Updated Jul 16, 2026
BAKER BROS. ADVISORS LP has filed 15 SEC Form 4 filings across 11 companies in the last 90 days — active on both sides. Lifetime open-market purchases: $371.54M. Lifetime open-market sales: $195.52M. Historical track record: 5/5 stars across 66 tracked purchases.

| Role | Insider |
|---|---|
| Notability | 30/100 |
InsiderAlpha computes a forward-return-based score for every insider with enough Form 4 purchase history. The metrics below reflect realised performance after each tracked open-market purchase.
| InsiderAlpha rating | ★★★★★ (5/5) |
|---|---|
| Total purchases tracked | 66 |
| Purchases with forward-return data | 66 |
| 30-day win rate | 8788% |
| 90-day win rate | 7538% |
| Avg 5-day return | +545.92% |
| Avg 30-day return | +1327.35% |
| Avg 90-day return | +2514.01% |
| Best 30-day return | +4586.78% |
| Date | Ticker | Company | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-07-02 | INCY | INCYTE CORP | A — Grant or award | 400 | $0.00 | |
| 2026-07-02 | INCY | INCYTE CORP | A — Grant or award | 400 | $0.00 | |
| 2026-06-18 | MDGL | MADRIGAL PHARMACEUTICALS, INC. | A — Grant or award | 908 | $0.00 | |
| 2026-06-18 | MDGL | MADRIGAL PHARMACEUTICALS, INC. | A — Grant or award | 908 | $0.00 | |
| 2026-06-15 | ONC | BeOne Medicines Ltd. | A — Grant or award | 19.0K | $0.00 | |
| 2026-06-15 | ONC | BeOne Medicines Ltd. | A — Grant or award | 19.0K | $0.00 | |
| 2026-06-10 | INCY | INCYTE CORP | A — Grant or award | 1.6K | $0.00 | |
| 2026-06-10 | INCY | INCYTE CORP | A — Grant or award | 1.6K | $0.00 | |
| 2026-06-05 | DNLI | Denali Therapeutics Inc. | A — Grant or award | 6.4K | $0.00 | |
| 2026-06-05 | DNLI | Denali Therapeutics Inc. | A — Grant or award | 6.4K | $0.00 | |
| 2026-06-02 | ACAD | ACADIA PHARMACEUTICALS INC | A — Grant or award | 18.6K | $0.00 | |
| 2026-06-02 | ACAD | ACADIA PHARMACEUTICALS INC | A — Grant or award | 18.6K | $0.00 | |
| 2026-06-02 | KNSA | Kiniksa Pharmaceuticals International, plc | A — Grant or award | 6.1K | $0.00 | |
| 2026-06-02 | KNSA | Kiniksa Pharmaceuticals International, plc | A — Grant or award | 6.1K | $0.00 | |
| 2026-05-27 | ONC | BeOne Medicines Ltd. | S — Open-market sale | 2.8K | $23.79 | $66K |
| 2026-05-27 | ONC | BeOne Medicines Ltd. | S — Open-market sale | 2.8K | $23.79 | $66K |
| 2026-05-27 | ONC | BeOne Medicines Ltd. | S — Open-market sale | 2.7K | $23.85 | $65K |
| 2026-05-27 | ONC | BeOne Medicines Ltd. | S — Open-market sale | 2.7K | $23.85 | $65K |
| 2026-05-11 | INCY | INCYTE CORP | M — Option exercise | 15.0K | $84.53 | $1.27M |
| 2026-05-11 | INCY | INCYTE CORP | M — Option exercise | 15.0K | $84.53 | $1.27M |
BAKER BROS. ADVISORS LP is a corporate insider — currently tracked as Insider of Kodiak Sciences Inc. (KOD). InsiderAlpha tracks every SEC Form 4 filing in real time.
15 primary Form 4 filings in the last 90 days, covering 11 companies.
Recorded transactions: 68 open-market purchases ($371.54M) and 12 open-market sales ($195.52M) across all tracked filings.
Across 66 tracked purchases, BAKER BROS. ADVISORS LP averaged +1327.4% avg 30-day return with a 8788% 30-day win rate. InsiderAlpha rates the track record at 5/5 stars.
All Form 4 filings, transaction values, and 10b5-1 plan flags are listed on this page and updated in real time as new SEC EDGAR filings are processed.
Open the live BAKER BROS. ADVISORS LP profile on InsiderAlpha for real-time alerts, AI-scored trade ideas, and full transaction history.