Updated Jul 16, 2026
LOSCALZO JOSEPH has filed 2 SEC Form 4 filings across 1 company in the last 90 days — selling. Lifetime open-market sales: $7.36M.

| Role | Director |
|---|---|
| Notability | 30/100 |
| Date | Ticker | Company | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-05-06 | IONS | IONIS PHARMACEUTICALS INC | S — Open-market sale | 17.8K | $75.58 | $1.34M |
| 2026-05-06 | IONS | IONIS PHARMACEUTICALS INC | S — Open-market sale | 59.5K | $74.90 | $4.46M |
| 2026-05-06 | IONS | IONIS PHARMACEUTICALS INC | M — Option exercise | 16.0K | $64.80 | $1.04M |
| 2026-05-06 | IONS | IONIS PHARMACEUTICALS INC | M — Option exercise | 12.0K | $60.20 | $722K |
| 2026-05-06 | IONS | IONIS PHARMACEUTICALS INC | M — Option exercise | 16.0K | $42.88 | $686K |
| 2026-05-06 | IONS | IONIS PHARMACEUTICALS INC | M — Option exercise | 10.3K | $41.08 | $424K |
| 2026-05-06 | IONS | IONIS PHARMACEUTICALS INC | M — Option exercise | 12.0K | $40.05 | $481K |
| 2026-05-06 | IONS | IONIS PHARMACEUTICALS INC | M — Option exercise | 11.0K | $38.06 | $417K |
| 2026-03-17 | CYPH | CYPHERPUNK TECHNOLOGIES INC. | M — Option exercise | 94.0K | — | |
| 2026-03-17 | CYPH | CYPHERPUNK TECHNOLOGIES INC. | M — Option exercise | 74.7K | — | |
| 2026-03-05 | IONS | IONIS PHARMACEUTICALS INC | S — Open-market sale [10b5-1] | 200 | $80.00 | $16K |
| 2026-03-05 | IONS | IONIS PHARMACEUTICALS INC | M — Option exercise [10b5-1] | 200 | $38.06 | $8K |
| 2026-03-05 | IONS | IONIS PHARMACEUTICALS INC | S — Open-market sale [10b5-1] | 832 | $80.33 | $67K |
| 2026-03-05 | IONS | IONIS PHARMACEUTICALS INC | M — Option exercise [10b5-1] | 832 | $38.06 | $32K |
| 2025-09-03 | IONS | IONIS PHARMACEUTICALS INC | S — Open-market sale | 16.0K | $60.15 | $962K |
| 2025-09-03 | IONS | IONIS PHARMACEUTICALS INC | M — Option exercise | 16.0K | $24.42 | $391K |
| 2025-07-15 | IONS | IONIS PHARMACEUTICALS INC | M — Option exercise | 4.1K | $0.00 | |
| 2024-11-14 | IONS | IONIS PHARMACEUTICALS INC | S — Open-market sale [10b5-1] | 13.5K | $37.86 | $511K |
LOSCALZO JOSEPH is a corporate insider — currently tracked as Director of IONIS PHARMACEUTICALS INC (IONS). InsiderAlpha tracks every SEC Form 4 filing in real time.
2 primary Form 4 filings in the last 90 days, covering 1 company.
Recorded transactions: 0 open-market purchases () and 6 open-market sales ($7.36M) across all tracked filings.
All Form 4 filings, transaction values, and 10b5-1 plan flags are listed on this page and updated in real time as new SEC EDGAR filings are processed.
Open the live LOSCALZO JOSEPH profile on InsiderAlpha for real-time alerts, AI-scored trade ideas, and full transaction history.