Oruka Therapeutics, Inc. (ORKA)
$89.32-$7.22 (-7.48%) Today
Oruka Therapeutics Inc a clinical-stage biopharmaceutical company focused on developing novel monoclonal antibody therapeutics for psoriasis (PsO) and other inflammatory and immunology (I&I) indications. Its programs are to treat and potentially modify disease by targeting mechanisms with efficacy and safety involved in disease pathology and the activity of pathogenic tissue-resident memory T cells (TRMs). Its program, ORKA-001, is designed to target the p19 subunit of interleukin-23 (IL-23p19) for the treatment of PsO. Its co-lead program, ORKA-002, is designed to target interleukin-17A and interleukin-17F (IL-17A/F) for the treatment of PsO, hidradenitis suppurativa (HS), psoriatic arthritis (PsA), and other conditions.
| Form 4 transaction type | Transactions | Shares | Total value |
|---|---|---|---|
| Open-market sale | 42 | 3,701,859 | $313.46M |
| Grant or award | 7 | 165,680 | |
| Option exercise | 30 | 214,916 | |
| Other acquisition / disposition | 2 | 3,596,051 |
Dollar totals are shown for open-market purchases and sales only. Grants, option exercises, gifts and tax withholding are reported by share count because they are not trades at a market price.
45 Form 4 filings on record, the earliest from Nov 21, 2024, newest first. Filing history page 1 of 2.
| Date | Insider | Transaction | Security | Shares | Price | Value |
|---|---|---|---|---|---|---|
 Larry Todd Edwards - Officer | Grant or award | Common Stock | 100,000 | $0.00 | - | |
| Larry Todd Edwards - Officer | Grant or award | Employee Stock Option (right to buy) | 20,000 | $0.00 | - | |
| Joana Goncalves - Officer | Option exercise | Common Stock | 3,500 | $6.84 | $24K | |
| Joana Goncalves - Officer | Option exercise | Common Stock | 3,500 | $7.80 | $27K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 900 | $109.65 | $99K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 300 | $110.52 | $33K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 3,320 | $112.01 | $372K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 2,480 | $112.56 | $279K | |
| Joana Goncalves - Officer | Option exercise | Employee Stock Option (right to buy) | 3,500 | $0.00 | - | |
| Joana Goncalves - Officer | Option exercise | Employee Warrant (right to buy) | 3,500 | $0.00 | - | |
| Paul T. Quinlan - Officer | Option exercise | Common Stock | 10,000 | $7.80 | $78K | |
| Paul T. Quinlan - Officer | Option exercise | Common Stock | 42,000 | $12.50 | $525K | |
| Paul T. Quinlan - Officer | Open-market sale | Common Stock | 3,630 | $106.05 | $385K | |
| Paul T. Quinlan - Officer | Open-market sale | Common Stock | 10,434 | $107.14 | $1.12M | |
| Paul T. Quinlan - Officer | Open-market sale | Common Stock | 14,696 | $107.97 | $1.59M | |
| Paul T. Quinlan - Officer | Open-market sale | Common Stock | 10,200 | $109.11 | $1.11M | |
| Paul T. Quinlan - Officer | Open-market sale | Common Stock | 9,193 | $110.00 | $1.01M | |
| Paul T. Quinlan - Officer | Open-market sale | Common Stock | 3,847 | $111.14 | $428K | |
| Paul T. Quinlan - Officer | Option exercise | Employee Warrant (right to buy) | 10,000 | $0.00 | - | |
| Paul T. Quinlan - Officer | Option exercise | Employee Stock Option (right to buy) | 42,000 | $0.00 | - | |
| Arjun Agarwal - Officer | Option exercise | Common Stock | 8,542 | $12.50 | $107K | |
| Arjun Agarwal - Officer | Option exercise | Common Stock | 1,458 | $34.39 | $50K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 2,100 | $104.67 | $220K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 2,132 | $105.57 | $225K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 1,268 | $106.63 | $135K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 2,142 | $107.71 | $231K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 2,358 | $108.46 | $256K | |
| Arjun Agarwal - Officer | Option exercise | Employee Stock Option (right to buy) | 8,542 | $0.00 | - | |
| Arjun Agarwal - Officer | Option exercise | Employee Stock Option (right to buy) | 1,458 | $0.00 | - | |
| Joana Goncalves - Officer | Option exercise | Common Stock | 3,500 | $6.84 | $24K | |
| Joana Goncalves - Officer | Option exercise | Common Stock | 3,500 | $7.80 | $27K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 400 | $84.37 | $34K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 2,497 | $85.86 | $214K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 3,803 | $86.68 | $330K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 300 | $87.25 | $26K | |
| Joana Goncalves - Officer | Option exercise | Employee Stock Option (right to buy) | 3,500 | $0.00 | - | |
| Joana Goncalves - Officer | Option exercise | Employee Warrant (right to buy) | 3,500 | $0.00 | - | |
| Arjun Agarwal - Officer | Option exercise | Common Stock | 8,541 | $12.50 | $107K | |
| Arjun Agarwal - Officer | Option exercise | Common Stock | 1,458 | $34.39 | $50K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 300 | $83.07 | $25K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 3,743 | $84.26 | $315K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 5,656 | $84.90 | $480K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 300 | $85.63 | $26K | |
| Arjun Agarwal - Officer | Option exercise | Employee Stock Option (right to buy) | 8,541 | $0.00 | - | |
| Arjun Agarwal - Officer | Option exercise | Employee Stock Option (right to buy) | 1,458 | $0.00 | - | |
| Fairmount Funds Management LLC - Director | Other | Common Stock | 3,553,410 | - | - | |
| Fairmount Funds Management LLC - Director | Open-market sale | Common Stock | 3,553,410 | $84.43 | $300.01M | |
| Fairmount Funds Management LLC - Director | Other | Series B Preferred Stock | 42,641 | $0.00 | - | |
| Laura Lee Sandler - Officer | Option exercise | Common Stock | 5,000 | $7.80 | $39K | |
| Laura Lee Sandler - Officer | Open-market sale | Common Stock | 2,237 | $93.85 | $210K | |
| Laura Lee Sandler - Officer | Open-market sale | Common Stock | 2,263 | $94.75 | $214K | |
| Laura Lee Sandler - Officer | Open-market sale | Common Stock | 500 | $95.47 | $48K | |
| Laura Lee Sandler - Officer | Option exercise | Employee Warrant (right to buy) | 5,000 | $0.00 | - | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 888 | $80.01 | $71K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 699 | $82.15 | $57K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 4,340 | $69.85 | $303K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 3,260 | $70.34 | $229K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 395 | $69.69 | $28K | |
| Arjun Agarwal - Officer | Option exercise | Employee Stock Option (right to buy) | 8,000 | $0.00 | - | |
| Arjun Agarwal - Officer | Option exercise | Employee Stock Option (right to buy) | 1,459 | $0.00 | - | |
| Arjun Agarwal - Officer | Option exercise | Common Stock | 1,459 | $34.39 | $50K | |
| Arjun Agarwal - Officer | Option exercise | Common Stock | 8,000 | $12.50 | $100K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 1,859 | $68.34 | $127K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 1,636 | $68.38 | $112K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 5,064 | $69.42 | $352K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 300 | $70.62 | $21K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 947 | $69.69 | $66K | |
| Joana Goncalves - Officer | Option exercise | Employee Stock Option (right to buy) | 3,500 | $0.00 | - | |
| Joana Goncalves - Officer | Option exercise | Employee Warrant (right to buy) | 3,500 | $0.00 | - | |
| Joana Goncalves - Officer | Option exercise | Common Stock | 3,500 | $7.80 | $27K | |
| Joana Goncalves - Officer | Option exercise | Common Stock | 3,500 | $6.84 | $24K | |
 Lawrence Otto Klein - Officer | Open-market sale | Common Stock | 1,729 | $69.69 | $120K | |
| Laura Lee Sandler - Officer | Open-market sale | Common Stock | 600 | $69.69 | $42K | |
| Paul T. Quinlan - Officer | Open-market sale | Common Stock | 733 | $69.69 | $51K | |
 Carl Dambkowski - Director | Open-market sale | Common Stock | 12,583 | $70.11 | $882K | |
| Carl Dambkowski - Director | Open-market sale | Common Stock | 22,417 | $70.13 | $1.57M | |
| Carl Dambkowski - Director | Grant or award | Stock Option (right to buy) | 9,136 | $0.00 | - | |
 Samarth Kulkarni - Director | Grant or award | Stock Option (right to buy) | 9,136 | $0.00 | - | |
| Christopher Nathan Martin - Director | Grant or award | Stock Option (right to buy) | 9,136 | $0.00 | - | |
| Kristine M. Ball - Director | Grant or award | Stock Option (right to buy) | 9,136 | $0.00 | - | |
| Fairmount Funds Management LLC - Director | Grant or award | Stock Option (Right to Buy) | 9,136 | $0.00 | - | |
| Carl Dambkowski - Director | Option exercise | Common Stock | 38,689 | $6.84 | $265K | |
| Carl Dambkowski - Director | Option exercise | Common Stock | 11,904 | $7.80 | $93K | |
| Carl Dambkowski - Director | Option exercise | Common Stock | 11,667 | $11.77 | $137K | |
| Carl Dambkowski - Director | Open-market sale | Common Stock | 38,318 | $58.43 | $2.24M | |
| Carl Dambkowski - Director | Open-market sale | Common Stock | 53,447 | $59.10 | $3.16M | |
| Carl Dambkowski - Director | Open-market sale | Common Stock | 13,235 | $59.97 | $794K | |
| Carl Dambkowski - Director | Option exercise | Stock Option (right to buy) | 38,689 | $0.00 | - | |
| Carl Dambkowski - Director | Option exercise | Warrant (right to buy) | 11,904 | $0.00 | - | |
| Carl Dambkowski - Director | Option exercise | Stock Option (right to buy) | 11,667 | $0.00 | - | |
| Arjun Agarwal - Officer | Option exercise | Common Stock | 2,000 | $12.50 | $25K | |
| Arjun Agarwal - Officer | Option exercise | Common Stock | 5,833 | $34.39 | $201K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 4,190 | $58.34 | $244K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 4,600 | $59.19 | $272K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 800 | $60.34 | $48K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 700 | $61.16 | $43K | |
| Arjun Agarwal - Officer | Option exercise | Employee Stock Option (right to buy) | 2,000 | $0.00 | - | |
| Arjun Agarwal - Officer | Option exercise | Employee Stock Option (right to buy) | 5,833 | $0.00 | - | |
| Joana Goncalves - Officer | Option exercise | Common Stock | 3,500 | $6.84 | $24K | |
| Joana Goncalves - Officer | Option exercise | Common Stock | 3,500 | $7.80 | $27K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 4,800 | $61.56 | $295K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 2,100 | $62.42 | $131K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 100 | $63.52 | $6K | |
| Joana Goncalves - Officer | Option exercise | Employee Stock Option (right to buy) | 3,500 | $0.00 | - | |
| Joana Goncalves - Officer | Option exercise | Employee Warrant (right to buy) | 3,500 | $0.00 | - | |
| Laura Lee Sandler - Officer | Option exercise | Common Stock | 5,000 | $7.80 | $39K | |
| Laura Lee Sandler - Officer | Open-market sale | Common Stock | 2,200 | $62.58 | $138K | |
| Laura Lee Sandler - Officer | Open-market sale | Common Stock | 1,800 | $64.15 | $115K | |
| Laura Lee Sandler - Officer | Open-market sale | Common Stock | 300 | $65.10 | $20K | |
| Laura Lee Sandler - Officer | Open-market sale | Common Stock | 400 | $66.06 | $26K | |
| Laura Lee Sandler - Officer | Open-market sale | Common Stock | 200 | $67.16 | $13K | |
| Laura Lee Sandler - Officer | Open-market sale | Common Stock | 100 | $68.48 | $7K | |
| Laura Lee Sandler - Officer | Option exercise | Employee Warrant (right to buy) | 5,000 | $0.00 | - | |
| Joana Goncalves - Officer | Option exercise | Common Stock | 3,500 | $6.84 | $24K | |
| Joana Goncalves - Officer | Option exercise | Common Stock | 3,500 | $7.80 | $27K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 4,227 | $65.73 | $278K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 2,273 | $66.56 | $151K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 500 | $67.38 | $34K | |
| Joana Goncalves - Officer | Option exercise | Employee Stock Option (right to buy) | 3,500 | $0.00 | - | |
| Joana Goncalves - Officer | Option exercise | Employee Warrant (right to buy) | 3,500 | $0.00 | - | |
| Lawrence Otto Klein - Officer | Open-market sale | Common Stock | 1,729 | $41.30 | $71K | |
| Arjun Agarwal - Officer | Open-market sale | Common Stock | 395 | $41.30 | $16K | |
| Laura Lee Sandler - Officer | Open-market sale | Common Stock | 600 | $41.30 | $25K | |
| Joana Goncalves - Officer | Option exercise | Common Stock | 3,500 | $6.84 | $24K | |
| Joana Goncalves - Officer | Option exercise | Common Stock | 3,500 | $7.80 | $27K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 2,921 | $40.11 | $117K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 2,902 | $41.20 | $120K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 1,177 | $41.94 | $49K | |
| Joana Goncalves - Officer | Open-market sale | Common Stock | 641 | $41.30 | $26K | |
| Joana Goncalves - Officer | Option exercise | Employee Stock Option (right to buy) | 3,500 | $0.00 | - | |
| Joana Goncalves - Officer | Option exercise | Employee Warrant (right to buy) | 3,500 | $0.00 | - | |
| Paul T. Quinlan - Officer | Open-market sale | Common Stock | 733 | $41.30 | $30K |
A Form 144 is notice of an INTENDED sale, not a completed one. It often precedes the Form 4 that reports the trade actually happening.
| Filed | Filer | Relationship | Shares | Market value | Notice |
|---|---|---|---|---|---|
| PAUL QUINLAN | Officer | 71,000 | $7.68M | View on EDGAR | |
| - | - | - | - | View on EDGAR | |
| - | - | - | - | View on EDGAR |
Oruka Therapeutics, Inc. (ORKA) had 20 insider filings in the last 90 days, with the most recent on 2026-08-25. The full record for ORKA runs to 45 Form 4 filings, the earliest from 2024-11-21. InsiderAlpha tracks every Form 4, Form 144, and 8-K filing in real time.
No insider purchases of ORKA were filed in the last 90 days.
42 insider sales of ORKA were filed in the last 90 days, totaling $313.46M.
This page tracks ORKA Form 4 insider transactions, Form 144 sale notices, and 8-K material event disclosures in one timeline. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
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Every Form 4 below links to the original document on SEC EDGAR, so the numbers on this page can be checked against the filing they came from.
Real-time Form 4 alerts, AI-scored daily trade ideas and 10b5-1 plan flags.
