Q32 Bio Inc is a clinical-stage biotechnology company focused on developing novel biologics to restore healthy immune balance in patients with alopecia areata (AA) and other autoimmune and inflammatory diseases driven by immune dysfunction. Its product candidate, bempikibart (ADX 914), is a fully human anti-interleukin 7 receptor alpha (IL-7R) antagonist monoclonal antibody designed to block signaling mediated by interleukin 7 (IL 7) and thymic stromal lymphopoietin (TSLP) and re-regulate adaptive immune function. The company has completed two Phase 2a clinical trials evaluating bempikibart, SIGNAL AA Part A for the treatment of alopecia areata and SIGNAL AD for the treatment of atopic dermatitis (AD).
| Form 4 transaction type | Transactions | Shares | Total value |
|---|---|---|---|
| Open-market purchase | 4 | 3,750,000 | $30.00M |
| Open-market sale | 3 | 16,615 | $275K |
| Grant or award | 19 | 387,838 | |
| Option exercise | 2 | 107,042 |
Dollar totals are shown for open-market purchases and sales only. Grants, option exercises, gifts and tax withholding are reported by share count because they are not trades at a market price.
49 Form 4 filings on record, the earliest from Oct 10, 2024, newest first. Filing history page 1 of 2.
| Date | Insider | Transaction | Security | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jodie Pope Morrison - Officer | Open-market sale | Common Stock | 9,845 | $16.56 | $163K | |
| Lee Kalowski - Officer | Open-market sale | Common Stock | 3,972 | $16.56 | $66K | |
| Shelia M. Violette - Officer | Open-market sale | Common Stock | 2,798 | $16.56 | $46K | |
| Arthur Tzianabos | Grant or award | Stock Option (Right to Buy) | 10,826 | $0.00 | - | |
| Sven Ante Lundberg | Grant or award | Stock Option (Right to Buy) | 10,826 | $0.00 | - | |
| Kathleen Laporte | Grant or award | Stock Option (Right to Buy) | 10,826 | $0.00 | - | |
| Mark T. Iwicki | Grant or award | Stock Option (Right to Buy) | 10,826 | $0.00 | - | |
| Diyong Xu | Grant or award | Stock Option (Right to Buy) | 10,826 | $0.00 | - | |
| Grant or award | Stock Option (Right to Buy) | 10,826 | $0.00 | - | ||
| David S. Grayzel | Grant or award | Stock Option (Right to Buy) | 10,826 | $0.00 | - | |
| Grant or award | Stock Option (Right to Buy) | 10,826 | $0.00 | - | ||
| Shelia M. Violette - Officer | Grant or award | Common Stock | 37,500 | $0.00 | - | |
| Jodie Pope Morrison - Officer | Grant or award | Common Stock | 132,000 | $0.00 | - | |
| Lee Kalowski - Officer | Grant or award | Common Stock | 53,250 | $0.00 | - | |
| Option exercise | Common Stock | 53,521 | $2.80 | $150K | ||
| Option exercise | Stock Option (Right to Buy) | 53,521 | $0.00 | - | ||
| Kathleen Laporte | Grant or award | Stock Option (Right to Buy) | 9,810 | $0.00 | - | |
| Mark T. Iwicki | Grant or award | Stock Option (Right to Buy) | 9,810 | $0.00 | - | |
| Grant or award | Stock Option (Right to Buy) | 9,810 | $0.00 | - | ||
| Arthur Tzianabos | Grant or award | Stock Option (Right to Buy) | 9,810 | $0.00 | - | |
| David S. Grayzel | Grant or award | Stock Option (Right to Buy) | 9,810 | $0.00 | - | |
| Grant or award | Stock Option (Right to Buy) | 9,810 | $0.00 | - | ||
| Diyong Xu | Grant or award | Stock Option (Right to Buy) | 9,810 | $0.00 | - | |
| Sven Ante Lundberg | Grant or award | Stock Option (Right to Buy) | 9,810 | $0.00 | - | |
| Diyong Xu - Director | Open-market purchase | Common Stock | 1,250,000 | $8.00 | $10.00M | |
| Diyong Xu - Director | Open-market purchase | Common Stock | 625,000 | $8.00 | $5.00M | |
| ORBIMED ADVISORS LLC - Director | Open-market purchase | Common Stock | 1,250,000 | $8.00 | $10.00M | |
| ORBIMED ADVISORS LLC - Director | Open-market purchase | Common Stock | 625,000 | $8.00 | $5.00M | |
| Shelia M. Violette - Officer | Grant or award | Common Stock | 37,500 | $0.00 | - | |
| Lee Kalowski - Officer | Grant or award | Common Stock | 53,250 | $0.00 | - | |
| Jodie Pope Morrison - Officer | Grant or award | Common Stock | 132,000 | $0.00 | - | |
| Lee Kalowski - Officer | Open-market sale | Common Stock | 3,995 | $4.51 | $18K | |
| Jodie Pope Morrison - Officer | Open-market sale | Common Stock | 9,896 | $4.51 | $45K |
Q32 Bio Inc. (QTTB) had 25 insider filings in the last 90 days, with the most recent on 2026-08-27. The full record for QTTB runs to 49 Form 4 filings, the earliest from 2024-10-10. InsiderAlpha tracks every Form 4, Form 144, and 8-K filing in real time.
4 insider purchases of QTTB were filed in the last 90 days, totaling $30.00M.
3 insider sales of QTTB were filed in the last 90 days, totaling $275K.
This page tracks QTTB Form 4 insider transactions, Form 144 sale notices, and 8-K material event disclosures in one timeline. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
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Every Form 4 below links to the original document on SEC EDGAR, so the numbers on this page can be checked against the filing they came from.
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