Septerna, Inc. (SEPN)
Data as of , from SEC Form 4 filings.
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About Septerna, Inc. (SEPN)
Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
- SOUTH SAN FRANCISCO, CA
- 130
- 2024
- XNAS
SEPN Form 4 activity by transaction type, last 90 days
| Form 4 transaction type | Transactions | Shares | Total value |
|---|---|---|---|
| Open-market sale | 8 | 1,671,867 | $72.19M |
| Grant or award | 1 | 275,000 | |
| Option exercise | 10 | 63,334 |
Dollar totals cover purchases and sales only (codes P and S). Grants, option exercises, gifts and tax withholding are counted in shares, because none of them is a trade at a market price.
SEPN insider transactions (Form 4)
2944 Form 4 filings on record, the earliest from Oct 28, 2024, newest first. Filing history page 2 of 2.
| Date | Insider | Transaction | Security | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jeffrey Finer - Officer | Grant or award | Stock Option (Right to Buy) | 400,000 | $0.00 | - | |
| Mark Andrew Wilson - Officer | Grant or award | Stock Option (Right to Buy) | 165,000 | $0.00 | - | |
| Daniel D. Long - Officer | Open-market sale | Common Stock | 3,501 | $18.06 footnote F1 | $63K | |
| ||||||
| Keith Michael Gottesdiener | Grant or award | Stock Option (Right to Buy) | 33,246 | $0.00 | - | |
| Uwe Klein - Officer | Option exercise | Common Stock | 10,452 | $2.76 | $29K | |
| Uwe Klein - Officer | Option exercise | Common Stock | 4,935 | $2.76 | $14K | |
| Uwe Klein - Officer | Option exercise | Common Stock | 7,621 | $6.81 | $52K | |
| Uwe Klein - Officer | Option exercise | Stock Option (Right to Buy) | 10,452 | $0.00 | - | |
| Uwe Klein - Officer | Option exercise | Stock Option (Right to Buy) | 4,935 | $0.00 | - | |
| Uwe Klein - Officer | Option exercise | Stock Option (Right to Buy) | 7,621 | $0.00 | - | |
| Samira Shaikhly - Officer | Grant or award | Stock Option (Right to Buy) | 30,000 | $0.00 | - | |
| Jeffrey Finer - Officer | Grant or award | Stock Option (Right to Buy) | 210,000 | $0.00 | - | |
| Daniel D. Long - Officer | Grant or award | Stock Option (Right to Buy) | 30,000 | $0.00 | - | |
| Uwe Klein - Officer | Grant or award | Stock Option (Right to Buy) | 30,000 | $0.00 | - | |
| Jae B. Kim - Officer | Grant or award | Stock Option (Right to Buy) | 55,000 | $0.00 | - | |
| Elizabeth Bhatt - Officer | Grant or award | Stock Option (Right to Buy) | 95,000 | $0.00 | - | |
| Gil M. Labrucherie - Officer | Grant or award | Stock Option (Right to Buy) | 37,500 | $0.00 | - | |
| RA CAPITAL MANAGEMENT, L.P. | Other | Common Stock | 1,695,515 | - | - | |
| RA CAPITAL MANAGEMENT, L.P. | Other | Common Stock | 1,130,343 | - | - | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market purchase | Common Stock | 3,828,400 | $18.00 | $68.91M | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market purchase | Common Stock | 341,600 | $18.00 | $6.15M | |
| RA CAPITAL MANAGEMENT, L.P. | Other | Series B Preferred Stock | 14,598,896 | - | - | |
| RA CAPITAL MANAGEMENT, L.P. | Other | Series B Preferred Stock | 9,732,596 | - | - | |
| Third Rock Ventures V, L.P. | Other | Common Stock | 4,790,773 | $0.00 | - | |
| Third Rock Ventures V, L.P. | Other | Common Stock | 2,872,956 | $0.00 | - | |
| Third Rock Ventures V, L.P. | Open-market purchase | Common Stock | 370,500 | $18.00 | $6.67M | |
| Third Rock Ventures V, L.P. | Open-market purchase | Common Stock | 279,500 | $18.00 | $5.03M | |
| Third Rock Ventures V, L.P. | Other | Series A Preferred Stock | 41,250,000 | $0.00 | - | |
| Third Rock Ventures V, L.P. | Other | Series B Preferred Stock | 24,737,017 | $0.00 | - | |
Recent SEPN Form 144 notices of proposed sale
3An insider files Form 144 before selling restricted or control stock. It announces a planned sale. If the sale goes ahead, it shows up later on a Form 4.
| Filed | Filer | Relationship | Shares | Market value | Notice |
|---|---|---|---|---|---|
| DANIEL LONG | Officer | 10,001 | $391K | View on EDGAR | |
| SAMIRA SHAIKHLY | Officer | 12,592 |
SEPN insider trading FAQ
What is the latest insider trade for SEPN?
Septerna, Inc. (SEPN) had 6 insider filings in the last 90 days, with the most recent on 2026-09-10. The full record for SEPN runs to 44 Form 4 filings, the earliest from 2024-10-28. InsiderAlpha adds new Form 4, Form 144 and 8-K filings as they arrive from SEC EDGAR.
How many insiders are buying SEPN stock?
No insider purchases of SEPN were filed in the last 90 days. 4 purchases are on record for this company.
How many insiders are selling SEPN stock?
8 insider sales of SEPN were filed in the last 90 days, totaling $72.19M.
Where can I see SEPN SEC filings (Form 4, 10-K, 10-Q, 8-K)?
This page collects SEPN Form 4 insider transactions, Form 144 sale notices and 8-K filings in one place. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
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Recent insider filings
10The EDGAR links open each original Form 4, so you can check any number on this page against the filing it came from.
- - Rajiv Patni view on EDGAR
- - Daniel D. Long view on EDGAR
- - Third Rock Ventures V, L.P. view on EDGAR
- - RA CAPITAL MANAGEMENT, L.P. view on EDGAR
- - Elizabeth Bhatt view on EDGAR
- - Daniel D. Long view on EDGAR
- - Elizabeth Bhatt view on EDGAR
- - Daniel D. Long view on EDGAR
- - RA CAPITAL MANAGEMENT, L.P. view on EDGAR
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Learn more
- Insider selling: signal or noise?
- Why most insider sales are routine, and the few patterns worth a second look.
- Form 144 vs Form 4
- A Form 144 announces a planned sale; the Form 4 reports it after it happens.
- Insider activity in Health Care
- Where SEPN's peers are being bought and sold.
- Every recent Form 4
- The market-wide feed, updated as filings arrive from SEC EDGAR.
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