Prime Medicine, Inc. (PRME) Insider Trading & SEC Filings

Updated Jul 16, 2026 · Last SEC filing 2026-06-08

Prime Medicine, Inc. (PRME) has filed 8 SEC Form 4 insider transactions in the last 90 days, with the most recent on 2026-06-08. 3 Form 8-K material event filings were reported by PRME in the last 90 days. InsiderAlpha tracks every PRME SEC filing — Form 4, Form 144, and 8-K — in real time, including Rule 10b5-1 plan detection.

About Prime Medicine, Inc. (PRME)

SEC CIK	0001894562

90-Day SEC Filing Activity

Form 4 filings (90d)	8
Form 8-K filings (90d)	3
Latest Form 4 filing	2026-06-08

Recent PRME Insider Transactions (Form 4)

Date	Insider	Role	Transaction	Shares	Price	Value	Filing
2025-08-01	ARCH Venture Partners X, LLC	10% Owner	P — Open-market purchase	3.03M	$3.30	$10.00M	SEC
2025-08-01	NELSEN ROBERT	Director	P — Open-market purchase	3.03M	$3.30	$10.00M	SEC
2025-08-01	ARCH Venture Partners XII, LLC	10% Owner	P — Open-market purchase	3.03M	$3.30	$10.00M	SEC
2025-08-01	GV 2021 GP, L.L.C.	Insider	P — Open-market purchase	1.50M	$3.30	$4.95M	SEC
2025-06-30	Liu David R.	10% Owner	P — Open-market purchase	21.0K	$2.52	$53K	SEC
2024-10-08	Gottesdiener Keith Michael	See Remarks	G — Bona-fide gift	226.9K	$0.00	—	SEC
2024-10-08	Gottesdiener Keith Michael	See Remarks	G — Bona-fide gift	226.9K	$0.00	—	SEC

All transactions sourced from SEC EDGAR Form 4 filings for Prime Medicine, Inc. (PRME). Updated in real time as new filings are submitted to the SEC.

Most-Active PRME Insiders — Last 90 Days

Insider	Form 4 filings	Total transaction value
NELSEN ROBERT	1	—
Foster-Cheek Kaye I	1	—
Schenkein David P	1	—
Marrazzo Jeffrey D	1	—
Kelly Michael Aaron	1	—

Recent PRME Form 8-K Material Events

2026-07-08 — Item 8.01 [SEC]
2026-06-08 — Item 5.07 [SEC]
2026-05-07 — Item 2.02, 9.01 [SEC]
2026-04-16 — Item 5.02 · Leadership · neutral [SEC]
Prime Medicine appointed Svetlana Makhni as Chief Financial Officer and principal financial officer, effective April 16, 2026. Ms. Makhni brings over 20 years of experience in biotechnology CFO roles and investment banking, most recently serving as CFO of Marengo Therapeutics.
2026-03-03 — Item 2.02, 7.01, 9.01 · Earnings · neutral [SEC]
Prime Medicine, Inc. announced its financial results and business highlights for the year ended December 31, 2025, via press release on March 3, 2026. The company also posted an updated corporate presentation to its investor relations website.

Recent Insider Filings

2026-06-08 — Schenkein David P (Director)
2026-06-08 — Marrazzo Jeffrey D (Director)
2026-06-08 — NELSEN ROBERT (Director)
2026-06-08 — Kelly Michael Aaron (Director)
2026-06-08 — Foster-Cheek Kaye I (Director)

Form 4 Transaction Code Reference

SEC Form 4 transactions are reported with a one-letter code indicating the type of transaction. Common codes you'll see in PRME insider filings:

P	Open-market purchase by the insider
S	Open-market sale by the insider
A	Grant, award, or other acquisition from the issuer
M	Exercise or conversion of derivative security (e.g. options)
F	Payment of exercise price or tax liability via share withholding
G	Bona-fide gift of securities
D	Disposition to the issuer (e.g. share buyback participation)
J	Other acquisition or disposition
X	Exercise of in-the-money or at-the-money derivative security
C	Conversion of derivative security
V	Transaction voluntarily reported earlier than required

PRME Insider Trading — FAQ

What is the latest insider trade for PRME?: Prime Medicine, Inc. (PRME) had 8 insider filings in the last 90 days, with the most recent on 2026-06-08. InsiderAlpha tracks every Form 4, 10-K, 10-Q, and 8-K filing in real time.
How many insiders are buying PRME stock?: 0 insider purchases of PRME were filed in the last 90 days.
How many insiders are selling PRME stock?: 0 insider sales of PRME were filed in the last 90 days.
Where can I see PRME SEC filings (Form 4, 10-K, 10-Q, 8-K)?: InsiderAlpha aggregates every PRME SEC filing — Form 4 insider transactions, 10-K and 10-Q quarterly reports, and 8-K material event disclosures — in one timeline.

Learn More

Open the live PRME dashboard on InsiderAlpha for real-time alerts, charting, and full historical filing search.