Spyre Therapeutics, Inc. (SYRE)
Latest SYRE Insider Trades
Jeffrey W. Albers - DirectorOpen-market sale$522K
About Spyre Therapeutics, Inc. (SYRE)
Spyre Therapeutics Inc is a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (IBD) and rheumatic diseases. Spyre's pipeline includes extended half-life antibodies targeting α4β7, TL1A, and IL-23 in development as monotherapies and pair-wise combinations. It has a single reportable segment, which is the development of biopharmaceutical products for the treatment of patients with IBD and other immune-mediated disease.
- WALTHAM, MA
- 112
- 2016
- XNAS
90-Day SEC Filing Activity
| Form 4 transaction type | Transactions | Shares | Total value |
|---|---|---|---|
| Open-market sale | 29 | 4,826,948 | $412.44M |
| Option exercise | 14 | 118,334 | |
| Other acquisition / disposition | 2 | 683,347 |
SYRE Insider Transactions (Form 4)
635 Form 4 filings on record, the earliest from Oct 1, 2024, newest first. Filing history page 2 of 2.
| Date | Insider | Transaction | Security | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Cameron Turtle - Officer | Open-market sale | Common Stock | 28,155 |
Recent SYRE Form 8-K Filings
5Recent SYRE Form 144 Notices of Proposed Sale
3A Form 144 is notice of an INTENDED sale, not a completed one. It often precedes the Form 4 that reports the trade actually happening.
| Filed | Filer | Relationship | Shares | Market value | Notice |
|---|---|---|---|---|---|
| JEFFREY ALBERS | Director | 5,000 | $517K | View on EDGAR | |
| SESSIONS, LLC | Director |
SYRE Insider Trading - FAQ
What is the latest insider trade for SYRE?
Spyre Therapeutics, Inc. (SYRE) had 12 insider filings in the last 90 days, with the most recent on 2026-08-11. The full record for SYRE runs to 35 Form 4 filings, the earliest from 2024-10-01. InsiderAlpha tracks every Form 4, Form 144, and 8-K filing in real time.
How many insiders are buying SYRE stock?
No insider purchases of SYRE were filed in the last 90 days.
How many insiders are selling SYRE stock?
29 insider sales of SYRE were filed in the last 90 days, totaling $412.44M.
Where can I see SYRE SEC filings (Form 4, 10-K, 10-Q, 8-K)?
This page tracks SYRE Form 4 insider transactions, Form 144 sale notices, and 8-K material event disclosures in one timeline. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
How can I follow SYRE insider buys?
Create a free InsiderAlpha account and press Watch on this page to add SYRE to your watchlist. A free account also opens the full scored daily plan with every past day and 3 months of price history. No card is required. Sign up at https://insideralpha.ai/register.
More Health Care Companies with Insider Activity
Recent Insider Filings
10Every Form 4 below links to the original document on SEC EDGAR, so the numbers on this page can be checked against the filing they came from.
- - Jeffrey W. Albers view on EDGAR
- - Scott L. Burrows view on EDGAR
- - Cameron Turtle view on EDGAR
- - Scott L. Burrows view on EDGAR
- - Sheldon Sloan view on EDGAR
- - Cameron Turtle view on EDGAR
- - Scott L. Burrows view on EDGAR
- - Fairmount Funds Management LLC view on EDGAR
- - Michael Thomas Henderson view on EDGAR
Related Companies - Recent Insider Activity
Learn More
- What is SEC Form 4?
- The filing insiders must submit within two business days of a trade, and how to read its transaction codes.
- Insider activity in Health Care
- Where SYRE's peers are being bought and sold.
- Every recent Form 4
- The full market-wide feed, updated as filings arrive from SEC EDGAR.
Track SYRE insider activity as it files
Real-time Form 4 alerts, AI-scored daily trade ideas and 10b5-1 plan flags.
