Profile
| Role | 10% Owner |
|---|---|
| Notability | 30/100 |
Updated Jul 16, 2026
Opaleye Management Inc. has filed 15 SEC Form 4 filings across 4 companies in the last 90 days — active on both sides. Lifetime open-market purchases: $20.32M. Lifetime open-market sales: $19.71M. Historical track record: 5/5 stars across 85 tracked purchases.
| Role | 10% Owner |
|---|---|
| Notability | 30/100 |
InsiderAlpha computes a forward-return-based score for every insider with enough Form 4 purchase history. The metrics below reflect realised performance after each tracked open-market purchase.
| InsiderAlpha rating | ★★★★★ (5/5) |
|---|---|
| Total purchases tracked | 85 |
| Purchases with forward-return data | 79 |
| 30-day win rate | 7722% |
| 90-day win rate | 7848% |
| Avg 5-day return | +321.06% |
| Avg 30-day return | +1649.60% |
| Avg 90-day return | +3493.33% |
| Best 30-day return | +6889.43% |
| Date | Ticker | Company | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-07-15 | SLGL | Sol-Gel Technologies Ltd. | P — Open-market purchase | 920 | $73.43 | $68K |
| 2026-07-15 | SLGL | Sol-Gel Technologies Ltd. | P — Open-market purchase | 775 | $73.89 | $57K |
| 2026-07-10 | SLGL | Sol-Gel Technologies Ltd. | P — Open-market purchase | 229 | $73.95 | $17K |
| 2026-07-10 | SLGL | Sol-Gel Technologies Ltd. | P — Open-market purchase | 300 | $73.69 | $22K |
| 2026-07-07 | ETON | Eton Pharmaceuticals, Inc. | S — Open-market sale | 6.7K | $38.37 | $257K |
| 2026-07-07 | ETON | Eton Pharmaceuticals, Inc. | S — Open-market sale | 20.0K | $38.37 | $767K |
| 2026-07-07 | ETON | Eton Pharmaceuticals, Inc. | S — Open-market sale | 10.0K | $38.00 | $380K |
| 2026-07-07 | ETON | Eton Pharmaceuticals, Inc. | S — Open-market sale | 25.0K | $37.39 | $935K |
| 2026-07-07 | ETON | Eton Pharmaceuticals, Inc. | S — Open-market sale | 65.0K | $37.39 | $2.43M |
| 2026-07-02 | SLGL | Sol-Gel Technologies Ltd. | P — Open-market purchase | 1.4K | $71.97 | $101K |
| 2026-07-02 | SLGL | Sol-Gel Technologies Ltd. | P — Open-market purchase | 312 | $71.99 | $22K |
| 2026-06-29 | ACOG | Alpha Cognition Inc. | P — Open-market purchase | 152.3K | $6.40 | $975K |
| 2026-06-29 | ACOG | Alpha Cognition Inc. | P — Open-market purchase | 197 | $6.50 | $1K |
| 2026-06-16 | ACOG | Alpha Cognition Inc. | P — Open-market purchase | 4.5K | $5.99 | $27K |
| 2026-06-16 | ACOG | Alpha Cognition Inc. | P — Open-market purchase | 273 | $5.93 | $2K |
| 2026-06-16 | ACOG | Alpha Cognition Inc. | P — Open-market purchase | 2.9K | $5.91 | $17K |
| 2026-06-11 | ACOG | Alpha Cognition Inc. | P — Open-market purchase | 5.9K | $5.99 | $35K |
| 2026-06-11 | ACOG | Alpha Cognition Inc. | P — Open-market purchase | 24.9K | $5.98 | $149K |
| 2026-06-09 | ACOG | Alpha Cognition Inc. | P — Open-market purchase | 10.1K | $5.83 | $59K |
| 2026-05-29 | ACOG | Alpha Cognition Inc. | P — Open-market purchase | 70.6K | $5.90 | $416K |
Opaleye Management Inc. is a corporate insider — currently tracked as 10% Owner of Sol-Gel Technologies Ltd. (SLGL). InsiderAlpha tracks every SEC Form 4 filing in real time.
15 primary Form 4 filings in the last 90 days, covering 4 companies.
Recorded transactions: 109 open-market purchases ($20.32M) and 33 open-market sales ($19.71M) across all tracked filings.
Across 85 tracked purchases, Opaleye Management Inc. averaged +1649.6% avg 30-day return with a 7722% 30-day win rate. InsiderAlpha rates the track record at 5/5 stars.
All Form 4 filings, transaction values, and 10b5-1 plan flags are listed on this page and updated in real time as new SEC EDGAR filings are processed.
Open the live Opaleye Management Inc. profile on InsiderAlpha for real-time alerts, AI-scored trade ideas, and full transaction history.