Silence Therapeutics PLC is a biotechnology company focused on discovering and developing novel molecules incorporating short-interfering ribonucleic acid or siRNA. Using its mRNAi GOLD platform, the company has generated siRNA product candidates both for its internal development pipeline as well as for out-licensed programs with third-party collaborators. Its wholly owned pipeline is focused on three therapeutic areas: cardiovascular disease, hematology, and rare diseases. The different product candidates in its pipeline are Divesiran (SLN124), a siRNA product candidate that has the potential to treat several hematological disorders; Zerlasiran (SLN360), being developed as a potential treatment to reduce cardiovascular issues; SLN-312; SLN-548; and multiple other programs.
https://www.silence-therapeutics.comSEC filings for SLN on EDGAR
| Form 4 transaction type | Transactions | Shares | Total value |
|---|---|---|---|
| Open-market sale | 17 | 7,028,694 | - |
9 Form 4 filings on record, the earliest from May 5, 2025, newest first.
| Date | Insider | Transaction | Security | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 2,792,826 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 100,000 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 50,000 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 3,500 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 800,000 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 382,000 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 470,820 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 605,174 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 120,000 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 60,000 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 100,000 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 330,072 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 169,928 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 79,180 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 50,000 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 50,082 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 865,112 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 20,000 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market purchase | American Depositary Shares | 20,000 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market sale | American Depositary Shares | 2,000 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market purchase | American Depositary Shares | 2,000 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market purchase | American Depositary Shares | 14,342 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market purchase | American Depositary Shares | 4,034 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market purchase | American Depositary Shares | 14,559 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market purchase | American Depositary Shares | 8,923 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market purchase | American Depositary Shares | 22,435 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market purchase | American Depositary Shares | 2,910 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market purchase | American Depositary Shares | 28,000 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market purchase | American Depositary Shares | 43,293 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market purchase | American Depositary Shares | 7,937 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market purchase | American Depositary Shares | 24,387 | - | - | |
| Richard Ian Griffiths - 10% Owner | Open-market purchase | American Depositary Shares | 30,133 | - | - | |
| Timothy McInerney | Grant or award | Share Option (Right to Buy) | 48,000 | $0.00 | - |
Silence Therapeutics plc (SLN) had 2 insider filings in the last 90 days, with the most recent on 2026-08-13. The full record for SLN runs to 9 Form 4 filings, the earliest from 2025-05-05. InsiderAlpha tracks every Form 4, Form 144, and 8-K filing in real time.
No insider purchases of SLN were filed in the last 90 days. 13 purchases are on record for this company.
17 insider sales of SLN were filed in the last 90 days.
This page tracks SLN Form 4 insider transactions, Form 144 sale notices, and 8-K material event disclosures in one timeline. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
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Every Form 4 below links to the original document on SEC EDGAR, so the numbers on this page can be checked against the filing they came from.
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