Protagonist Therapeutics, Inc (PTGX)
Data as of , from SEC Form 4 filings.
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About Protagonist Therapeutics, Inc (PTGX)
Protagonist Therapeutics Inc is a biopharmaceutical company engaged in the discovery and development of peptide-based therapeutics using its proprietary technology platform. The company focuses on three therapeutic areas: inflammation and immunology, hematology, and metabolic diseases. Its pipeline includes clinical-stage and preclinical candidates such as rusfertide for polycythemia vera, icotrokinra for inflammatory diseases, and other programs targeting IL-17, obesity, and iron metabolism disorders, developed through internal research and strategic collaborations.
- NEWARK, CA
- 141
- 2016
- XNAS
https://www.protagonist-inc.comSEC filings for PTGX on EDGAR
PTGX Form 4 activity by transaction type, last 90 days
| Form 4 transaction type | Transactions | Shares | Total value |
|---|---|---|---|
| Open-market sale | 7 | 283,629 | $41.44M |
| Option exercise | 18 | 567,258 | |
| Bona-fide gift | 1 | 510 |
Dollar totals cover purchases and sales only (codes P and S). Grants, option exercises, gifts and tax withholding are counted in shares, because none of them is a trade at a market price.
PTGX insider transactions (Form 4)
11540 Form 4 filings on record, the earliest from Nov 19, 2024, newest first. Filing history page 1 of 2.
| Date | Insider | Transaction | Security | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Asif Ali - Officer | Option exercise | Common Stock | 15,650 | $19.19 | $300K | |
| Asif Ali - Officer | Option exercise | Common Stock | 9,229 | $38.98 | $360K | |
| Asif Ali - Officer | Option exercise | Common Stock | 28,438 | $23.42 | $666K | |
| Asif Ali - Officer | Option exercise | Common Stock | 5,312 | $12.17 | $65K | |
| Asif Ali - Officer | Open-market sale | Common Stock | 12,595 | $141.77 footnote F2 | $1.79M | |
| Asif Ali - Officer | Open-market sale | Common Stock | 46,034 | $141.78 footnote F3 | $6.53M | |
| Asif Ali - Officer | Option exercise | Stock Option (right to buy) | 9,229 | $0.00 | - | |
| Asif Ali - Officer | Option exercise | Stock Option (right to buy) | 28,438 | $0.00 | - | |
| Asif Ali - Officer | Option exercise | Stock Option (right to buy) | 15,650 | $0.00 | - | |
| Asif Ali - Officer | Option exercise | Stock Option (right to buy) | 5,312 | $0.00 | - | |
| ||||||
| Dinesh V. Ph D. Patel - Officer | Option exercise | Common Stock | 54,174 | $21.58 | $1.17M | |
| Dinesh V. Ph D. Patel - Officer | Open-market sale | Common Stock | 54,174 | $145.87 footnote F2 | $7.90M | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Common Stock | 63,548 | $21.58 | $1.37M | |
| Dinesh V. Ph D. Patel - Officer | Open-market sale | Common Stock | 63,548 | $146.18 footnote F3 | $9.29M | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Common Stock | 7,278 | $21.58 | $157K | |
| Dinesh V. Ph D. Patel - Officer | Open-market sale | Common Stock | 7,278 | $144.10 footnote F4 | $1.05M | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Stock Option (right to buy) | 54,174 | $0.00 | - | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Stock Option (right to buy) | 63,548 | $0.00 | - | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Stock Option (right to buy) | 7,278 | $0.00 | - | |
| ||||||
| Dinesh V. Ph D. Patel - Officer | Gift | Common Stock | 510 | $0.00 | - | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Common Stock | 65,761 | $21.58 | $1.42M | |
| Dinesh V. Ph D. Patel - Officer | Open-market sale | Common Stock | 65,761 | $149.11 footnote F2 | $9.81M | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Common Stock | 34,239 | $21.58 | $739K | |
| Dinesh V. Ph D. Patel - Officer | Open-market sale | Common Stock | 34,239 | $148.52 footnote F3 | $5.09M | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Stock Option (right to buy) | 65,761 | $0.00 | - | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Stock Option (right to buy) | 34,239 | $0.00 | - | |
| ||||||
| William D. Waddill - Director | Option exercise | Common Stock | 9,000 | $16.54 | $149K | |
| William D. Waddill - Director | Open-market sale | Common Stock | 9,000 | $117.94 footnote F2 | $1.06M | |
| William D. Waddill - Director | Option exercise | Stock Option (right to buy) | 9,000 | $0.00 | - | |
| ||||||
| William D. Waddill - Director | Option exercise | Common Stock | 3,000 | $11.80 | $35K | |
| William D. Waddill - Director | Option exercise | Common Stock | 6,000 | $16.54 | $99K | |
| William D. Waddill - Director | Open-market sale | Common Stock | 9,000 | $107.68 footnote F2 | $969K | |
| William D. Waddill - Director | Option exercise | Stock Option (right to buy) | 3,000 | $0.00 | - | |
| William D. Waddill - Director | Option exercise | Stock Option (right to buy) | 6,000 | $0.00 | - | |
| ||||||
| William D. Waddill - Director | Open-market sale | Common Stock | 9,000 | $99.64 | $897K | |
| William D. Waddill - Director | Option exercise | Common Stock | 9,000 | $11.80 | $106K | |
| William D. Waddill - Director | Option exercise | Stock Option (right to buy) | 9,000 | $0.00 | - | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Common Stock | 75,000 | $21.58 | $1.62M | |
| Dinesh V. Ph D. Patel - Officer | Open-market sale | Common Stock | 75,000 | $100.12 | $7.51M | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Stock Option (right to buy) | 75,000 | $0.00 | - | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Common Stock | 75,000 | $21.58 | $1.62M | |
| Dinesh V. Ph D. Patel - Officer | Open-market sale | Common Stock | 75,000 | $100.12 footnote F1 | $7.51M | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Stock Option (right to buy) | 75,000 | $0.00 | - | |
| ||||||
 Bryan Giraudo - Director | Option exercise | Common Stock | 12,000 | $6.98 | $84K | |
| Bryan Giraudo - Director | Open-market sale | Common Stock | 6,000 | $100.00 | $600K | |
| Bryan Giraudo - Director | Open-market sale | Common Stock | 5,130 | $100.00 | $513K | |
| Bryan Giraudo - Director | Option exercise | Common Stock | 24,000 | $6.45 | $155K | |
| Bryan Giraudo - Director | Open-market sale | Common Stock | 36,000 | $100.14 footnote F2 | $3.61M | |
| Bryan Giraudo - Director | Open-market sale | Common Stock | 12,000 | $100.07 | $1.20M | |
| Bryan Giraudo - Director | Option exercise | Stock Option (right to buy) | 24,000 | $0.00 | - | |
| Bryan Giraudo - Director | Option exercise | Stock Option (right to buy) | 12,000 | $0.00 | - | |
| ||||||
| Dinesh V. Ph D. Patel - Officer | Gift | Common Stock | 1,460 | $0.00 | - | |
| Asif Ali - Officer | Open-market sale | Common Stock | 1,750 footnote F1 | $105.47 | $185K | |
| ||||||
| Arturo Md Molina - Officer | Option exercise | Common Stock | 15,000 | $8.04 | $121K | |
| Arturo Md Molina - Officer | Open-market sale | Common Stock | 15,000 | $104.79 footnote F1 | $1.57M | |
| Arturo Md Molina - Officer | Option exercise | Stock Option (right to buy) | 15,000 | $0.00 | - | |
| ||||||
| Harold E. Selick - Director | Option exercise | Common Stock | 24,000 | $12.88 | $309K | |
| Harold E. Selick - Director | Open-market sale | Common Stock | 24,000 | $105.00 | $2.52M | |
| Harold E. Selick - Director | Option exercise | Stock Option (right to buy) | 24,000 | $0.00 | - | |
| Asif Ali - Officer | Option exercise | Common Stock | 5,265 | $12.17 | $64K | |
| Asif Ali - Officer | Option exercise | Common Stock | 19,500 | $19.19 | $374K | |
| Asif Ali - Officer | Open-market sale | Common Stock | 24,765 | $104.24 footnote F2 | $2.58M | |
| Asif Ali - Officer | Option exercise | Stock Option (right to buy) | 19,500 | $0.00 | - | |
| Asif Ali - Officer | Option exercise | Stock Option (right to buy) | 5,265 | $0.00 | - | |
| ||||||
| Dinesh V. Ph D. Patel - Officer | Option exercise | Common Stock | 59 | $8.58 | $506 | |
| Dinesh V. Ph D. Patel - Officer | Open-market sale | Common Stock | 59 | $101.00 | $6K | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Common Stock | 54,641 | $8.58 | $469K | |
| Dinesh V. Ph D. Patel - Officer | Open-market sale | Common Stock | 54,641 | $101.00 | $5.52M | |
| Dinesh V. Ph D. Patel - Officer | Gift | Common Stock | 50,000 | $0.00 | - | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Stock Option (right to buy) | 59 | $0.00 | - | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Stock Option (right to buy) | 54,641 | $0.00 | - | |
| Lewis T. Williams - Director | Option exercise | Common Stock | 18,000 | $10.84 | $195K | |
| Lewis T. Williams - Director | Open-market sale | Common Stock | 18,000 | $82.42 footnote F1 | $1.48M | |
| Lewis T. Williams - Director | Option exercise | Stock Option (right to buy) | 18,000 | $0.00 | - | |
| ||||||
| William D. Waddill - Director | Option exercise | Common Stock | 20,000 | $8.31 | $166K | |
| William D. Waddill - Director | Open-market sale | Common Stock | 20,000 | $83.68 footnote F1 | $1.67M | |
| William D. Waddill - Director | Option exercise | Stock Option (right to buy) | 20,000 | $0.00 | - | |
| ||||||
| Dinesh V. Ph D. Patel - Officer | Option exercise | Common Stock | 19,315 | $4.21 | $81K | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Common Stock | 10,685 | $4.21 | $45K | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Common Stock | 14,205 | $21.58 | $307K | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Common Stock | 4,068 | $21.58 | $88K | |
| Dinesh V. Ph D. Patel - Officer | Gift | Common Stock | 6,000 | $0.00 | - | |
| Dinesh V. Ph D. Patel - Officer | Open-market sale | Common Stock | 19,315 | $84.59 footnote F2 | $1.63M | |
| Dinesh V. Ph D. Patel - Officer | Open-market sale | Common Stock | 10,685 | $84.00 footnote F3 | $898K | |
| Dinesh V. Ph D. Patel - Officer | Open-market sale | Common Stock | 14,205 | $84.05 footnote F4 | $1.19M | |
| Dinesh V. Ph D. Patel - Officer | Open-market sale | Common Stock | 4,068 | $83.19 footnote F5 | $338K | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Stock Option (right to buy) | 19,315 | $0.00 | - | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Stock Option (right to buy) | 10,685 | $0.00 | - | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Stock Option (right to buy) | 14,205 | $0.00 | - | |
| Dinesh V. Ph D. Patel - Officer | Option exercise | Stock Option (right to buy) | 4,068 | $0.00 | - | |
| ||||||
| Asif Ali - Officer | Option exercise | Common Stock | 12,000 | $12.17 | $146K | |
| Asif Ali - Officer | Option exercise | Common Stock | 16,000 | $19.19 | $307K | |
| Asif Ali - Officer | Open-market sale | Common Stock | 28,000 | $83.13 footnote F2 | $2.33M | |
| Asif Ali - Officer | Open-market sale | Common Stock | 18,203 | $83.14 footnote F3 | $1.51M | |
| Asif Ali - Officer | Option exercise | Stock Option (right to buy) | 16,000 | $0.00 | - | |
| Asif Ali - Officer | Option exercise | Stock Option (right to buy) | 12,000 | $0.00 | - | |
| ||||||
| Arturo Md Molina - Officer | Option exercise | Common Stock | 5,000 | $8.04 | $40K | |
| Arturo Md Molina - Officer | Option exercise | Common Stock | 5,000 | $8.04 | $40K | |
| Arturo Md Molina - Officer | Open-market sale | Common Stock | 5,000 | $82.00 | $410K | |
| Arturo Md Molina - Officer | Open-market sale | Common Stock | 13,151 | $82.42 footnote F1 | $1.08M | |
| Arturo Md Molina - Officer | Open-market sale | Common Stock | 5,000 | $82.28 footnote F2 | $411K | |
| Arturo Md Molina - Officer | Option exercise | Stock Option (right to buy) | 5,000 | $0.00 | - | |
| Arturo Md Molina - Officer | Option exercise | Stock Option (right to buy) | 5,000 | $0.00 | - | |
| ||||||
| Arturo Md Molina - Officer | Open-market sale | Common Stock | 9,514 footnote F1 | $82.48 | $785K | |
| ||||||
| Dinesh V. Ph D. Patel - Officer | Open-market sale | Common Stock | 34,438 footnote F1 | $82.48 | $2.84M | |
| ||||||
| Asif Ali - Officer | Open-market sale | Common Stock | 8,588 footnote F1 | $82.48 | $708K | |
| ||||||
| Dinesh V. Ph D. Patel - Officer | Gift | Common Stock | 440 | $0.00 | - | |
| Arturo Md Molina - Officer | Open-market sale | Common Stock | 2,712 footnote F1 | $84.77 | $230K | |
| ||||||
| William D. Waddill - Director | Option exercise | Common Stock | 12,000 | $6.98 | $84K | |
| William D. Waddill - Director | Open-market sale | Common Stock | 4,000 | $69.25 | $277K | |
| William D. Waddill - Director | Open-market sale | Common Stock | 8,000 | $87.81 footnote F2 | $702K | |
| William D. Waddill - Director | Option exercise | Stock Option (right to buy) | 12,000 | $0.00 | - | |
| ||||||
| William D. Waddill - Director | Open-market sale | Common Stock | 4,000 | $64.25 | $257K | |
| Dinesh V. Ph D. Patel - Officer | Gift | Common Stock | 620 | $0.00 | - | |
| William D. Waddill - Director | Open-market sale | Common Stock | 4,000 | $59.25 | $237K | |
Item 2.02, 7.01, 9.01
Item 5.02, 5.07, 9.01
Item 2.02, 9.01
Item 2.02, 9.01
Recent PTGX Form 144 notices of proposed sale
3An insider files Form 144 before selling restricted or control stock. It announces a planned sale. If the sale goes ahead, it shows up later on a Form 4.
| Filed | Filer | Relationship | Shares | Market value | Notice |
|---|---|---|---|---|---|
| ASIF ALI | Officer | 58,629 | $8.26M | View on EDGAR | |
| Dinesh Patel | CEO | 225,000 |
PTGX insider trading FAQ
What is the latest insider trade for PTGX?
Protagonist Therapeutics, Inc (PTGX) had 4 insider filings in the last 90 days, with the most recent on 2026-10-02. The full record for PTGX runs to 40 Form 4 filings, the earliest from 2024-11-19. InsiderAlpha adds new Form 4, Form 144 and 8-K filings as they arrive from SEC EDGAR.
How many insiders are buying PTGX stock?
No insider purchases of PTGX were filed in the last 90 days.
How many insiders are selling PTGX stock?
7 insider sales of PTGX were filed in the last 90 days, totaling $41.44M.
Where can I see PTGX SEC filings (Form 4, 10-K, 10-Q, 8-K)?
This page collects PTGX Form 4 insider transactions, Form 144 sale notices and 8-K filings in one place. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
More Health Care companies with insider activity
Recent insider filings
10The EDGAR links open each original Form 4, so you can check any number on this page against the filing it came from.
- - Asif Ali view on EDGAR
- - Dinesh V. Ph D. Patel view on EDGAR
- - Dinesh V. Ph D. Patel view on EDGAR
- - Dinesh V. Ph D. Patel view on EDGAR
- - William D. Waddill view on EDGAR
- - William D. Waddill view on EDGAR
- - William D. Waddill view on EDGAR
- - Dinesh V. Ph D. Patel view on EDGAR
- - Dinesh V. Ph D. Patel view on EDGAR
Related companies with recent insider activity
Learn more
- Insider selling: signal or noise?
- Why most insider sales are routine, and the few patterns worth a second look.
- Form 144 vs Form 4
- A Form 144 announces a planned sale; the Form 4 reports it after it happens.
- Insider activity in Health Care
- Where PTGX's peers are being bought and sold.
- Every recent Form 4
- The market-wide feed, updated as filings arrive from SEC EDGAR.
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