Scholar Rock Holding Corp (SRRK)

Data as of Oct 27, 2026, from SEC Form 4 filings.

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Latest SRRK insider trades

Srinivas Akkaraju - Director
Open-market purchase$1.94M
Oct 23, 2026

About Scholar Rock Holding Corp (SRRK)

Scholar Rock Holding Corp files with the SEC under CIK 0001727196 and is classified as biological products (no diagnostic substances). We track it alongside the rest of the Health Care sector.

Sector: Health Care

SEC filings for SRRK on EDGAR

SRRK Form 4 activity by transaction type, last 90 days

Form 4 transaction type	Transactions	Shares	Total value
Open-market purchase	6	289,470	$12.00M
Bona-fide gift	2	84,686

Dollar totals cover purchases and sales only (codes P and S). Grants, option exercises, gifts and tax withholding are counted in shares, because none of them is a trade at a market price.

SRRK insider transactions (Form 4)

67 Form 4 filings on record, the earliest from Oct 7, 2024, newest first. Filing history page 2 of 3.

Traded	Insider	Transaction	Security	Shares	Price	Value
Feb 9, 2026	David Hallal - Officer	Grant or award	Common Stock	128,004^{footnote F1}	$0.00	-
Footnote F1 (shares): Represents restricted stock units ("RSUs") subject to time-based vesting conditions. Each RSU represents the contingent right to receive, upon vesting of the RSU, one share of the Issuer's common stock. The shares subject to this RSU vest in four annual installments over four… Full note on SEC EDGAR
Feb 9, 2026	Keith Woods - Officer	Grant or award	Common Stock	47,021^{footnote F1}	$0.00	-
Footnote F1 (shares): Represents restricted stock units ("RSUs") subject to time-based vesting conditions. Each RSU represents the contingent right to receive, upon vesting of the RSU, one share of the Issuer's common stock. The shares subject to this RSU vest in four annual installments over four… Full note on SEC EDGAR
Dec 11, 2025	Invus Global Management, LLC	Other	Common Stock	1,575,008	$7.35	$11.58M
Dec 11, 2025	Invus Global Management, LLC	Other	Warrant (right to buy)	1,575,008	$0.00	-
Jan 22, 2026	Mo Qatanani - Officer	Open-market sale	Common Stock	2,119^{footnote F1}	$45.87^{footnote F2}	$97K
Jan 22, 2026	Mo Qatanani - Officer	Open-market sale	Common Stock	12,779^{footnote F1}	$46.85^{footnote F4}	$599K
Footnote F1 (shares): This transaction was effected by the Reporting Person pursuant to a Rule 10b5-1 trading plan adopted on March 31, 2025. Footnote F2 (price): The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $45.43 to $46.42, inclusive. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon… Full note on SEC EDGAR Footnote F4 (price): The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $46.43 to $47.31, inclusive. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon… Full note on SEC EDGAR
Jan 16, 2026	Mo Qatanani - Officer	Open-market sale	Common Stock	8,406^{footnote F1}	$44.48	$374K
Footnote F1 (shares): Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the vesting of restricted stock units ("RSU") on January 15, 2026. This sale is mandated by the Issuer's election under its equity incentive… Full note on SEC EDGAR
Jan 16, 2026	Caryn Parlavecchio - Officer	Open-market sale	Common Stock	6,600^{footnote F1}	$44.48	$294K
Footnote F1 (shares): Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the vesting of restricted stock units ("RSU") on January 15, 2026. This sale is mandated by the Issuer's election under its equity incentive… Full note on SEC EDGAR
Jan 16, 2026	Jing L. Marantz - Officer	Open-market sale	Common Stock	5,798^{footnote F1}	$44.48	$258K
Footnote F1 (shares): Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the vesting of restricted stock units ("RSU") on January 15, 2026. This sale is mandated by the Issuer's election under its equity incentive… Full note on SEC EDGAR
Jan 16, 2026	Junlin Ho - Officer	Open-market sale	Common Stock	8,016^{footnote F1}	$44.48	$357K
Footnote F1 (shares): Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the vesting of restricted stock units ("RSU") on January 15, 2026. This sale is mandated by the Issuer's election under its equity incentive… Full note on SEC EDGAR
Jan 14, 2026	Mo Qatanani - Officer	Option exercise	Common Stock	1,407^{footnote F1}	$18.08	$25K
Jan 14, 2026	Mo Qatanani - Officer	Option exercise	Common Stock	321^{footnote F1}	$7.62	$2K
Jan 14, 2026	Mo Qatanani - Officer	Option exercise	Common Stock	2,813^{footnote F1}	$10.00	$28K
Jan 14, 2026	Mo Qatanani - Officer	Option exercise	Common Stock	5,893^{footnote F1}	$15.75	$93K
Jan 14, 2026	Mo Qatanani - Officer	Option exercise	Common Stock	2,678^{footnote F1}	$35.15	$94K
Jan 14, 2026	Mo Qatanani - Officer	Open-market sale	Common Stock	13,112^{footnote F1}	$45.20^{footnote F7}	$593K
Jan 14, 2026	Mo Qatanani - Officer	Option exercise	Stock Option (Right to Buy)	1,407	$0.00	-
Jan 14, 2026	Mo Qatanani - Officer	Option exercise	Stock Option (Right to Buy)	321	$0.00	-
Jan 14, 2026	Mo Qatanani - Officer	Option exercise	Stock Option (Right to Buy)	2,813	$0.00	-
Jan 14, 2026	Mo Qatanani - Officer	Option exercise	Stock Option (Right to Buy)	5,893	$0.00	-
Jan 14, 2026	Mo Qatanani - Officer	Option exercise	Stock Option (Right to Buy)	2,678	$0.00	-
Footnote F1 (shares): This transaction was effected by the Reporting Person pursuant to a Rule 10b5-1 trading plan adopted on March 31, 2025. Footnote F7 (price): The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $45.00 to $45.45, inclusive. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon… Full note on SEC EDGAR
Jan 13, 2026	Vikas Sinha - Officer	Open-market sale	Common Stock	16,755^{footnote F1,F2}	$42.70	$715K
Footnote F1 (shares): Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the vesting of restricted stock units subject to performance-and time-based vesting conditions ("PSUs"). The sale is mandated by the Issuer's… Full note on SEC EDGAR Footnote F2 (shares): (continued) The shares vested pursuant to awards that were granted on April 27, 2025. 50,000 shares subject to this PSU vested on January 12, 2026, with an additional 50,000 shares scheduled to vest on April 27, 2027 and the remaining shares vesting in tranches of a combination… Full note on SEC EDGAR
Jan 13, 2026	Keith Woods - Officer	Open-market sale	Common Stock	16,746^{footnote F1,F2}	$42.70	$715K
Footnote F1 (shares): Represents the number of shares required to be sold by the reporting person to cover the tax withholding obligation in connection with the vesting of restricted stock units subject to performance- and time-based vesting conditions ("PSUs"). This sale is mandated by the Issuer's… Full note on SEC EDGAR Footnote F2 (shares): (continued) The shares vested pursuant to awards that were granted on April 27, 2025. 50,000 shares subject to this PSU vested on January 12, 2026, with an additional 50,000 shares scheduled to vest on April 27, 2027 and the remaining shares vesting in tranches of a combination… Full note on SEC EDGAR
Jan 13, 2026	Akshay Vaishnaw - Officer	Open-market sale	Common Stock	20,438^{footnote F1,F2}	$42.70	$873K
Footnote F1 (shares): Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the vesting of restricted stock units subject to performance-and time-based vesting conditions ("PSUs"). The sale is mandated by the Issuer's… Full note on SEC EDGAR Footnote F2 (shares): (continued) The shares vested pursuant to awards that were granted on April 27, 2025. 50,000 shares subject to this PSU vested on January 12, 2026, with an additional 50,000 shares scheduled to vest on April 27, 2027 and the remaining shares vesting in tranches of a combination… Full note on SEC EDGAR
Jan 13, 2026	David Hallal - Officer	Open-market sale	Common Stock	57,450^{footnote F1,F2}	$42.70	$2.45M
Footnote F1 (shares): Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the vesting of restricted stock units subject to performance-and time-based vesting conditions ("PSUs"). The sale is mandated by the Issuer's… Full note on SEC EDGAR Footnote F2 (shares): (continued) The shares vested pursuant to awards that were granted on April 27, 2025. 125,000 shares subject to this PSU vested on January 12, 2026, with an additional 125,000 shares scheduled to vest on April 27, 2027 and the remaining shares vesting in tranches of a… Full note on SEC EDGAR
Oct 7, 2025	Srinivas Akkaraju	Open-market purchase	Common Stock	12,796	$39.31^{footnote F1}	$503K
Oct 7, 2025	Srinivas Akkaraju	Open-market purchase	Common Stock	12,400	$40.18^{footnote F3}	$498K
Oct 7, 2025	Srinivas Akkaraju	Open-market purchase	Common Stock	4,403	$40.97^{footnote F4}	$180K
Dec 12, 2025	Srinivas Akkaraju	Other	Common Stock	1,064,804	$7.35	$7.83M
Dec 12, 2025	Srinivas Akkaraju	Other	Warrants to Purchase Common Stock	1,064,804	$0.00	-
Footnote F1 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $38.85 to $39.849 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR Footnote F3 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $39.8512 to $40.85 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR Footnote F4 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $40.87 to $41.00 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR
Dec 4, 2025	Mo Qatanani - Officer	Option exercise	Common Stock	65,625^{footnote F1}	$26.05	$1.71M
Dec 4, 2025	Mo Qatanani - Officer	Option exercise	Common Stock	21,093^{footnote F1}	$18.08	$381K
Dec 4, 2025	Mo Qatanani - Officer	Option exercise	Common Stock	5,607^{footnote F1}	$4.86	$27K
Dec 4, 2025	Mo Qatanani - Officer	Option exercise	Common Stock	1,281^{footnote F1}	$7.62	$10K
Dec 4, 2025	Mo Qatanani - Officer	Option exercise	Common Stock	11,250^{footnote F1}	$10.00	$113K
Dec 4, 2025	Mo Qatanani - Officer	Option exercise	Common Stock	23,571^{footnote F1}	$15.75	$371K
Dec 4, 2025	Mo Qatanani - Officer	Option exercise	Common Stock	8,035^{footnote F1}	$35.15	$282K
Dec 4, 2025	Mo Qatanani - Officer	Open-market sale	Common Stock	136,462^{footnote F1}	$45.21^{footnote F9}	$6.17M
Dec 4, 2025	Mo Qatanani - Officer	Option exercise	Stock Option (Right to Buy)	65,625	$0.00	-
Dec 4, 2025	Mo Qatanani - Officer	Option exercise	Stock Option (Right to Buy)	21,093	$0.00	-
Dec 4, 2025	Mo Qatanani - Officer	Option exercise	Stock Option (Right to Buy)	5,607	$0.00	-
Dec 4, 2025	Mo Qatanani - Officer	Option exercise	Stock Option (Right to Buy)	1,281	$0.00	-
Dec 4, 2025	Mo Qatanani - Officer	Option exercise	Stock Option (Right to Buy)	11,250	$0.00	-
Dec 4, 2025	Mo Qatanani - Officer	Option exercise	Stock Option (Right to Buy)	23,571	$0.00	-
Dec 4, 2025	Mo Qatanani - Officer	Option exercise	Stock Option (Right to Buy)	8,035	$0.00	-
Footnote F1 (shares): This transaction was effected by the Reporting Person pursuant to a Rule 10b5-1 trading plan adopted on March 31, 2025. Footnote F9 (price): The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $45.00 to $45.46, inclusive. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon… Full note on SEC EDGAR
Oct 3, 2025	Srinivas Akkaraju	Open-market purchase	Common Stock	11,011	$35.61^{footnote F1}	$392K
Oct 3, 2025	Srinivas Akkaraju	Open-market purchase	Common Stock	56,703	$36.74^{footnote F3}	$2.08M
Oct 3, 2025	Srinivas Akkaraju	Open-market purchase	Common Stock	319,700	$37.42^{footnote F4}	$11.96M
Oct 6, 2025	Srinivas Akkaraju	Open-market purchase	Common Stock	18,414	$37.89^{footnote F5}	$698K
Oct 6, 2025	Srinivas Akkaraju	Open-market purchase	Common Stock	80,863	$38.68^{footnote F6}	$3.13M
Oct 6, 2025	Srinivas Akkaraju	Open-market purchase	Common Stock	13,748	$39.52^{footnote F7}	$543K
Footnote F1 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $35.14 to $36.13 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR Footnote F3 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $36.14 to $37.1391 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR Footnote F4 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $37.14 to $37.6227 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR Footnote F5 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $37.23 to $38.2276 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR Footnote F6 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $38.23 to $39.2298 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR Footnote F7 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $39.23 to $39.84 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR
Oct 8, 2025	David Hallal - Officer	Gift	Common Stock	205,000	$0.00	-
Sep 22, 2025	Mo Qatanani - Officer	Open-market sale	Common Stock	3,353	$30.67	$103K
Sep 16, 2025	Mo Qatanani - Officer	Open-market sale	Common Stock	3,178	$33.52	$107K
Sep 16, 2025	Katie Peng	Open-market sale	Common Stock	930	$32.48	$30K
Sep 16, 2025	Katie Peng	Open-market sale	Common Stock	76	$33.20	$3K
Aug 18, 2025	Caryn Parlavecchio - Officer	Open-market sale	Common Stock	2,178	$31.17	$68K
Jul 16, 2025	Jeffrey S. Flier	Open-market sale	Common Stock	11,136	$40.02	$446K
Jul 8, 2025	Mo Qatanani - Officer	Open-market sale	Common Stock	24,066	$34.44	$829K
May 29, 2025	Michael Gilman	Open-market sale	Common Stock	630	$29.22	$18K
May 29, 2025	Michael Gilman	Open-market sale	Common Stock	2,745	$29.83	$82K
May 22, 2025	Michael Gilman - Director	Grant or award	Common Stock	7,632	$0.00	-
May 22, 2025	Michael Gilman - Director	Grant or award	Stock Option (Right to Buy)	9,206	$0.00	-
May 22, 2025	Srinivas Akkaraju - Director	Grant or award	Common Stock	7,632	$0.00	-
May 22, 2025	Srinivas Akkaraju - Director	Grant or award	Stock Option (Right to Buy)	9,206	$0.00	-
Dec 10, 2024	Invus Public Equities, L.P.	Open-market sale	Common Stock	1,600,000	$41.65	$66.64M
Nov 25, 2024	Invus Public Equities, L.P.	Open-market sale	Common Stock	208,272	$37.63	$7.84M
Nov 25, 2024	Invus Public Equities, L.P.	Open-market sale	Common Stock	43,887	$38.43	$1.69M
Nov 25, 2024	Invus Public Equities, L.P.	Open-market sale	Common Stock	126,442	$39.51	$5.00M
Nov 25, 2024	Invus Public Equities, L.P.	Open-market sale	Common Stock	30,683	$40.14	$1.23M
Nov 25, 2024	Invus Public Equities, L.P.	Open-market sale	Common Stock	149	$40.98	$6K
Nov 22, 2024	Jing L. Marantz - Officer	Option exercise	Common Stock	2,145	$8.59	$18K
Nov 22, 2024	Jing L. Marantz - Officer	Open-market sale	Common Stock	2,145	$30.01	$64K
Nov 25, 2024	Jing L. Marantz - Officer	Option exercise	Common Stock	6,375	$8.59	$55K
Nov 25, 2024	Jing L. Marantz - Officer	Open-market sale	Common Stock	1,000	$38.04	$38K
Nov 25, 2024	Jing L. Marantz - Officer	Open-market sale	Common Stock	2,100	$39.25	$82K
Nov 25, 2024	Jing L. Marantz - Officer	Open-market sale	Common Stock	3,075	$39.93	$123K
Nov 25, 2024	Jing L. Marantz - Officer	Open-market sale	Common Stock	200	$40.72	$8K
Nov 22, 2024	Jing L. Marantz - Officer	Option exercise	Stock Option (Right to Buy)	2,145	$0.00	-
Nov 25, 2024	Jing L. Marantz - Officer	Option exercise	Stock Option (Right to Buy)	6,375	$0.00	-
Nov 11, 2024	Jing L. Marantz - Officer	Option exercise	Common Stock	2,105	$8.59	$18K
Nov 11, 2024	Jing L. Marantz - Officer	Open-market sale	Common Stock	2,105	$30.00	$63K
Nov 11, 2024	Jing L. Marantz - Officer	Option exercise	Stock Option (Right to Buy)	2,105	$0.00	-

Recent SRRK Form 8-K filings

Read SRRK company news

Sep 15, 2026Item 7.01

Read the filing on SEC EDGAR

Sep 14, 2026Item 7.01, 8.01, 9.01

Read the filing on SEC EDGAR

Aug 6, 2026Item 8.01, 9.01

Read the filing on SEC EDGAR

Aug 6, 2026Item 2.02

Recent SRRK Form 144 notices of proposed sale

An insider files Form 144 before selling restricted or control stock. It announces a planned sale. If the sale goes ahead, it shows up later on a Form 4.

Filed	Filer	Relationship	Shares	Market value	Notice
Oct 1, 2026	Katie Peng	Director	1,006	$49K	View on EDGAR
Jul 6, 2026	-	-	-

SRRK insider trading FAQ

What is the latest insider trade for SRRK?

Scholar Rock Holding Corp (SRRK) had 3 insider filings in the last 90 days, with the most recent on 27 October 2026. The full record for SRRK runs to 67 Form 4 filings, the earliest from 7 October 2024. InsiderAlpha adds new Form 4, Form 144 and 8-K filings as they arrive from SEC EDGAR.

How many insiders are buying SRRK stock?

6 insider purchases of SRRK were filed in the last 90 days, totaling $12.00M.

How many insiders are selling SRRK stock?

No insider sales of SRRK were filed in the last 90 days. 70 sales are on record for this company.

Where can I see SRRK SEC filings (Form 4, 10-K, 10-Q, 8-K)?

This page collects SRRK Form 4 insider transactions, Form 144 sale notices and 8-K filings in one place. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.

More Health Care companies with insider activity

Recent insider filings

The EDGAR links open each original Form 4, so you can check any number on this page against the filing it came from.

Oct 27, 2026 - Srinivas Akkaraju view on EDGAR
Sep 25, 2026 - Keith Woods view on EDGAR
Sep 23, 2026 - David Hallal view on EDGAR
Jul 6, 2026 - Jeffrey S. Flier view on EDGAR
Jul 6, 2026 - Michael Gilman view on EDGAR
Jul 6, 2026 - Kristina Burow view on EDGAR
Jul 6, 2026 - Joshua Reed view on EDGAR
Jul 6, 2026 - Katie Peng view on EDGAR
Jun 8, 2026 - Jeffrey S. Flier view on EDGAR

Related companies with recent insider activity

Learn more

How to read insider buying signals: What an open-market purchase by an insider can and cannot tell you.
Form 144 vs Form 4: A Form 144 announces a planned sale; the Form 4 reports it after it happens.
Insider activity in Health Care: Where SRRK's peers are being bought and sold.
Every recent Form 4: The market-wide feed, updated as filings arrive from SEC EDGAR.

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Form 4 transaction type

Transactions

Total value

Open-market purchase

289,470

$12.00M

Bona-fide gift

84,686

Traded

Insider

Transaction

Security

Price

Value

Feb 9, 2026

David Hallal - Officer

Grant or award

Common Stock

128,004^{footnote F1}

$0.00

Footnote F1 (shares): Represents restricted stock units ("RSUs") subject to time-based vesting conditions. Each RSU represents the contingent right to receive, upon vesting of the RSU, one share of the Issuer's common stock. The shares subject to this RSU vest in four annual installments over four… Full note on SEC EDGAR

Feb 9, 2026

Keith Woods - Officer

Grant or award

Common Stock

47,021^{footnote F1}

$0.00

Footnote F1 (shares): Represents restricted stock units ("RSUs") subject to time-based vesting conditions. Each RSU represents the contingent right to receive, upon vesting of the RSU, one share of the Issuer's common stock. The shares subject to this RSU vest in four annual installments over four… Full note on SEC EDGAR

Dec 11, 2025

Invus Global Management, LLC

Other

Common Stock

1,575,008

$7.35

$11.58M

Dec 11, 2025

Invus Global Management, LLC

Other

Warrant (right to buy)

1,575,008

$0.00

Jan 22, 2026

Mo Qatanani - Officer

Open-market sale

Common Stock

2,119^{footnote F1}

$45.87^{footnote F2}

$97K

Jan 22, 2026

Mo Qatanani - Officer

Open-market sale

Common Stock

12,779^{footnote F1}

$46.85^{footnote F4}

$599K

Footnote F1 (shares): This transaction was effected by the Reporting Person pursuant to a Rule 10b5-1 trading plan adopted on March 31, 2025.
Footnote F2 (price): The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $45.43 to $46.42, inclusive. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon… Full note on SEC EDGAR
Footnote F4 (price): The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $46.43 to $47.31, inclusive. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon… Full note on SEC EDGAR

Jan 16, 2026

Mo Qatanani - Officer

Open-market sale

Common Stock

8,406^{footnote F1}

$44.48

$374K

Footnote F1 (shares): Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the vesting of restricted stock units ("RSU") on January 15, 2026. This sale is mandated by the Issuer's election under its equity incentive… Full note on SEC EDGAR

Jan 16, 2026

Caryn Parlavecchio - Officer

Open-market sale

Common Stock

6,600^{footnote F1}

$44.48

$294K

Footnote F1 (shares): Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the vesting of restricted stock units ("RSU") on January 15, 2026. This sale is mandated by the Issuer's election under its equity incentive… Full note on SEC EDGAR

Jan 16, 2026

Jing L. Marantz - Officer

Open-market sale

Common Stock

5,798^{footnote F1}

$44.48

$258K

Footnote F1 (shares): Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the vesting of restricted stock units ("RSU") on January 15, 2026. This sale is mandated by the Issuer's election under its equity incentive… Full note on SEC EDGAR

Jan 16, 2026

Junlin Ho - Officer

Open-market sale

Common Stock

8,016^{footnote F1}

$44.48

$357K

Footnote F1 (shares): Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the vesting of restricted stock units ("RSU") on January 15, 2026. This sale is mandated by the Issuer's election under its equity incentive… Full note on SEC EDGAR

Jan 14, 2026

Mo Qatanani - Officer

Option exercise

Common Stock

1,407^{footnote F1}

$18.08

$25K

Jan 14, 2026

Mo Qatanani - Officer

Option exercise

Common Stock

321^{footnote F1}

$7.62

$2K

Jan 14, 2026

Mo Qatanani - Officer

Option exercise

Common Stock

2,813^{footnote F1}

$10.00

$28K

Jan 14, 2026

Mo Qatanani - Officer

Option exercise

Common Stock

5,893^{footnote F1}

$15.75

$93K

Jan 14, 2026

Mo Qatanani - Officer

Option exercise

Common Stock

2,678^{footnote F1}

$35.15

$94K

Jan 14, 2026

Mo Qatanani - Officer

Open-market sale

Common Stock

13,112^{footnote F1}

$45.20^{footnote F7}

$593K

Jan 14, 2026

Mo Qatanani - Officer

Option exercise

Stock Option (Right to Buy)

1,407

$0.00

Jan 14, 2026

Mo Qatanani - Officer

Option exercise

Stock Option (Right to Buy)

321

$0.00

Jan 14, 2026

Mo Qatanani - Officer

Option exercise

Stock Option (Right to Buy)

2,813

$0.00

Jan 14, 2026

Mo Qatanani - Officer

Option exercise

Stock Option (Right to Buy)

5,893

$0.00

Jan 14, 2026

Mo Qatanani - Officer

Option exercise

Stock Option (Right to Buy)

2,678

$0.00

Footnote F1 (shares): This transaction was effected by the Reporting Person pursuant to a Rule 10b5-1 trading plan adopted on March 31, 2025.
Footnote F7 (price): The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $45.00 to $45.45, inclusive. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon… Full note on SEC EDGAR

Jan 13, 2026

Vikas Sinha - Officer

Open-market sale

Common Stock

16,755^{footnote F1,F2}

$42.70

$715K

Footnote F1 (shares): Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the vesting of restricted stock units subject to performance-and time-based vesting conditions ("PSUs"). The sale is mandated by the Issuer's… Full note on SEC EDGAR
Footnote F2 (shares): (continued) The shares vested pursuant to awards that were granted on April 27, 2025. 50,000 shares subject to this PSU vested on January 12, 2026, with an additional 50,000 shares scheduled to vest on April 27, 2027 and the remaining shares vesting in tranches of a combination… Full note on SEC EDGAR

Jan 13, 2026

Keith Woods - Officer

Open-market sale

Common Stock

16,746^{footnote F1,F2}

$42.70

$715K

Footnote F1 (shares): Represents the number of shares required to be sold by the reporting person to cover the tax withholding obligation in connection with the vesting of restricted stock units subject to performance- and time-based vesting conditions ("PSUs"). This sale is mandated by the Issuer's… Full note on SEC EDGAR
Footnote F2 (shares): (continued) The shares vested pursuant to awards that were granted on April 27, 2025. 50,000 shares subject to this PSU vested on January 12, 2026, with an additional 50,000 shares scheduled to vest on April 27, 2027 and the remaining shares vesting in tranches of a combination… Full note on SEC EDGAR

Jan 13, 2026

Akshay Vaishnaw - Officer

Open-market sale

Common Stock

20,438^{footnote F1,F2}

$42.70

$873K

Footnote F1 (shares): Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the vesting of restricted stock units subject to performance-and time-based vesting conditions ("PSUs"). The sale is mandated by the Issuer's… Full note on SEC EDGAR
Footnote F2 (shares): (continued) The shares vested pursuant to awards that were granted on April 27, 2025. 50,000 shares subject to this PSU vested on January 12, 2026, with an additional 50,000 shares scheduled to vest on April 27, 2027 and the remaining shares vesting in tranches of a combination… Full note on SEC EDGAR

Jan 13, 2026

David Hallal - Officer

Open-market sale

Common Stock

57,450^{footnote F1,F2}

$42.70

$2.45M

Footnote F1 (shares): Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the vesting of restricted stock units subject to performance-and time-based vesting conditions ("PSUs"). The sale is mandated by the Issuer's… Full note on SEC EDGAR
Footnote F2 (shares): (continued) The shares vested pursuant to awards that were granted on April 27, 2025. 125,000 shares subject to this PSU vested on January 12, 2026, with an additional 125,000 shares scheduled to vest on April 27, 2027 and the remaining shares vesting in tranches of a… Full note on SEC EDGAR

Oct 7, 2025

Srinivas Akkaraju

Open-market purchase

Common Stock

12,796

$39.31^{footnote F1}

$503K

Oct 7, 2025

Srinivas Akkaraju

Open-market purchase

Common Stock

12,400

$40.18^{footnote F3}

$498K

Oct 7, 2025

Srinivas Akkaraju

Open-market purchase

Common Stock

4,403

$40.97^{footnote F4}

$180K

Dec 12, 2025

Srinivas Akkaraju

Other

Common Stock

1,064,804

$7.35

$7.83M

Dec 12, 2025

Srinivas Akkaraju

Other

Warrants to Purchase Common Stock

1,064,804

$0.00

Footnote F1 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $38.85 to $39.849 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR
Footnote F3 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $39.8512 to $40.85 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR
Footnote F4 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $40.87 to $41.00 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR

Dec 4, 2025

Mo Qatanani - Officer

Option exercise

Common Stock

65,625^{footnote F1}

$26.05

$1.71M

Dec 4, 2025

Mo Qatanani - Officer

Option exercise

Common Stock

21,093^{footnote F1}

$18.08

$381K

Dec 4, 2025

Mo Qatanani - Officer

Option exercise

Common Stock

5,607^{footnote F1}

$4.86

$27K

Dec 4, 2025

Mo Qatanani - Officer

Option exercise

Common Stock

1,281^{footnote F1}

$7.62

$10K

Dec 4, 2025

Mo Qatanani - Officer

Option exercise

Common Stock

11,250^{footnote F1}

$10.00

$113K

Dec 4, 2025

Mo Qatanani - Officer

Option exercise

Common Stock

23,571^{footnote F1}

$15.75

$371K

Dec 4, 2025

Mo Qatanani - Officer

Option exercise

Common Stock

8,035^{footnote F1}

$35.15

$282K

Dec 4, 2025

Mo Qatanani - Officer

Open-market sale

Common Stock

136,462^{footnote F1}

$45.21^{footnote F9}

$6.17M

Dec 4, 2025

Mo Qatanani - Officer

Option exercise

Stock Option (Right to Buy)

65,625

$0.00

Dec 4, 2025

Mo Qatanani - Officer

Option exercise

Stock Option (Right to Buy)

21,093

$0.00

Dec 4, 2025

Mo Qatanani - Officer

Option exercise

Stock Option (Right to Buy)

5,607

$0.00

Dec 4, 2025

Mo Qatanani - Officer

Option exercise

Stock Option (Right to Buy)

1,281

$0.00

Dec 4, 2025

Mo Qatanani - Officer

Option exercise

Stock Option (Right to Buy)

11,250

$0.00

Dec 4, 2025

Mo Qatanani - Officer

Option exercise

Stock Option (Right to Buy)

23,571

$0.00

Dec 4, 2025

Mo Qatanani - Officer

Option exercise

Stock Option (Right to Buy)

8,035

$0.00

Footnote F1 (shares): This transaction was effected by the Reporting Person pursuant to a Rule 10b5-1 trading plan adopted on March 31, 2025.
Footnote F9 (price): The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $45.00 to $45.46, inclusive. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon… Full note on SEC EDGAR

Oct 3, 2025

Srinivas Akkaraju

Open-market purchase

Common Stock

11,011

$35.61^{footnote F1}

$392K

Oct 3, 2025

Srinivas Akkaraju

Open-market purchase

Common Stock

56,703

$36.74^{footnote F3}

$2.08M

Oct 3, 2025

Srinivas Akkaraju

Open-market purchase

Common Stock

319,700

$37.42^{footnote F4}

$11.96M

Oct 6, 2025

Srinivas Akkaraju

Open-market purchase

Common Stock

18,414

$37.89^{footnote F5}

$698K

Oct 6, 2025

Srinivas Akkaraju

Open-market purchase

Common Stock

80,863

$38.68^{footnote F6}

$3.13M

Oct 6, 2025

Srinivas Akkaraju

Open-market purchase

Common Stock

13,748

$39.52^{footnote F7}

$543K

Footnote F1 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $35.14 to $36.13 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR
Footnote F3 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $36.14 to $37.1391 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR
Footnote F4 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $37.14 to $37.6227 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR
Footnote F5 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $37.23 to $38.2276 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR
Footnote F6 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $38.23 to $39.2298 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR
Footnote F7 (price): The price reported in Column 4 is a weighted average price. These securities were purchased in multiple transactions at prices ranging from $39.23 to $39.84 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of… Full note on SEC EDGAR

Oct 8, 2025

David Hallal - Officer

Gift

Common Stock

205,000

$0.00

Sep 22, 2025

Mo Qatanani - Officer

Open-market sale

Common Stock

3,353

$30.67

$103K

Sep 16, 2025

Mo Qatanani - Officer

Open-market sale

Common Stock

3,178

$33.52

$107K

Sep 16, 2025

Katie Peng

Open-market sale

Common Stock

930

$32.48

$30K

Sep 16, 2025

Katie Peng

Open-market sale

Common Stock

$33.20

$3K

Aug 18, 2025

Caryn Parlavecchio - Officer

Open-market sale

Common Stock

2,178

$31.17

$68K

Jul 16, 2025

Jeffrey S. Flier

Open-market sale

Common Stock

11,136

$40.02

$446K

Jul 8, 2025

Mo Qatanani - Officer

Open-market sale

Common Stock

24,066

$34.44

$829K

May 29, 2025

Michael Gilman

Open-market sale

Common Stock

630

$29.22

$18K

May 29, 2025

Michael Gilman

Open-market sale

Common Stock

2,745

$29.83

$82K

May 22, 2025

Michael Gilman - Director

Grant or award

Common Stock

7,632

$0.00

May 22, 2025

Michael Gilman - Director

Grant or award

Stock Option (Right to Buy)

9,206

$0.00

May 22, 2025

Srinivas Akkaraju - Director

Grant or award

Common Stock

7,632

$0.00

May 22, 2025

Srinivas Akkaraju - Director

Grant or award

Stock Option (Right to Buy)

9,206

$0.00

Dec 10, 2024

Invus Public Equities, L.P.

Open-market sale

Common Stock

1,600,000

$41.65

$66.64M

Nov 25, 2024

Invus Public Equities, L.P.

Open-market sale

Common Stock

208,272

$37.63

$7.84M

Nov 25, 2024

Invus Public Equities, L.P.

Open-market sale

Common Stock

43,887

$38.43

$1.69M

Nov 25, 2024

Invus Public Equities, L.P.

Open-market sale

Common Stock

126,442

$39.51

$5.00M

Nov 25, 2024

Invus Public Equities, L.P.

Open-market sale

Common Stock

30,683

$40.14

$1.23M

Nov 25, 2024

Invus Public Equities, L.P.

Open-market sale

Common Stock

149

$40.98

$6K

Nov 22, 2024

Jing L. Marantz - Officer

Option exercise

Common Stock

2,145

$8.59

$18K

Nov 22, 2024

Jing L. Marantz - Officer

Open-market sale

Common Stock

2,145

$30.01

$64K

Nov 25, 2024

Jing L. Marantz - Officer

Option exercise

Common Stock

6,375

$8.59

$55K

Nov 25, 2024

Jing L. Marantz - Officer

Open-market sale

Common Stock

1,000

$38.04

$38K

Nov 25, 2024

Jing L. Marantz - Officer

Open-market sale

Common Stock

2,100

$39.25

$82K

Nov 25, 2024

Jing L. Marantz - Officer

Open-market sale

Common Stock

3,075

$39.93

$123K

Nov 25, 2024

Jing L. Marantz - Officer

Open-market sale

Common Stock

200

$40.72

$8K

Nov 22, 2024

Jing L. Marantz - Officer

Option exercise

Stock Option (Right to Buy)

2,145

$0.00

Nov 25, 2024

Jing L. Marantz - Officer

Option exercise

Stock Option (Right to Buy)

6,375

$0.00

Nov 11, 2024

Jing L. Marantz - Officer

Option exercise

Common Stock

2,105

$8.59

$18K

Nov 11, 2024

Jing L. Marantz - Officer

Open-market sale

Common Stock

2,105

$30.00

$63K

Nov 11, 2024

Jing L. Marantz - Officer

Option exercise

Stock Option (Right to Buy)

2,105

$0.00

Filed

Filer

Relationship

Market value

Notice

Oct 1, 2026

Katie Peng

Director

1,006

$49K

View on EDGAR

Jul 6, 2026