Stoke Therapeutics Inc is a biotechnology company dedicated to restoring protein expression by harnessing the bodys potential with RNA medicine. Its proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to restore naturally-occurring protein levels selectively. Its first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome. The company provides early programs focused on multiple targets, including haploinsufficiency diseases of the central nervous system and eye, to up-regulate the protein expression of the underlying disease gene in a mutation-agnostic manner.
https://www.stoketherapeutics.comSEC filings for STOK on EDGAR
| Form 4 transaction type | Transactions | Shares | Total value |
|---|---|---|---|
| Open-market sale | 12 | 37,851 | $1.19M |
| Grant or award | 8 | 349,502 | |
| Option exercise | 6 | 84,500 | |
| Bona-fide gift | 16 | 303,190 |
Dollar totals are shown for open-market purchases and sales only. Grants, option exercises, gifts and tax withholding are reported by share count because they are not trades at a market price.
84 Form 4 filings on record, the earliest from Oct 2, 2024, newest first. Filing history page 1 of 3.
| Date | Insider | Transaction | Security | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Barry Ticho - Officer | Option exercise | Common Stock | 10,000 | $0.00 | - | |
| Barry Ticho - Officer | Open-market sale | Common Stock | 4,525 | $32.01 | $145K | |
| Barry Ticho - Officer | Open-market sale | Common Stock | 242 | $32.47 | $8K | |
| Barry Ticho - Officer | Option exercise | Performance Stock Units | 10,000 | $0.00 | - | |
| Option exercise | Common Stock | 26,250 | $0.00 | - | ||
| Open-market sale | Common Stock | 11,930 | $32.01 | $382K | ||
| Open-market sale | Common Stock | 637 | $32.47 | $21K | ||
| Option exercise | Performance Stock Units | 26,250 | $0.00 | - | ||
| Option exercise | Common Stock | 6,000 | $0.00 | - | ||
| Open-market sale | Common Stock | 2,716 | $32.01 | $87K | ||
| Open-market sale | Common Stock | 145 | $32.47 | $5K | ||
| Option exercise | Performance Stock Units | 6,000 | $0.00 | - | ||
| Barry Ticho - Officer | Open-market sale | Common Stock | 5,907 | $28.95 | $171K | |
| Barry Ticho - Officer | Open-market sale | Common Stock | 1,269 | $29.45 | $37K | |
| Seth Loring Harrison | Gift | Stock Option (Right to Buy) | 29,555 | $0.00 | - | |
| Seth Loring Harrison | Gift | Stock Option (Right to Buy) | 14,777 | $0.00 | - | |
| Seth Loring Harrison | Gift | Stock Option (Right to Buy) | 14,777 | $0.00 | - | |
| Seth Loring Harrison | Gift | Stock Option (Right to Buy) | 29,555 | $0.00 | - | |
| Seth Loring Harrison | Gift | Stock Option (Right to Buy) | 11,650 | $0.00 | - | |
| Seth Loring Harrison | Gift | Stock Option (Right to Buy) | 11,650 | $0.00 | - | |
| Seth Loring Harrison | Gift | Stock Option (Right to Buy) | 21,000 | $0.00 | - | |
| Seth Loring Harrison | Gift | Stock Option (Right to Buy) | 21,000 | $0.00 | - | |
| Seth Loring Harrison | Gift | Stock Option (Right to Buy) | 19,441 | $0.00 | - | |
| Seth Loring Harrison | Gift | Stock Option (Right to Buy) | 19,441 | $0.00 | - | |
| Seth Loring Harrison | Gift | Stock Option (Right to Buy) | 7,639 | $0.00 | - | |
| Seth Loring Harrison | Gift | Stock Option (Right to Buy) | 7,639 | $0.00 | - | |
| Seth Loring Harrison | Gift | Stock Option (Right to Buy) | 29,747 | $0.00 | - | |
| Seth Loring Harrison | Gift | Stock Option (Right to Buy) | 29,747 | $0.00 | - | |
| Seth Loring Harrison | Gift | Stock Option (Right to Buy) | 17,786 | $0.00 | - | |
| Seth Loring Harrison | Gift | Stock Option (Right to Buy) | 17,786 | $0.00 | - | |
| Grant or award | Stock Option (Right to Buy) | 225,000 | $0.00 | - | ||
| Barry Ticho - Officer | Open-market sale | Common Stock | 6,728 | $32.62 | $219K | |
| Barry Ticho - Officer | Open-market sale | Common Stock | 500 | $33.27 | $17K | |
| Open-market sale | Common Stock | 1,457 | $29.95 | $44K | ||
| Arthur Tzianabos | Grant or award | Director Stock Option (Right to Buy) | 17,786 | $0.00 | - | |
| Julie Smith | Grant or award | Director Stock Option (Right to Buy) | 17,786 | $0.00 | - | |
| Grant or award | Director Stock Option (Right to Buy) | 17,786 | $0.00 | - | ||
| Adrian R. Krainer | Grant or award | Director Stock Option (Right to Buy) | 17,786 | $0.00 | - | |
| Grant or award | Director Stock Option (Right to Buy) | 17,786 | $0.00 | - | ||
| Seth Loring Harrison | Grant or award | Director Stock Option (Right to Buy) | 17,786 | $0.00 | - | |
| Jennifer Burstein | Grant or award | Director Stock Option (Right to Buy) | 17,786 | $0.00 | - | |
| Barry Ticho - Officer | Open-market sale | Common Stock | 1,795 | $30.58 | $55K | |
| Barry Ticho - Officer | Open-market sale | Common Stock | 2,243 | $32.79 | $74K | |
| Clare Kahn | Grant or award | Stock Option (Right to Buy) | 30,782 | $0.00 | - | |
| Barry Ticho - Officer | Open-market sale | Common Stock | 1,838 | $32.66 | $60K | |
| Open-market sale | Common Stock | 8,692 | $33.64 | $292K | ||
| Open-market sale | Common Stock | 601 | $34.41 | $21K | ||
| Barry Ticho - Officer | Open-market sale | Common Stock | 3,577 | $32.74 | $117K | |
| Barry Ticho - Officer | Open-market sale | Common Stock | 2,587 | $33.38 | $86K | |
| Barry Ticho - Officer | Open-market sale | Common Stock | 6,100 | $31.28 | $191K | |
| Barry Ticho - Officer | Open-market sale | Common Stock | 483 | $31.79 | $15K | |
| Barry Ticho - Officer | Open-market sale | Common Stock | 103 | $32.85 | $3K | |
| Barry Ticho - Officer | Option exercise | Common Stock | 1,365 | $2.19 | $3K | |
| Barry Ticho - Officer | Open-market sale | Common Stock | 1,461 | $29.99 | $44K | |
| Barry Ticho - Officer | Option exercise | Stock Option (Right to Buy) | 1,365 | $0.00 | - | |
| Open-market sale | Common Stock | 2,173 | $31.28 | $68K | ||
| Open-market sale | Common Stock | 172 | $31.79 | $5K | ||
| Open-market sale | Common Stock | 37 | $32.85 | $1K | ||
| Open-market sale | Common Stock | 1,274 | $32.74 | $42K | ||
| Open-market sale | Common Stock | 922 | $33.38 | $31K | ||
| Open-market sale | Common Stock | 1,033 | $32.74 | $34K | ||
| Open-market sale | Common Stock | 748 | $33.38 | $25K | ||
| Open-market sale | Common Stock | 1,762 | $31.28 | $55K | ||
| Open-market sale | Common Stock | 139 | $31.79 | $4K | ||
| Open-market sale | Common Stock | 30 | $32.85 | $986 | ||
| Open-market sale | Common Stock | 4,222 | $31.28 | $132K | ||
| Open-market sale | Common Stock | 334 | $31.79 | $11K | ||
| Open-market sale | Common Stock | 72 | $32.85 | $2K | ||
| Open-market sale | Common Stock | 2,476 | $32.74 | $81K | ||
| Open-market sale | Common Stock | 1,791 | $33.38 | $60K | ||
| Option exercise | Common Stock | 10,000 | $0.00 | - | ||
| Option exercise | Restricted Stock Units | 10,000 | $0.00 | - | ||
| Option exercise | Common Stock | 14,750 | $0.00 | - | ||
| Option exercise | Restricted Stock Units | 14,750 | $0.00 | - | ||
| Barry Ticho - Officer | Option exercise | Common Stock | 13,100 | $0.00 | - | |
| Barry Ticho - Officer | Option exercise | Common Stock | 10,000 | $0.00 | - | |
| Barry Ticho - Officer | Option exercise | Common Stock | 10,750 | $0.00 | - | |
| Barry Ticho - Officer | Option exercise | Restricted Stock Units | 13,100 | $0.00 | - | |
| Barry Ticho - Officer | Option exercise | Restricted Stock Units | 10,000 | $0.00 | - | |
| Barry Ticho - Officer | Option exercise | Restricted Stock Units | 10,750 | $0.00 | - | |
| Option exercise | Common Stock | 35,500 | $0.00 | - | ||
| Option exercise | Common Stock | 26,250 | $0.00 | - | ||
| Option exercise | Restricted Stock Units | 35,500 | $0.00 | - | ||
| Option exercise | Restricted Stock Units | 26,250 | $0.00 | - | ||
| Option exercise | Common Stock | 6,000 | $0.00 | - | ||
| Option exercise | Common Stock | 12,000 | $0.00 | - | ||
| Option exercise | Common Stock | 7,475 | $0.00 | - | ||
| Option exercise | Restricted Stock Units | 7,475 | $0.00 | - | ||
| Option exercise | Restricted Stock Units | 6,000 | $0.00 | - | ||
| Option exercise | Restricted Stock Units | 12,000 | $0.00 | - | ||
| Open-market sale | Common Stock | 605 | $36.80 | $22K |
A Form 144 is notice of an INTENDED sale, not a completed one. It often precedes the Form 4 that reports the trade actually happening.
| Filed | Filer | Relationship | Shares | Market value | Notice |
|---|---|---|---|---|---|
| BARUCH TICHO | Officer | 20,967 | $605K | View on EDGAR | |
| - | - | - | - | View on EDGAR | |
| - | - | - | - | View on EDGAR |
Stoke Therapeutics, Inc. (STOK) had 16 insider filings in the last 90 days, with the most recent on 2026-08-19. The full record for STOK runs to 84 Form 4 filings, the earliest from 2024-10-02. InsiderAlpha tracks every Form 4, Form 144, and 8-K filing in real time.
No insider purchases of STOK were filed in the last 90 days.
12 insider sales of STOK were filed in the last 90 days, totaling $1.19M.
This page tracks STOK Form 4 insider transactions, Form 144 sale notices, and 8-K material event disclosures in one timeline. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
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Every Form 4 below links to the original document on SEC EDGAR, so the numbers on this page can be checked against the filing they came from.
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