SPRUCE BIOSCIENCES, INC. (SPRB)
$60.78-$2.52 (-3.98%) Today
Spruce Biosciences Inc is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with unmet medical needs. The company develops biologics and small-molecule product candidates aimed at addressing diseases with unmet medical needs and limited or no approved therapies. Its product candidate, TA-ERT for the treatment of Mucopolysaccharidosis Type IIIB (MPS IIIB), is a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase (rhNAGLU) intended as an enzyme replacement therapy for patients who lack rhNAGLU enzyme activity. TA-ERT is designed to restore rhNAGLU enzyme activity in the central nervous system following intracerebroventricular injection and promote clearance of heparan sulfate in the brain.
https://www.sprucebiosciences.comSEC filings for SPRB on EDGAR
| Form 4 transaction type | Transactions | Shares | Total value |
|---|---|---|---|
| Grant or award | 2 | 13,266 |
Dollar totals are shown for open-market purchases and sales only. Grants, option exercises, gifts and tax withholding are reported by share count because they are not trades at a market price.
21 Form 4 filings on record, the earliest from Dec 20, 2024, newest first.
| Date | Insider | Transaction | Security | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Adrian W. Quartel - Officer | Grant or award | Restricted Stock Units | 13,000 | $0.00 | - | |
| Javier B. Szwarcberg - Officer | Grant or award | Common Stock | 266 | $4.53 | $1K | |
| Daniel K. Spiegelman | Grant or award | Stock Option (Right to Buy) | 1,700 | $0.00 | - | |
| Camilla V. Simpson | Grant or award | Stock Option (Right to Buy) | 1,700 | $0.00 | - | |
| Michael G. Grey - Officer | Grant or award | Stock Option (Right to Buy) | 1,700 | $0.00 | - | |
| Percival Barretto-Ko | Grant or award | Stock Option (Right to Buy) | 1,700 | $0.00 | - | |
 Keli Walbert | Grant or award | Stock Option (Right to Buy) | 1,700 | $0.00 | - | |
 Corwin Dale Hooks - Officer | Grant or award | Restricted Stock Units | 11,000 | $0.00 | - | |
| Javier B. Szwarcberg - Officer | Option exercise | Common Stock | 4,784 | $0.00 | - | |
| Javier B. Szwarcberg - Officer | Tax withholding / forfeiture | Common Stock | 1,539 | $148.16 | $228K | |
| Javier B. Szwarcberg - Officer | Grant or award | Restricted Stock Units | 4,784 | $0.00 | - | |
| Javier B. Szwarcberg - Officer | Option exercise | Restricted Stock Units | 4,784 | $0.00 | - | |
| Samir M. Gharib - Officer | Option exercise | Common Stock | 2,053 | $0.00 | - | |
| Samir M. Gharib - Officer | Tax withholding / forfeiture | Common Stock | 661 | $148.16 | $98K | |
| Samir M. Gharib - Officer | Grant or award | Restricted Stock Units | 2,053 | $0.00 | - | |
| Samir M. Gharib - Officer | Option exercise | Restricted Stock Units | 2,053 | $0.00 | - | |
| Parkman Healthcare Partners LLC - 10% Owner | Open-market purchase | Common Stock, $0.001 par value per share | 256 | $17.91 | $5K | |
| Parkman Healthcare Partners LLC - 10% Owner | Open-market sale | Common Stock, $0.001 par value per share | 232 | $19.33 | $4K | |
| Parkman Healthcare Partners LLC - 10% Owner | Open-market sale | Common Stock, $0.001 par value per share | 25 | $17.46 | $436 | |
| Kirk Ways - Officer | Grant or award | Stock Option (Right to Buy) | 30,000 | $0.00 | - | |
| Daniel K. Spiegelman | Grant or award | Stock Option (Right to Buy) | 30,000 | $0.00 | - | |
| Percival Barretto-Ko | Grant or award | Stock Option (Right to Buy) | 30,000 | $0.00 | - | |
| Bali Muralidhar | Grant or award | Stock Option (Right to Buy) | 30,000 | $0.00 | - | |
| Tiba Aynechi | Grant or award | Stock Option (Right to Buy) | 30,000 | $0.00 | - | |
| Michael G. Grey - Officer | Grant or award | Stock Option (Right to Buy) | 30,000 | $0.00 | - | |
| Camilla V. Simpson | Grant or award | Stock Option (Right to Buy) | 30,000 | $0.00 | - | |
| Ralph William Charlton III - Officer | Option exercise | Common Stock | 106,400 | $0.00 | - | |
| Ralph William Charlton III - Officer | Tax withholding / forfeiture | Common Stock | 37,964 | $40.28 | $20K | |
| Ralph William Charlton III - Officer | Option exercise | Common Stock | 26,600 | $0.00 | - | |
| Ralph William Charlton III - Officer | Tax withholding / forfeiture | Common Stock | 9,491 | $29.15 | $4K | |
| Ralph William Charlton III - Officer | Option exercise | Common Stock | 31,750 | $0.00 | - | |
| Ralph William Charlton III - Officer | Tax withholding / forfeiture | Common Stock | 11,329 | $29.15 | $4K | |
| Ralph William Charlton III - Officer | Option exercise | Restricted Stock Units | 106,400 | $0.00 | - | |
| Ralph William Charlton III - Officer | Option exercise | Restricted Stock Units | 26,600 | $0.00 | - | |
| Ralph William Charlton III - Officer | Option exercise | Restricted Stock Units | 31,750 | $0.00 | - | |
| Javier B. Szwarcberg - Officer | Option exercise | Common Stock | 358,800 | $0.00 | - | |
| Javier B. Szwarcberg - Officer | Tax withholding / forfeiture | Common Stock | 128,020 | $40.28 | $69K | |
| Javier B. Szwarcberg - Officer | Option exercise | Common Stock | 89,700 | $0.00 | - | |
| Javier B. Szwarcberg - Officer | Tax withholding / forfeiture | Common Stock | 32,005 | $29.15 | $12K | |
| Javier B. Szwarcberg - Officer | Option exercise | Common Stock | 111,000 | $0.00 | - | |
| Javier B. Szwarcberg - Officer | Tax withholding / forfeiture | Common Stock | 39,605 | $29.15 | $15K | |
| Javier B. Szwarcberg - Officer | Option exercise | Restricted Stock Units | 358,800 | $0.00 | - | |
| Javier B. Szwarcberg - Officer | Option exercise | Restricted Stock Units | 89,700 | $0.00 | - | |
| Javier B. Szwarcberg - Officer | Option exercise | Restricted Stock Units | 111,000 | $0.00 | - | |
| Samir M. Gharib - Officer | Option exercise | Common Stock | 154,000 | $0.00 | - | |
| Samir M. Gharib - Officer | Tax withholding / forfeiture | Common Stock | 54,948 | $40.28 | $30K | |
| Samir M. Gharib - Officer | Option exercise | Common Stock | 38,500 | $0.00 | - | |
| Samir M. Gharib - Officer | Tax withholding / forfeiture | Common Stock | 13,737 | $29.15 | $5K | |
| Samir M. Gharib - Officer | Option exercise | Common Stock | 37,250 | $0.00 | - | |
| Samir M. Gharib - Officer | Tax withholding / forfeiture | Common Stock | 13,291 | $29.15 | $5K | |
| Samir M. Gharib - Officer | Option exercise | Restricted Stock Units | 154,000 | $0.00 | - | |
| Samir M. Gharib - Officer | Option exercise | Restricted Stock Units | 38,500 | $0.00 | - | |
| Samir M. Gharib - Officer | Option exercise | Restricted Stock Units | 37,250 | $0.00 | - |
SPRUCE BIOSCIENCES, INC. (SPRB) had 2 insider filings in the last 90 days, with the most recent on 2026-07-29. The full record for SPRB runs to 21 Form 4 filings, the earliest from 2024-12-20. InsiderAlpha tracks every Form 4, Form 144, and 8-K filing in real time.
No insider purchases of SPRB were filed in the last 90 days. 1 purchase is on record for this company.
No insider sales of SPRB were filed in the last 90 days. 2 sales are on record for this company.
This page tracks SPRB Form 4 insider transactions, Form 144 sale notices, and 8-K material event disclosures in one timeline. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
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Real-time Form 4 alerts, AI-scored daily trade ideas and 10b5-1 plan flags.
