BeOne Medicines Ltd. (ONC)
Data as of , from SEC Form 4 filings.
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About BeOne Medicines Ltd. (ONC)
Formerly known as BeiGene and founded in 2010 in Beijing, BeOne is a commercial-stage biotech firm that produces oncology therapeutics. The company's main product is Brukinsa, which is a small-molecule drug that treats multiple forms of non-Hodgkin lymphoma and leukemia. The company conducts drug discovery, runs global clinical trials, and manufactures drugs independently. As of 2025, Brukinsa made up 74% of total revenue, while it has two other approved commercialized drugs in its portfolio, Beqalzi and Tevimbra. While Brukinsa has global leadership, the other two drugs generate revenue mostly from China. Based on Brukinsa, BeOne competes mainly with AbbVie and AstraZeneca. The company also has more than 50 drugs in clinical trials in its active pipeline, focused on other cancers.
- BASEL
- 12,000
- 2016
- XNAS
ONC Form 4 activity by transaction type, last 90 days
| Form 4 transaction type | Transactions | Shares | Total value |
|---|---|---|---|
| Open-market sale | 72 | 492,529 | $168.69M |
| Option exercise | 20 | 2,310,112 |
Dollar totals cover purchases and sales only (codes P and S). Grants, option exercises, gifts and tax withholding are counted in shares, because none of them is a trade at a market price.
ONC insider transactions (Form 4)
9192 Form 4 filings on record, the earliest from Oct 1, 2024, newest first. Filing history page 2 of 3.
| Date | Insider | Transaction | Security | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Elizabeth Fisher Mooney - Director | Grant or award | Ordinary Shares | 18,980 | $0.00 | - | |
| Margaret Dugan - Director | Grant or award | Ordinary Shares | 18,980 | $0.00 | - | |
 Charles Lazelle Sawyers - Director | Grant or award | Ordinary Shares | 18,980 | $0.00 | - | |
| Shalini Sharp - Director | Grant or award | Ordinary Shares | 18,980 | $0.00 | - | |
| Alessandro Riva - Director | Grant or award | Ordinary Shares | 18,980 | $0.00 | - | |
| BAKER BROS. ADVISORS LP | Grant or award | Ordinary Shares | 18,980 footnote F1 | $0.00 | - | |
| BAKER BROS. ADVISORS LP | Grant or award | Ordinary Shares | 18,980 footnote F1 | $0.00 | - | |
| ||||||
| Titus B. Ball - Officer | Open-market sale | American Depositary Shares | 100 | $271.06 footnote F3 | $27K | |
| Titus B. Ball - Officer | Open-market sale | American Depositary Shares | 36 | $272.08 footnote F4 | $10K | |
| ||||||
| Chan Henry Lee - Officer | Open-market sale | American Depositary Shares | 711 | $270.24 footnote F3 | $192K | |
| Chan Henry Lee - Officer | Open-market sale | American Depositary Shares | 160 | $271.26 footnote F4 | $43K | |
| ||||||
| Lai Wang - Officer | Open-market sale | American Depositary Shares | 1,327 | $269.34 footnote F7 | $357K | |
| Lai Wang - Officer | Open-market sale | American Depositary Shares | 40 | $270.73 | $11K | |
| ||||||
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 1,444 | $269.33 footnote F4 | $389K | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 40 | $270.55 | $11K | |
| ||||||
 John Oyler - Officer | Open-market sale | American Depositary Shares | 1,120 | $271.14 footnote F9 | $304K | |
| John Oyler - Officer | Open-market sale | American Depositary Shares | 3,820 | $270.38 footnote F8 | $1.03M | |
| ||||||
| Qingqing Yi - Director | Open-market sale | American Depositary Shares | 235 | $279.13 | $66K | |
| Alessandro Riva - Director | Open-market sale | American Depositary Shares | 212 | $309.51 | $66K | |
| Margaret Dugan - Director | Open-market sale | American Depositary Shares | 212 | $309.60 | $66K | |
| Corazon (Corsee) D. Sanders - Director | Open-market sale | American Depositary Shares | 212 | $309.59 | $66K | |
| BAKER BROS. ADVISORS LP | Open-market sale | Ordinary Shares | 2,743 footnote F1,F13 | $23.85 | $65K | |
| BAKER BROS. ADVISORS LP | Open-market sale | Ordinary Shares | 2,743 footnote F1,F13 | $23.85 | $65K | |
| BAKER BROS. ADVISORS LP | Open-market sale | Ordinary Shares | 2,756 footnote F1,F13 | $23.79 | $66K | |
| BAKER BROS. ADVISORS LP | Open-market sale | Ordinary Shares | 2,756 footnote F1,F13 | $23.79 | $66K | |
| ||||||
| Chan Henry Lee - Officer | Option exercise | American Depositary Shares | 101 | $194.47 | $20K | |
| Chan Henry Lee - Officer | Option exercise | American Depositary Shares | 133 | $213.32 | $28K | |
| Chan Henry Lee - Officer | Option exercise | American Depositary Shares | 98 | $159.03 | $16K | |
| Chan Henry Lee - Officer | Open-market sale | American Depositary Shares | 332 | $310.72 | $103K | |
| Chan Henry Lee - Officer | Option exercise | Share Option (Right to Buy) | 1,313 | $0.00 | - | |
| Chan Henry Lee - Officer | Option exercise | Share Option (Right to Buy) | 1,729 | $0.00 | - | |
| Chan Henry Lee - Officer | Option exercise | Share Option (Right to Buy) | 1,274 | $0.00 | - | |
| Chan Henry Lee - Officer | Option exercise | American Depositary Shares | 101 | $194.47 | $20K | |
| Chan Henry Lee - Officer | Option exercise | American Depositary Shares | 133 | $213.32 | $28K | |
| Chan Henry Lee - Officer | Option exercise | American Depositary Shares | 98 | $159.03 | $16K | |
| Chan Henry Lee - Officer | Open-market sale | American Depositary Shares | 332 | $311.59 | $103K | |
| Chan Henry Lee - Officer | Option exercise | Share Option (Right to Buy) | 1,313 | $0.00 | - | |
| Chan Henry Lee - Officer | Option exercise | Share Option (Right to Buy) | 1,729 | $0.00 | - | |
| Chan Henry Lee - Officer | Option exercise | Share Option (Right to Buy) | 1,274 | $0.00 | - | |
| Chan Henry Lee - Officer | Option exercise | American Depositary Shares | 110 | $194.47 | $21K | |
| Chan Henry Lee - Officer | Option exercise | American Depositary Shares | 133 | $213.32 | $28K | |
| Chan Henry Lee - Officer | Option exercise | American Depositary Shares | 98 | $159.03 | $16K | |
| Chan Henry Lee - Officer | Open-market sale | American Depositary Shares | 341 | $300.00 | $102K | |
| Chan Henry Lee - Officer | Option exercise | Share Option (Right to Buy) | 1,430 | $0.00 | - | |
| Chan Henry Lee - Officer | Option exercise | Share Option (Right to Buy) | 1,729 | $0.00 | - | |
| Chan Henry Lee - Officer | Option exercise | Share Option (Right to Buy) | 1,274 | $0.00 | - | |
| John Oyler - Officer | Grant or award | Ordinary Shares | 117,936 footnote F2 | $0.00 | - | |
| John Oyler - Officer | Grant or award | Ordinary Shares | 326,976 footnote F1 | $0.00 | - | |
| ||||||
| Chan Henry Lee - Officer | Grant or award | Ordinary Shares | 29,874 footnote F2 | $0.00 | - | |
| Chan Henry Lee - Officer | Grant or award | Ordinary Shares | 65,390 footnote F1 | $0.00 | - | |
| ||||||
| Lai Wang - Officer | Grant or award | Ordinary Shares | 112,606 footnote F1 | $0.00 | - | |
| Lai Wang - Officer | Grant or award | Ordinary Shares | 55,029 footnote F2 | $0.00 | - | |
| ||||||
| Xiaobin Wu - Officer | Grant or award | Ordinary Shares | 168,922 footnote F1 | $0.00 | - | |
| Xiaobin Wu - Officer | Grant or award | Ordinary Shares | 78,624 footnote F2 | $0.00 | - | |
| ||||||
| Aaron Rosenberg - Officer | Grant or award | Ordinary Shares | 79,014 footnote F1 | $0.00 | - | |
| Aaron Rosenberg - Officer | Grant or award | Ordinary Shares | 40,573 footnote F2 | $0.00 | - | |
| ||||||
| Chan Henry Lee - Officer | Option exercise | American Depositary Shares | 502 | $194.47 | $98K | |
| Chan Henry Lee - Officer | Option exercise | American Depositary Shares | 662 | $213.32 | $141K | |
| Chan Henry Lee - Officer | Option exercise | American Depositary Shares | 496 | $159.03 | $79K | |
| Chan Henry Lee - Officer | Open-market sale | American Depositary Shares | 664 | $348.79 | $232K | |
| Chan Henry Lee - Officer | Open-market sale | American Depositary Shares | 996 | $350.00 | $349K | |
| Chan Henry Lee - Officer | Option exercise | Share Option (Right to Buy) | 6,526 | $0.00 | - | |
| Chan Henry Lee - Officer | Option exercise | Share Option (Right to Buy) | 8,606 | $0.00 | - | |
| Chan Henry Lee - Officer | Option exercise | Share Option (Right to Buy) | 6,448 | $0.00 | - | |
| Corazon (Corsee) D. Sanders - Director | Option exercise | American Depositary Shares | 2,627 | $159.03 | $418K | |
| Corazon (Corsee) D. Sanders - Director | Open-market sale | American Depositary Shares | 1,823 | $340.20 footnote F2 | $620K | |
| Corazon (Corsee) D. Sanders - Director | Open-market sale | American Depositary Shares | 804 | $342.47 footnote F3 | $275K | |
| Corazon (Corsee) D. Sanders - Director | Option exercise | Share Option (Right to Buy) | 34,151 | $0.00 | - | |
| ||||||
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 3,155 | $380.23 footnote F2 | $1.20M | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 826 | $381.19 footnote F3 | $315K | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 10 | $382.32 | $4K | |
| ||||||
| Chan Henry Lee - Officer | Option exercise | American Depositary Shares | 302 | $194.47 | $59K | |
| Chan Henry Lee - Officer | Option exercise | American Depositary Shares | 398 | $213.32 | $85K | |
| Chan Henry Lee - Officer | Option exercise | American Depositary Shares | 296 | $159.03 | $47K | |
| Chan Henry Lee - Officer | Open-market sale | American Depositary Shares | 664 | $348.75 | $232K | |
| Chan Henry Lee - Officer | Open-market sale | American Depositary Shares | 332 | $350.00 | $116K | |
| Chan Henry Lee - Officer | Option exercise | Share Option (Right to Buy) | 3,926 | $0.00 | - | |
| Chan Henry Lee - Officer | Option exercise | Share Option (Right to Buy) | 5,174 | $0.00 | - | |
| Chan Henry Lee - Officer | Option exercise | Share Option (Right to Buy) | 3,848 | $0.00 | - | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 500 | $350.44 footnote F3 | $175K | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 3,240 | $351.41 footnote F4 | $1.14M | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 789 | $352.78 footnote F5 | $278K | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 251 | $354.20 footnote F6 | $89K | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 120 | $355.00 | $43K | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 100 | $357.43 footnote F7 | $36K | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 4,846 | $360.10 footnote F8 | $1.75M | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 154 | $362.07 footnote F9 | $56K | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 4,240 | $380.33 footnote F10 | $1.61M | |
| Xiaobin Wu - Officer | Open-market sale | American Depositary Shares | 1,769 | $381.05 footnote F11 | $674K | |
| ||||||
| John Oyler - Officer | Gift | Ordinary Shares | 151,320 | $0.00 footnote F1 | - | |
| John Oyler - Officer | Gift | Ordinary Shares | 858,533 | $0.00 footnote F1 | - | |
| ||||||
Item 2.02, 9.01
Item 2.02, 9.01
Item 8.01
Item 5.02, 5.07, 9.01
Recent ONC Form 144 notices of proposed sale
3An insider files Form 144 before selling restricted or control stock. It announces a planned sale. If the sale goes ahead, it shows up later on a Form 4.
| Filed | Filer | Relationship | Shares | Market value | Notice |
|---|---|---|---|---|---|
| CHAN LEE | Officer | 1,115 | $407K | View on EDGAR | |
| XIAODONG WANG | Director, Chair, Scientific Advisory Brd | 131,370 |
ONC insider trading FAQ
What is the latest insider trade for ONC?
BeOne Medicines Ltd. (ONC) had 12 insider filings in the last 90 days, with the most recent on 2026-10-02. The full record for ONC runs to 92 Form 4 filings, the earliest from 2024-10-01. InsiderAlpha adds new Form 4, Form 144 and 8-K filings as they arrive from SEC EDGAR.
How many insiders are buying ONC stock?
No insider purchases of ONC were filed in the last 90 days.
How many insiders are selling ONC stock?
72 insider sales of ONC were filed in the last 90 days, totaling $168.69M.
Where can I see ONC SEC filings (Form 4, 10-K, 10-Q, 8-K)?
This page collects ONC Form 4 insider transactions, Form 144 sale notices and 8-K filings in one place. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
More Health Care companies with insider activity
Recent insider filings
10The EDGAR links open each original Form 4, so you can check any number on this page against the filing it came from.
- - Chan Henry Lee view on EDGAR
- - Xiaodong Wang view on EDGAR
- - Xiaodong Wang view on EDGAR
- - Titus B. Ball view on EDGAR
- - Xiaobin Wu view on EDGAR
- - Chan Henry Lee view on EDGAR
- - John Oyler view on EDGAR
- - Aaron Rosenberg view on EDGAR
- - Chan Henry Lee view on EDGAR
Related companies with recent insider activity
Learn more
- Insider selling: signal or noise?
- Why most insider sales are routine, and the few patterns worth a second look.
- Form 144 vs Form 4
- A Form 144 announces a planned sale; the Form 4 reports it after it happens.
- Insider activity in Health Care
- Where ONC's peers are being bought and sold.
- Every recent Form 4
- The market-wide feed, updated as filings arrive from SEC EDGAR.
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