Monopar Therapeutics Inc is a clinical-stage biopharmaceutical company developing a treatment for Wilson disease and novel radiopharmaceuticals for oncology. Its Wilson disease product candidate is ALXN1840, a late-stage, investigational once-daily, oral medicine. The group radiopharmaceutical programs consist of Phase 1-stage MNPR-101-Zr for imaging cancers, and Phase 1a-stage MNPR-101-Lu and late preclinical-stage MNPR-101-Ac for the treatment of cancers that express urokinase plasminogen activator receptor (uPAR). It build drug development pipeline through both in-house efforts and licensing of late preclinical- and clinical-stage therapeutics. The Company operates as a single reportable segment, focusing on the development of clinical and preclinical product candidates.
| Form 4 transaction type | Transactions | Shares | Total value |
|---|---|---|---|
| Open-market sale | 19 | 14,465 | $1.61M |
| Grant or award | 1 | 1,284 | |
| Option exercise | 16 | 55,934 | |
| Tax withholding / forfeiture | 3 | 6,900 |
Dollar totals are shown for open-market purchases and sales only. Grants, option exercises, gifts and tax withholding are reported by share count because they are not trades at a market price.
26 Form 4 filings on record, the earliest from Oct 2, 2024, newest first.
| Date | Insider | Transaction | Security | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Option exercise | Common Stock | 2,055 | $30.00 | $62K | ||
| Option exercise | Common Stock | 2,035 | $14.00 | $28K | ||
| Open-market sale | Common Stock | 485 | $108.83 | $53K | ||
| Open-market sale | Common Stock | 615 | $109.56 | $67K | ||
| Open-market sale | Common Stock | 700 | $110.65 | $77K | ||
| Open-market sale | Common Stock | 1,098 | $111.84 | $123K | ||
| Open-market sale | Common Stock | 602 | $112.93 | $68K | ||
| Open-market sale | Common Stock | 590 | $113.84 | $67K | ||
| Option exercise | Stock Option | 2,055 | $0.00 | - | ||
| Option exercise | Stock Option | 2,035 | $0.00 | - | ||
| Raymond Anderson - Director | Option exercise | Common Stock | 1,402 | $30.00 | $42K | |
| Raymond Anderson - Director | Option exercise | Common Stock | 1,740 | $30.00 | $52K | |
| Raymond Anderson - Director | Open-market sale | Common Stock | 694 | $110.04 | $76K | |
| Raymond Anderson - Director | Open-market sale | Common Stock | 646 | $111.07 | $72K | |
| Raymond Anderson - Director | Open-market sale | Common Stock | 1,802 | $113.05 | $204K | |
| Raymond Anderson - Director | Option exercise | Stock Option | 1,402 | $0.00 | - | |
| Raymond Anderson - Director | Option exercise | Stock Option | 1,740 | $0.00 | - | |
| Patrice Rioux | Option exercise | Common Stock | 1,380 | $0.01 | $7 | |
| Patrice Rioux | Open-market sale | Common Stock | 1 | $111.26 | $111 | |
| Patrice Rioux | Option exercise | Stock Option | 1,380 | $0.00 | - | |
| Open-market sale | Common Stock | 485 | $108.83 | $53K | ||
| Open-market sale | Common Stock | 615 | $109.56 | $67K | ||
| Open-market sale | Common Stock | 700 | $110.65 | $77K | ||
| Open-market sale | Common Stock | 1,098 | $111.84 | $123K | ||
| Open-market sale | Common Stock | 602 | $112.93 | $68K | ||
| Open-market sale | Common Stock | 590 | $113.84 | $67K | ||
| Raymond Anderson - Director | Open-market sale | Common Stock | 694 | $110.04 | $76K | |
| Raymond Anderson - Director | Open-market sale | Common Stock | 646 | $110.07 | $71K | |
| Raymond Anderson - Director | Open-market sale | Common Stock | 1,802 | $113.05 | $204K | |
| Quan Anh Vu - Officer | Option exercise | Common Stock | 1,228 | - | - | |
| Quan Anh Vu - Officer | Tax withholding / forfeiture | Common Stock | 507 | $92.59 | $47K | |
| Quan Anh Vu - Officer | Option exercise | Restricted Stock Unit | 1,228 | $0.00 | - | |
| Chandler Robinson - Officer | Option exercise | Common Stock | 12,873 | - | - | |
| Chandler Robinson - Officer | Tax withholding / forfeiture | Common Stock | 4,084 | $92.59 | $378K | |
| Chandler Robinson - Officer | Option exercise | Restricted Stock Unit | 12,873 | $0.00 | - | |
| Andrew Cittadine - Officer | Option exercise | Common Stock | 5,254 | - | - | |
| Andrew Cittadine - Officer | Tax withholding / forfeiture | Common Stock | 2,309 | $92.59 | $214K | |
| Andrew Cittadine - Officer | Option exercise | Restricted Stock Unit | 5,254 | $0.00 | - | |
| Grant or award | Stock Options | 1,284 | $0.00 | - | ||
| Chandler Robinson - Officer | Option exercise | Common Stock | 6,732 | - | - | |
| Chandler Robinson - Officer | Tax withholding / forfeiture | Common Stock | 1,972 | $54.79 | $108K | |
| Chandler Robinson - Officer | Option exercise | Restricted Stock Unit | 6,732 | $0.00 | - | |
| Andrew Cittadine - Officer | Option exercise | Common Stock | 3,514 | - | - | |
| Andrew Cittadine - Officer | Tax withholding / forfeiture | Common Stock | 1,571 | $54.79 | $86K | |
| Andrew Cittadine - Officer | Option exercise | Restricted Stock Unit | 3,514 | $0.00 | - | |
| Susan Rodriguez - Officer | Grant or award | Stock Options | 48,728 | $0.00 | - | |
| Chandler Robinson - Officer | Other | Common Stock | 62,815 | $0.00 | - | |
| Chandler Robinson - Officer | Option exercise | Common Stock | 8,726 | - | - | |
| Chandler Robinson - Officer | Tax withholding / forfeiture | Common Stock | 2,646 | $81.67 | $216K | |
| Chandler Robinson - Officer | Option exercise | Restricted Stock Units | 8,726 | $0.00 | - | |
| Andrew Cittadine - Officer | Option exercise | Common Stock | 4,327 | - | - | |
| Andrew Cittadine - Officer | Tax withholding / forfeiture | Common Stock | 1,896 | $81.67 | $155K | |
| Andrew Cittadine - Officer | Option exercise | Restricted Stock Units | 4,327 | $0.00 | - | |
| Tactic Pharma LLC - 10% Owner | Open-market sale | Common Stock | 550,229 | $63.61 | $35.00M | |
| Christopher M. Starr - Director | Other | Common Stock | 16,800 | $0.01 | $84 | |
| Christopher M. Starr - Director | Open-market sale | Common Stock | 16,800 | $40.00 | $672K | |
| Christopher M. Starr - Director | Other | Stock Options | 16,800 | $0.00 | - | |
| Chandler Robinson - Officer | Other | Common Stock | 16,800 | $0.01 | $84 | |
| Chandler Robinson - Officer | Open-market sale | Common Stock | 16,800 | $40.00 | $672K | |
| Chandler Robinson - Officer | Other | Stock Options | 16,800 | $0.00 | - | |
| Other | Common Stock | 8,904 | $0.01 | $45 | ||
| Open-market sale | Common Stock | 8,904 | $40.00 | $356K | ||
| Other | Stock Options | 4,200 | $0.00 | - | ||
| Other | Stock Options | 4,704 | $0.00 | - | ||
| Chandler Robinson - Officer | Option exercise | Common Stock | 13,344 | - | - | |
| Chandler Robinson - Officer | Tax withholding / forfeiture | Common Stock | 5,865 | $35.78 | $210K | |
| Chandler Robinson - Officer | Option exercise | Restricted Stock Units | 13,344 | $0.00 | - | |
| Andrew Cittadine - Officer | Option exercise | Common Stock | 6,863 | - | - | |
| Andrew Cittadine - Officer | Tax withholding / forfeiture | Common Stock | 2,990 | $35.78 | $107K | |
| Andrew Cittadine - Officer | Option exercise | Restricted Stock Units | 6,863 | $0.00 | - | |
| Tactic Pharma LLC - 10% Owner | Open-market sale | Common Stock | 33,334 | $35.00 | $1.17M | |
| TacticGem LLC - 10% Owner | Other | Common Stock | 1,433,334 | $0.00 | - | |
| Karthik Radhakrishnan - Officer | Open-market purchase | Common Stock | 1,550 | $16.25 | $25K | |
| Chandler Robinson - Officer | Option exercise | Common Stock | 4,895 | - | - | |
| Chandler Robinson - Officer | Tax withholding / forfeiture | Common Stock | 1,918 | $6.74 | $13K | |
| Chandler Robinson - Officer | Option exercise | Restricted Stock Units | 4,895 | $0.00 | - | |
| Andrew Cittadine - Officer | Option exercise | Common Stock | 1,791 | - | - | |
| Andrew Cittadine - Officer | Tax withholding / forfeiture | Common Stock | 535 | $6.74 | $4K | |
| Andrew Cittadine - Officer | Option exercise | Restricted Stock Units | 1,791 | $0.00 | - |
A Form 144 is notice of an INTENDED sale, not a completed one. It often precedes the Form 4 that reports the trade actually happening.
| Filed | Filer | Relationship | Shares | Market value | Notice |
|---|---|---|---|---|---|
| PATRICE RIOUX | Acting Chief Medical Officer | 1 | $111 | View on EDGAR | |
| KIM TSUCHIMOTO | Director | 8,180 | $907K | View on EDGAR | |
| RAYMOND WILLIAM ANDERSON | Director | 6,284 | $700K | View on EDGAR |
Monopar Therapeutics (MNPR) had 9 insider filings in the last 90 days, with the most recent on 2026-08-29. The full record for MNPR runs to 26 Form 4 filings, the earliest from 2024-10-02. InsiderAlpha tracks every Form 4, Form 144, and 8-K filing in real time.
No insider purchases of MNPR were filed in the last 90 days. 1 purchase is on record for this company.
19 insider sales of MNPR were filed in the last 90 days, totaling $1.61M.
This page tracks MNPR Form 4 insider transactions, Form 144 sale notices, and 8-K material event disclosures in one timeline. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
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Every Form 4 below links to the original document on SEC EDGAR, so the numbers on this page can be checked against the filing they came from.
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