | $1.85M | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 9,266 | $186.99 | $1.73M | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 6,350 | $187.60 | $1.19M | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 1,300 | $188.79 | $245K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 1,833 | $190.57 | $349K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 993 | $191.78 | $190K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 1,374 | $192.61 | $265K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 725 | $194.01 | $141K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 300 | $195.67 | $59K | |
| Xiaodong Wang - Director | Option exercise | Share Option (Right to Buy) | 542,880 | $0.00 | - | |
| BAKER BROS. ADVISORS LP | Open-market sale | American Depositary Shares | 3,074 | $208.01 | $639K | |
| BAKER BROS. ADVISORS LP | Open-market sale | American Depositary Shares | 33,943 | $208.01 | $7.06M | |
| BAKER BROS. ADVISORS LP | Open-market sale | American Depositary Shares | 83,036 | $186.50 | $15.49M | |
| BAKER BROS. ADVISORS LP | Open-market sale | American Depositary Shares | 916,964 | $186.50 | $171.01M | |
| Xiaobin Wu - Officer | Open-market sale | RMB Shares | 0 | $0.00 | - | |
| HHLR ADVISORS, LTD. - 10% Owner | Open-market sale | Ordinary Shares | 17,842,500 | $200.00 | $3.57B | |
| Xiaodong Wang - Director | Option exercise | American Depositary Shares | 38,461 | $6.50 | $250K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 4,425 | $187.16 | $828K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 300 | $187.61 | $56K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 5,875 | $187.98 | $1.10M | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 400 | $188.55 | $75K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 2,700 | $189.17 | $511K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 200 | $189.76 | $38K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 6,187 | $190.32 | $1.18M | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 700 | $191.05 | $134K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 12,293 | $191.22 | $2.35M | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 407 | $191.81 | $78K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 6,981 | $191.96 | $1.34M | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 1,014 | $187.15 | $190K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 1,186 | $188.08 | $223K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 600 | $189.03 | $113K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 1,475 | $190.31 | $281K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 2,725 | $191.24 | $521K | |
| Xiaodong Wang - Director | Open-market sale | American Depositary Shares | 883 | $191.89 | $169K | |
| Xiaodong Wang - Director | Option exercise | Share Option (Right to Buy) | 499,993 | $0.00 | - | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 1,565 | $229.25 | $359K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 1,747 | $230.05 | $402K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 229 | $231.05 | $53K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 38 | $233.00 | $9K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 428 | $234.27 | $100K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 1,272 | $235.41 | $299K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 896 | $236.37 | $212K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 2,535 | $229.25 | $581K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 2,827 | $230.05 | $650K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 371 | $231.04 | $86K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 62 | $233.00 | $14K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 694 | $234.27 | $163K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 2,059 | $235.41 | $485K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 1,452 | $236.37 | $343K | |
| Shalini Sharp - Director | Grant or award | Ordinary Shares | 8,151 | $0.00 | - | |
| Shalini Sharp - Director | Grant or award | Share Option (Right to Buy) | 17,238 | $0.00 | - | |
| Chan Henry Lee - Officer | Open-market sale | American Depositary Shares | 1,202 | $237.10 | $285K | |
| Lai Wang - Officer | Open-market sale | American Depositary Shares | 5,000 | $220.35 | $1.10M |
A Form 144 is notice of an INTENDED sale, not a completed one. It often precedes the Form 4 that reports the trade actually happening.
| Filed | Filer | Relationship | Shares | Market value | Notice |
|---|---|---|---|---|---|
| XIAOBIN WU | Officer | 15,000 | $5.58M | View on EDGAR | |
| CORAZON D. SANDERS | Former Director | 2,075 | $789K | View on EDGAR | |
| CHAN LEE | Officer | 2,002 | $719K | View on EDGAR |
BeOne Medicines Ltd. (ONC) had 38 insider filings in the last 90 days, with the most recent on 2026-08-27. The full record for ONC runs to 88 Form 4 filings, the earliest from 2024-10-01. InsiderAlpha tracks every Form 4, Form 144, and 8-K filing in real time.
No insider purchases of ONC were filed in the last 90 days.
91 insider sales of ONC were filed in the last 90 days, totaling $195.39M.
This page tracks ONC Form 4 insider transactions, Form 144 sale notices, and 8-K material event disclosures in one timeline. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
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Every Form 4 below links to the original document on SEC EDGAR, so the numbers on this page can be checked against the filing they came from.
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