Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
| Form 4 transaction type | Transactions | Shares | Total value |
|---|---|---|---|
| Open-market sale | 9 | 14,094 | $6.63M |
| Grant or award | 4 | 16,634 |
Dollar totals are shown for open-market purchases and sales only. Grants, option exercises, gifts and tax withholding are reported by share count because they are not trades at a market price.
119 Form 4 filings on record, the earliest from Oct 3, 2024, newest first. Filing history page 2 of 3.
| Date | Insider | Transaction | Security | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Carmen Bozic - Officer | Open-market sale | Common Stock | 2,329 | $450.95 | $1.05M | |
| Carmen Bozic - Officer | Open-market sale | Common Stock | 2,329 | $481.79 | $1.12M | |
| Open-market sale | Common Stock | 2,633 | $498.42 | $1.31M | ||
| Open-market sale | Common Stock | 2,437 | $475.30 | $1.16M | ||
| Joy Liu - Officer | Open-market sale | Common Stock | 892 | $495.96 | $442K | |
| Open-market sale | Common Stock | 400 | $479.75 | $192K | ||
| Open-market sale | Common Stock | 120 | $481.50 | $58K | ||
| Open-market sale | Common Stock | 240 | $482.84 | $116K | ||
| Open-market sale | Common Stock | 2,510 | $487.13 | $1.22M | ||
| Open-market sale | Common Stock | 2,520 | $493.29 | $1.24M | ||
| Open-market sale | Common Stock | 3,498 | $494.33 | $1.73M | ||
| Open-market sale | Common Stock | 15,580 | $495.38 | $7.72M | ||
| Open-market sale | Common Stock | 5,995 | $496.16 | $2.97M | ||
| Open-market sale | Common Stock | 1,725 | $496.95 | $857K | ||
| Open-market sale | Common Stock | 3,278 | $488.27 | $1.60M | ||
| Open-market sale | Common Stock | 460 | $489.32 | $225K | ||
| Open-market sale | Common Stock | 2,725 | $490.54 | $1.34M | ||
| Open-market sale | Common Stock | 949 | $491.30 | $466K | ||
| Carmen Bozic - Officer | Open-market sale | Common Stock | 2,329 | $480.31 | $1.12M | |
| Kristen Ambrose - Officer | Open-market sale | Common Stock | 357 | $483.36 | $173K | |
| Charles F. Wagner Jr. - Officer | Tax withholding / forfeiture | Common Stock | 1,744 | $485.11 | $846K | |
| Ourania Tatsis - Officer | Tax withholding / forfeiture | Common Stock | 1,627 | $485.11 | $789K | |
| Ourania Tatsis - Officer | Open-market sale | Common Stock | 260 | $486.35 | $126K | |
| Tax withholding / forfeiture | Common Stock | 1,518 | $485.11 | $736K | ||
| Open-market sale | Common Stock | 1,846 | $486.35 | $898K | ||
| Tax withholding / forfeiture | Common Stock | 873 | $485.11 | $424K | ||
| Open-market sale | Common Stock | 2,500 | $486.35 | $1.22M | ||
| Open-market sale | Common Stock | 2,410 | $489.00 | $1.18M | ||
| Jeffrey M. Leiden - Officer | Tax withholding / forfeiture | Common Stock | 3,547 | $485.11 | $1.72M | |
| Tax withholding / forfeiture | Common Stock | 4,981 | $485.11 | $2.42M | ||
| Mark E. Bunnage - Officer | Tax withholding / forfeiture | Common Stock | 582 | $485.11 | $282K | |
| Mark E. Bunnage - Officer | Open-market sale | Common Stock | 620 | $486.35 | $302K | |
| Carmen Bozic - Officer | Tax withholding / forfeiture | Common Stock | 1,453 | $485.11 | $705K | |
| Tax withholding / forfeiture | Common Stock | 1,144 | $485.11 | $555K | ||
| Open-market sale | Common Stock | 945 | $486.35 | $460K | ||
| Edward Morrow Atkinson III - Officer | Tax withholding / forfeiture | Common Stock | 1,627 | $485.11 | $789K | |
| Edward Morrow Atkinson III - Officer | Open-market sale | Common Stock | 668 | $486.35 | $325K | |
| Kristen Ambrose - Officer | Tax withholding / forfeiture | Common Stock | 546 | $485.11 | $265K | |
| Kristen Ambrose - Officer | Open-market sale | Common Stock | 223 | $486.35 | $108K | |
| Option exercise | Common Stock | 23,479 | $155.57 | $3.65M | ||
| Option exercise | Common Stock | 25,026 | $187.53 | $4.69M | ||
| Open-market sale | Common Stock | 920 | $463.91 | $427K | ||
| Open-market sale | Common Stock | 2,730 | $465.05 | $1.27M | ||
| Open-market sale | Common Stock | 1,848 | $465.80 | $861K | ||
| Open-market sale | Common Stock | 10,263 | $467.75 | $4.80M | ||
| Open-market sale | Common Stock | 19,662 | $468.57 | $9.21M | ||
| Open-market sale | Common Stock | 7,241 | $469.61 | $3.40M | ||
| Open-market sale | Common Stock | 11,712 | $470.54 | $5.51M | ||
| Open-market sale | Common Stock | 4,237 | $471.43 | $2.00M | ||
| Option exercise | Stock Option (Right to Buy) | 23,479 | $0.00 | - | ||
| Option exercise | Stock Option (Right to Buy) | 25,026 | $0.00 | - | ||
| Charles F. Wagner Jr. - Officer | Tax withholding / forfeiture | Common Stock | 2,294 | $483.75 | $1.11M | |
| Charles F. Wagner Jr. - Officer | Grant or award | Common Stock | 7,365 | $0.00 | - | |
| Ourania Tatsis - Officer | Tax withholding / forfeiture | Common Stock | 2,294 | $483.75 | $1.11M | |
| Ourania Tatsis - Officer | Open-market sale | Common Stock | 368 | $473.68 | $174K | |
| Ourania Tatsis - Officer | Grant or award | Common Stock | 5,789 | $0.00 | - | |
| Ourania Tatsis - Officer | Open-market sale | Common Stock | 609 | $489.46 | $298K | |
| Tax withholding / forfeiture | Common Stock | 2,140 | $483.75 | $1.04M | ||
| Grant or award | Common Stock | 5,789 | $0.00 | - | ||
| Tax withholding / forfeiture | Common Stock | 1,148 | $483.75 | $555K | ||
| Grant or award | Common Stock | 4,962 | $0.00 | - | ||
| Jeffrey M. Leiden - Officer | Tax withholding / forfeiture | Common Stock | 2,964 | $483.75 | $1.43M | |
| Jeffrey M. Leiden - Officer | Grant or award | Common Stock | 8,269 | $0.00 | - | |
| Tax withholding / forfeiture | Common Stock | 6,554 | $483.75 | $3.17M | ||
| Grant or award | Common Stock | 16,326 | $0.00 | - | ||
| Mark E. Bunnage - Officer | Tax withholding / forfeiture | Common Stock | 1,110 | $483.75 | $537K | |
| Mark E. Bunnage - Officer | Grant or award | Common Stock | 2,584 | $0.00 | - | |
| Mark E. Bunnage - Officer | Open-market sale | Common Stock | 2,437 | $489.46 | $1.19M | |
| Mark E. Bunnage - Officer | Open-market sale | Common Stock | 1,182 | $473.68 | $560K | |
| Carmen Bozic - Officer | Tax withholding / forfeiture | Common Stock | 1,912 | $483.75 | $925K | |
| Carmen Bozic - Officer | Grant or award | Common Stock | 5,375 | $0.00 | - | |
| Tax withholding / forfeiture | Common Stock | 1,505 | $483.75 | $728K | ||
| Grant or award | Common Stock | 4,135 | $0.00 | - | ||
| Open-market sale | Common Stock | 2,476 | $489.46 | $1.21M | ||
| Open-market sale | Common Stock | 1,244 | $473.68 | $589K | ||
| Edward Morrow Atkinson III - Officer | Tax withholding / forfeiture | Common Stock | 1,530 | $483.75 | $740K | |
| Edward Morrow Atkinson III - Officer | Grant or award | Common Stock | 4,962 | $0.00 | - | |
| Edward Morrow Atkinson III - Officer | Open-market sale | Common Stock | 2,031 | $489.46 | $994K | |
| Edward Morrow Atkinson III - Officer | Open-market sale | Common Stock | 817 | $473.68 | $387K |
A Form 144 is notice of an INTENDED sale, not a completed one. It often precedes the Form 4 that reports the trade actually happening.
| Filed | Filer | Relationship | Shares | Market value | Notice |
|---|---|---|---|---|---|
| Bruce I. Sachs | Director | 1,210 | $663K | View on EDGAR | |
| - | - | - | - | View on EDGAR | |
| - | - | - | - | View on EDGAR |
VERTEX PHARMACEUTICALS INC / MA (VRTX) had 13 insider filings in the last 90 days, with the most recent on 2026-07-23. The full record for VRTX runs to 119 Form 4 filings, the earliest from 2024-10-03. InsiderAlpha tracks every Form 4, Form 144, and 8-K filing in real time.
No insider purchases of VRTX were filed in the last 90 days. 4 purchases are on record for this company.
9 insider sales of VRTX were filed in the last 90 days, totaling $6.63M.
This page tracks VRTX Form 4 insider transactions, Form 144 sale notices, and 8-K material event disclosures in one timeline. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
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Every Form 4 below links to the original document on SEC EDGAR, so the numbers on this page can be checked against the filing they came from.
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