Sionna Therapeutics, Inc. (SION)
Data as of , from SEC Form 4 filings.
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About Sionna Therapeutics, Inc. (SION)
Sionna Therapeutics, Inc. files with the SEC under CIK 0002036042 and is classified as pharmaceutical preparations. We track it alongside the rest of the Health Care sector.
SION Form 4 activity by transaction type, last 90 days
| Form 4 transaction type | Transactions | Shares | Total value |
|---|---|---|---|
| Open-market sale | 2 | 3,448,811 | $21.84M |
| Grant or award | 12 | 1,329,232 | |
| Derivative transaction | 4 | 860,380 |
Dollar totals cover purchases and sales only (codes P and S). Grants, option exercises, gifts and tax withholding are counted in shares, because none of them is a trade at a market price.
SION insider transactions (Form 4)
15756 Form 4 filings on record, the earliest from Jul 1, 2025, newest first. Filing history page 2 of 2.
| Date | Insider | Transaction | Security | Shares | Price | Value |
|---|---|---|---|---|---|---|
| TPG GP A, LLC - 10% Owner | Open-market sale | Common Stock | 250,000 | $40.00 | $10.00M | |
| ORBIMED ADVISORS LLC - Director | Open-market sale | Common Stock | 33,356 | $44.55 | $1.49M | |
 Peter A. Thompson - Director | Open-market sale | Common Stock | 33,356 | $44.55 | $1.49M | |
| ORBIMED ADVISORS LLC - Director | Open-market sale | Common Stock | 900 | $44.50 | $40K | |
| ORBIMED ADVISORS LLC - Director | Open-market sale | Common Stock | 100 | $44.49 | $4K | |
| ORBIMED ADVISORS LLC - Director | Open-market sale | Common Stock | 875 | $44.49 | $39K | |
| Peter A. Thompson - Director | Open-market sale | Common Stock | 900 | $44.50 | $40K | |
| Peter A. Thompson - Director | Open-market sale | Common Stock | 100 | $44.49 | $4K | |
| Peter A. Thompson - Director | Open-market sale | Common Stock | 875 | $44.49 | $39K | |
| Peter A. Thompson - Director | Open-market sale | Common Stock | 94,583 | $44.54 | $4.21M | |
| Peter A. Thompson - Director | Open-market sale | Common Stock | 11,890 | $44.60 | $530K | |
| Peter A. Thompson - Director | Open-market sale | Common Stock | 1,600 | $44.49 | $71K | |
| ORBIMED ADVISORS LLC - Director | Open-market sale | Common Stock | 94,583 | $44.54 | $4.21M | |
| ORBIMED ADVISORS LLC - Director | Open-market sale | Common Stock | 11,890 | $44.60 | $530K | |
| ORBIMED ADVISORS LLC - Director | Open-market sale | Common Stock | 1,600 | $44.49 | $71K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 150 | $39.89 footnote F1 | $6K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 1,235 | $39.89 footnote F1 | $49K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 801 | $39.89 footnote F1 | $32K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 947 | $39.89 footnote F1 | $38K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 96 | $40.50 footnote F7 | $4K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 788 | $40.50 footnote F7 | $32K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 512 | $40.50 footnote F7 | $21K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 604 | $40.50 footnote F7 | $24K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 1,210 | $39.50 footnote F8 | $48K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 9,924 | $39.50 footnote F8 | $392K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 6,440 | $39.50 footnote F8 | $254K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 7,609 | $39.50 footnote F8 | $301K | |
| ||||||
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 17,913 | $40.20 footnote F1 | $720K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 11,626 | $40.20 footnote F1 | $467K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 13,734 | $40.20 footnote F1 | $552K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 1,701 | $41.05 footnote F7 | $70K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 13,964 | $41.05 footnote F7 | $573K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 9,063 | $41.05 footnote F7 | $372K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 10,707 | $41.05 footnote F7 | $440K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 53 | $42.10 footnote F8 | $2K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 433 | $42.10 footnote F8 | $18K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 280 | $42.10 footnote F8 | $12K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 331 | $42.10 footnote F8 | $14K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 332 | $39.57 footnote F9 | $13K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 2,728 | $39.57 footnote F9 | $108K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 1,770 | $39.57 footnote F9 | $70K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 2,092 | $39.57 footnote F9 | $83K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 2,276 | $40.01 footnote F10 | $91K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 18,684 | $40.01 footnote F10 | $748K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 12,126 | $40.01 footnote F10 | $485K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 14,325 | $40.01 footnote F10 | $573K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 2 | $40.61 | $81 | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 12 | $40.61 | $487 | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 8 | $40.61 | $325 | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 9 | $40.61 | $365 | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 2,182 | $40.20 footnote F1 | $88K | |
| ||||||
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 122,271 | $39.50 | $4.83M | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 66,672 | $39.50 | $2.63M | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 107,941 | $39.50 | $4.26M | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 3,624 | $39.58 footnote F6 | $143K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 31,392 | $39.58 footnote F6 | $1.24M | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 17,118 | $39.58 footnote F6 | $678K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 10,476 | $39.58 footnote F6 | $415K | |
| RA CAPITAL MANAGEMENT, L.P. | Open-market sale | Common Stock | 14,116 | $39.50 | $558K | |
| ||||||
| Michael Cloonan - Officer | Open-market sale | Common Stock | 22,895 | $36.60 footnote F4 | $838K | |
| Michael Cloonan - Officer | Option exercise | Common Stock | 33,532 | $6.11 | $205K | |
| Michael Cloonan - Officer | Open-market sale | Common Stock | 33,532 | $37.31 footnote F5 | $1.25M | |
| Michael Cloonan - Officer | Option exercise | Non-Qualified Stock Option (right to buy) | 13,324 | $0.00 | - | |
| Michael Cloonan - Officer | Option exercise | Non-Qualified Stock Option (right to buy) | 30,049 | $0.00 | - | |
| Michael Cloonan - Officer | Option exercise | Non-Qualified Stock Option (right to buy) | 22,895 | $0.00 | - | |
| Michael Cloonan - Officer | Option exercise | Non-Qualified Stock Option (right to buy) | 33,532 | $0.00 | - | |
| Michael Cloonan - Officer | Option exercise | Common Stock | 13,324 | $6.11 | $81K | |
| Michael Cloonan - Officer | Open-market sale | Common Stock | 13,324 | $34.44 footnote F2 | $459K | |
| Michael Cloonan - Officer | Option exercise | Common Stock | 30,049 | $6.11 | $184K | |
| Michael Cloonan - Officer | Open-market sale | Common Stock | 30,049 | $35.63 footnote F3 | $1.07M | |
| Michael Cloonan - Officer | Option exercise | Common Stock | 22,895 | $6.11 | $140K | |
| ||||||
 Bruce Booth | Open-market sale | Common Stock | 4,688 | $32.69 footnote F2 | $153K | |
| Bruce Booth | Open-market sale | Common Stock | 19,948 | $33.87 footnote F6 | $676K | |
| Bruce Booth | Open-market sale | Common Stock | 4,187 | $33.87 footnote F6 | $142K | |
| Bruce Booth | Open-market sale | Common Stock | 5,763 | $34.91 footnote F7 | $201K | |
| Bruce Booth | Open-market sale | Common Stock | 1,210 | $34.91 footnote F7 | $42K | |
| Bruce Booth | Open-market sale | Common Stock | 25,327 | $35.69 footnote F8 | $904K | |
| Bruce Booth | Open-market sale | Common Stock | 5,316 | $35.69 footnote F8 | $190K | |
| Bruce Booth | Open-market sale | Common Stock | 83 | $36.42 | $3K | |
| Bruce Booth | Open-market sale | Common Stock | 17 | $36.42 | $619 | |
| Bruce Booth | Open-market sale | Common Stock | 22,339 | $32.69 footnote F2 | $730K | |
| ||||||
| Bruce Booth | Open-market sale | Common Stock | 1,804 | $30.15 footnote F2 | $54K | |
| Bruce Booth | Open-market sale | Common Stock | 45,117 | $31.69 footnote F6 | $1.43M | |
| Bruce Booth | Open-market sale | Common Stock | 9,470 | $31.69 footnote F6 | $300K | |
| Bruce Booth | Open-market sale | Common Stock | 73,296 | $32.84 footnote F7 | $2.41M | |
| Bruce Booth | Open-market sale | Common Stock | 15,384 | $32.84 footnote F7 | $505K | |
| Bruce Booth | Open-market sale | Common Stock | 12,888 | $33.38 footnote F8 | $430K | |
| Bruce Booth | Open-market sale | Common Stock | 2,705 | $33.38 footnote F8 | $90K | |
| Bruce Booth | Open-market sale | Common Stock | 28,821 | $32.10 footnote F9 | $925K | |
| Bruce Booth | Open-market sale | Common Stock | 6,049 | $32.10 footnote F9 | $194K | |
| Bruce Booth | Open-market sale | Common Stock | 21,451 | $32.71 footnote F10 | $702K | |
| Bruce Booth | Open-market sale | Common Stock | 4,503 | $32.71 footnote F10 | $147K | |
| Bruce Booth | Open-market sale | Common Stock | 248 | $33.47 footnote F11 | $8K | |
| Bruce Booth | Open-market sale | Common Stock | 52 | $33.47 footnote F11 | $2K | |
| Bruce Booth | Open-market sale | Common Stock | 20,485 | $31.79 footnote F12 | $651K | |
| Bruce Booth | Open-market sale | Common Stock | 4,300 | $31.79 footnote F12 | $137K | |
| Bruce Booth | Open-market sale | Common Stock | 25,788 | $32.33 footnote F13 | $834K | |
| Bruce Booth | Open-market sale | Common Stock | 5,412 | $32.33 footnote F13 | $175K | |
| Bruce Booth | Open-market sale | Common Stock | 8,596 | $30.15 footnote F2 | $259K | |
| ||||||
| Michael Cloonan - Officer | Option exercise | Common Stock | 14,775 | $6.11 | $90K | |
| Michael Cloonan - Officer | Open-market sale | Common Stock | 14,775 | $31.11 footnote F2 | $460K | |
| Michael Cloonan - Officer | Option exercise | Common Stock | 10,225 | $6.11 | $62K | |
| Michael Cloonan - Officer | Open-market sale | Common Stock | 10,225 | $31.46 footnote F3 | $322K | |
| Michael Cloonan - Officer | Option exercise | Common Stock | 200 | $6.11 | $1K | |
| Michael Cloonan - Officer | Open-market sale | Common Stock | 200 | $34.00 | $7K | |
| Michael Cloonan - Officer | Option exercise | Non-Qualified Stock Option (right to buy) | 14,775 | $0.00 | - | |
| Michael Cloonan - Officer | Option exercise | Non-Qualified Stock Option (right to buy) | 10,225 | $0.00 | - | |
| Michael Cloonan - Officer | Option exercise | Non-Qualified Stock Option (right to buy) | 200 | $0.00 | - | |
| ||||||
| Bruce Booth | Open-market sale | Common Stock | 16,727 | $29.98 footnote F2 | $501K | |
| Bruce Booth | Open-market sale | Common Stock | 3,511 | $29.98 footnote F2 | $105K | |
| Bruce Booth | Open-market sale | Common Stock | 44,048 | $30.32 footnote F6 | $1.34M | |
| Bruce Booth | Open-market sale | Common Stock | 9,245 | $30.32 footnote F6 | $280K | |
| Bruce Booth | Open-market sale | Common Stock | 4,082 | $31.03 | $127K | |
| Bruce Booth | Open-market sale | Common Stock | 857 | $31.03 | $27K | |
| Bruce Booth | Open-market sale | Common Stock | 501 | $29.95 | $15K | |
| Bruce Booth | Open-market sale | Common Stock | 105 | $29.95 | $3K | |
| Bruce Booth | Open-market sale | Common Stock | 65,726 | $30.37 footnote F7 | $2.00M | |
| Bruce Booth | Open-market sale | Common Stock | 13,795 | $30.37 footnote F7 | $419K | |
| Bruce Booth | Open-market sale | Common Stock | 30,032 | $31.12 footnote F8 | $935K | |
| Bruce Booth | Open-market sale | Common Stock | 6,303 | $31.12 footnote F8 | $196K | |
| ||||||
| Bruce Booth | Open-market sale | Common Stock | 31,198 | $30.00 footnote F2 | $936K | |
| Bruce Booth | Open-market sale | Common Stock | 6,548 | $30.00 footnote F2 | $196K | |
| Bruce Booth | Open-market sale | Common Stock | 9,753 | $29.95 footnote F6 | $292K | |
| Bruce Booth | Open-market sale | Common Stock | 2,047 | $29.95 footnote F6 | $61K | |
| ||||||
 Caroline Stark Beer - Officer | Grant or award | Non-Qualified Stock Option (right to buy) | 255,000 | $0.00 | - | |
| Michael Cloonan - Officer | Option exercise | Common Stock | 17,207 | $6.11 | $105K | |
| Michael Cloonan - Officer | Open-market sale | Common Stock | 17,207 | $28.85 | $496K | |
| Michael Cloonan - Officer | Option exercise | Common Stock | 7,793 | $6.11 | $48K | |
| Michael Cloonan - Officer | Open-market sale | Common Stock | 7,793 | $29.70 | $231K | |
| Michael Cloonan - Officer | Option exercise | Non-Qualified Stock Option (right to buy) | 17,207 | $0.00 | - | |
| Michael Cloonan - Officer | Option exercise | Non-Qualified Stock Option (right to buy) | 7,793 | $0.00 | - | |
| Bruce Booth | Open-market sale | Common Stock | 54,637 | $30.09 | $1.64M | |
| Bruce Booth | Open-market sale | Common Stock | 11,468 | $30.09 | $345K | |
| Bruce Booth | Open-market sale | Common Stock | 10,239 | $30.06 | $308K | |
| Bruce Booth | Open-market sale | Common Stock | 2,149 | $30.06 | $65K | |
| Bruce Booth | Open-market sale | Common Stock | 165 | $29.95 | $5K | |
| Bruce Booth | Open-market sale | Common Stock | 35 | $29.95 | $1K | |
| Jennifer Fitzpatrick - Officer | Option exercise | Common Stock | 10,250 | $6.11 | $63K | |
| Jennifer Fitzpatrick - Officer | Open-market sale | Common Stock | 10,250 | $23.12 | $237K | |
| Jennifer Fitzpatrick - Officer | Option exercise | Non-Qualified Stock Option (right to buy) | 10,250 | $0.00 | - | |
| Elena Ridloff - Officer | Open-market sale | Common Stock | 748 | $25.18 | $19K | |
| Elena Ridloff - Officer | Open-market sale | Common Stock | 8,836 | $25.08 | $222K | |
| Elena Ridloff - Officer | Open-market sale | Common Stock | 3,700 | $25.13 | $93K | |
| Elena Ridloff - Officer | Open-market sale | Common Stock | 3,618 | $25.10 | $91K | |
| Elena Ridloff - Officer | Open-market sale | Common Stock | 16,098 | $25.97 | $418K | |
| Michael Cloonan - Officer | Option exercise | Common Stock | 17,574 | $6.11 | $107K | |
| Michael Cloonan - Officer | Open-market sale | Common Stock | 17,574 | $24.96 | $439K | |
| Michael Cloonan - Officer | Option exercise | Common Stock | 7,426 | $6.11 | $45K | |
| Michael Cloonan - Officer | Open-market sale | Common Stock | 7,426 | $25.01 | $186K | |
| Michael Cloonan - Officer | Option exercise | Non-Qualified Stock Option (right to buy) | 17,574 | $0.00 | - | |
| Michael Cloonan - Officer | Option exercise | Non-Qualified Stock Option (right to buy) | 7,426 | $0.00 | - | |
| Michael Cloonan - Officer | Option exercise | Common Stock | 25,000 | $6.11 | $153K | |
| Michael Cloonan - Officer | Open-market sale | Common Stock | 25,000 | $22.75 | $569K | |
| Michael Cloonan - Officer | Option exercise | Non-Qualified Stock Option (right to buy) | 25,000 | $0.00 | - | |
| Elena Ridloff - Officer | Open-market sale | Common Stock | 34,500 | $21.08 | $727K | |
| Elena Ridloff - Officer | Open-market sale | Common Stock | 17,500 | $22.69 | $397K | |
| TPG GP A, LLC - 10% Owner | Open-market purchase | Common Stock | 60,000 | $15.84 | $950K | |
Item 2.05, 5.02, 8.01, 9.01
Item 8.01, 9.01
Item 2.02, 9.01
Item 5.07
Recent SION Form 144 notices of proposed sale
3An insider files Form 144 before selling restricted or control stock. It announces a planned sale. If the sale goes ahead, it shows up later on a Form 4.
| Filed | Filer | Relationship | Shares | Market value | Notice |
|---|---|---|---|---|---|
| RA Capital Healthcare Fund, L.P. | Director, 10% Stockholder | 3,448,811 | $21.83M | View on EDGAR | |
| - | - | - |
SION insider trading FAQ
What is the latest insider trade for SION?
Sionna Therapeutics, Inc. (SION) had 5 insider filings in the last 90 days, with the most recent on 2026-09-21. The full record for SION runs to 56 Form 4 filings, the earliest from 2025-07-01. InsiderAlpha adds new Form 4, Form 144 and 8-K filings as they arrive from SEC EDGAR.
How many insiders are buying SION stock?
No insider purchases of SION were filed in the last 90 days. 1 purchase is on record for this company.
How many insiders are selling SION stock?
2 insider sales of SION were filed in the last 90 days, totaling $21.84M.
Where can I see SION SEC filings (Form 4, 10-K, 10-Q, 8-K)?
This page collects SION Form 4 insider transactions, Form 144 sale notices and 8-K filings in one place. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
More Health Care companies with insider activity
Recent insider filings
10The EDGAR links open each original Form 4, so you can check any number on this page against the filing it came from.
- - RA CAPITAL MANAGEMENT, L.P. view on EDGAR
- - Elena Ridloff view on EDGAR
- - Charlotte McKee view on EDGAR
- - Jennifer Fitzpatrick view on EDGAR
- - Michael Cloonan view on EDGAR
- - Peter A. Thompson view on EDGAR
- - ORBIMED ADVISORS LLC view on EDGAR
- - Jennifer Fitzpatrick view on EDGAR
- - Peter A. Thompson view on EDGAR
Related companies with recent insider activity
Learn more
- Insider selling: signal or noise?
- Why most insider sales are routine, and the few patterns worth a second look.
- Form 144 vs Form 4
- A Form 144 announces a planned sale; the Form 4 reports it after it happens.
- Insider activity in Health Care
- Where SION's peers are being bought and sold.
- Every recent Form 4
- The market-wide feed, updated as filings arrive from SEC EDGAR.
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