MeiraGTx Holdings PLC is a vertically integrated, clinical-stage genetic medicines company focused on developing targeted therapies for diseases with high unmet need, including radiation-induced xerostomia, Parkinson's disease, and AIPL1-associated retinal dystrophy. The company's pipeline is supported by end-to-end in-house manufacturing capabilities, including GMP viral vector production, plasmid manufacturing, and quality control, enabling development from IND to commercial supply. It also utilizes proprietary platforms in viral vector optimization and riboswitch-based gene regulation to enhance efficacy and reduce dosage. The company operates in the United States, the United Kingdom, and the European Union.
| Form 4 transaction type | Transactions | Shares | Total value |
|---|---|---|---|
| Open-market sale | 4 | 145,659 | $1.97M |
| Grant or award | 12 | 2,712,744 | |
| Option exercise | 2 | 150,000 |
Dollar totals are shown for open-market purchases and sales only. Grants, option exercises, gifts and tax withholding are reported by share count because they are not trades at a market price.
48 Form 4 filings on record, the earliest from Jun 12, 2025, newest first. Filing history page 1 of 2.
| Date | Insider | Transaction | Security | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Open-market sale | Ordinary Shares | 62,000 | $13.86 | $859K | ||
| Richard Giroux - Officer | Open-market sale | Ordinary Shares | 56,000 | $12.51 | $701K | |
| Stuart Naylor - Officer | Open-market sale | Ordinary Shares | 2,547 | $13.86 | $35K | |
| Stuart Naylor - Officer | Open-market sale | Ordinary Shares | 25,112 | $14.90 | $374K | |
| Robert K. Zeldin - Officer | Grant or award | Restricted Share Units | 100,000 | $0.00 | - | |
| Robert J. Wollin - Officer | Grant or award | Restricted Share Units | 100,000 | $0.00 | - | |
| Stuart Naylor - Officer | Grant or award | Restricted Share Units | 70,000 | $0.00 | - | |
| Richard Giroux - Officer | Grant or award | Restricted Share Units | 980,000 | $0.00 | - | |
| Grant or award | Restricted Share Units | 980,000 | $0.00 | - | ||
| Debra Yu | Grant or award | Restricted Share Units | 60,000 | $0.00 | - | |
| Thomas E. Shenk | Grant or award | Restricted Share Units | 69,662 | $0.00 | - | |
| Grant or award | Restricted Share Units | 60,000 | $0.00 | - | ||
| Grant or award | Restricted Share Units | 66,641 | $0.00 | - | ||
| Ellen Hukkelhoven | Grant or award | Restricted Share Units | 60,000 | $0.00 | - | |
| Keith R. Harris | Grant or award | Restricted Share Units | 106,441 | $0.00 | - | |
| PERCEPTIVE ADVISORS LLC | Grant or award | Restricted Share Units | 60,000 | $0.00 | - | |
| Keith R. Harris | Option exercise | Ordinary Shares | 75,000 | - | - | |
| Keith R. Harris | Option exercise | Restricted Share Units | 75,000 | $0.00 | - | |
| Richard Giroux - Officer | Gift | Ordinary Shares | 7,000 | $0.00 | - | |
| Open-market sale | Ordinary Shares | 62,000 | $9.17 | $569K | ||
| Penny Renee Fleck - Officer | Grant or award | Stock Option (Right to Buy) | 100,000 | $0.00 | - | |
| Penny Renee Fleck - Officer | Grant or award | Restricted Share Units | 100,000 | $0.00 | - | |
| Robert K. Zeldin - Officer | Tax withholding / forfeiture | Ordinary Shares | 7,814 | $7.73 | $60K | |
| PERCEPTIVE ADVISORS LLC | Grant or award | Ordinary Shares | 555,555 | $9.00 | $5.00M | |
| PERCEPTIVE ADVISORS LLC | Grant or award | Warrant (Right to Buy) | 400,000 | - | - | |
| PERCEPTIVE ADVISORS LLC | Grant or award | Warrant (Right to Buy) | 300,000 | - | - | |
| PERCEPTIVE ADVISORS LLC | Derivative | Warrant (Right to Buy) | 400,000 | - | - | |
| PERCEPTIVE ADVISORS LLC | Derivative | Warrant (Right to Buy) | 300,000 | - | - | |
| PERCEPTIVE ADVISORS LLC | Grant or award | Warrant (Right to Buy) | 400,000 | - | - | |
| PERCEPTIVE ADVISORS LLC | Grant or award | Warrant (Right to Buy) | 300,000 | - | - | |
| Richard Giroux - Officer | Open-market sale | Ordinary Shares | 56,000 | $10.22 | $572K | |
| Stuart Naylor - Officer | Open-market sale | Ordinary Shares | 27,661 | $9.36 | $259K | |
| Open-market sale | Ordinary Shares | 62,000 | $7.41 | $459K | ||
| Robert K. Zeldin - Officer | Option exercise | Ordinary Shares | 7,500 | - | - | |
| Robert K. Zeldin - Officer | Tax withholding / forfeiture | Ordinary Shares | 2,952 | $7.45 | $22K | |
| Robert K. Zeldin - Officer | Option exercise | Restricted Share Units | 7,500 | $0.00 | - | |
| Robert J. Wollin - Officer | Option exercise | Ordinary Shares | 11,250 | - | - | |
| Robert J. Wollin - Officer | Tax withholding / forfeiture | Ordinary Shares | 5,949 | $7.45 | $44K | |
| Robert J. Wollin - Officer | Option exercise | Restricted Share Units | 11,250 | $0.00 | - | |
| Stuart Naylor - Officer | Option exercise | Ordinary Shares | 25,000 | - | - | |
| Stuart Naylor - Officer | Tax withholding / forfeiture | Ordinary Shares | 11,750 | $7.45 | $88K | |
| Stuart Naylor - Officer | Option exercise | Restricted Share Units | 25,000 | $0.00 | - | |
| Richard Giroux - Officer | Option exercise | Ordinary Shares | 60,000 | - | - | |
| Richard Giroux - Officer | Tax withholding / forfeiture | Ordinary Shares | 31,726 | $7.45 | $236K | |
| Richard Giroux - Officer | Option exercise | Restricted Share Units | 60,000 | $0.00 | - | |
| Option exercise | Ordinary Shares | 62,500 | - | - | ||
| Tax withholding / forfeiture | Ordinary Shares | 33,048 | $7.45 | $246K | ||
| Option exercise | Restricted Share Units | 62,500 | $0.00 | - | ||
| Robert K. Zeldin - Officer | Option exercise | Ordinary Shares | 35,000 | - | - | |
| Robert K. Zeldin - Officer | Tax withholding / forfeiture | Ordinary Shares | 13,951 | $7.42 | $104K | |
| Robert K. Zeldin - Officer | Option exercise | Restricted Share Units | 35,000 | $0.00 | - |
A Form 144 is notice of an INTENDED sale, not a completed one. It often precedes the Form 4 that reports the trade actually happening.
| Filed | Filer | Relationship | Shares | Market value | Notice |
|---|---|---|---|---|---|
| Alexandria Forbes | Officer, Director | 62,000 | $859K | View on EDGAR | |
| - | - | - | - | View on EDGAR | |
| - | - | - | - | View on EDGAR |
MeiraGTx Holdings plc (MGTX) had 16 insider filings in the last 90 days, with the most recent on 2026-08-19. The full record for MGTX runs to 48 Form 4 filings, the earliest from 2025-06-12. InsiderAlpha tracks every Form 4, Form 144, and 8-K filing in real time.
No insider purchases of MGTX were filed in the last 90 days.
4 insider sales of MGTX were filed in the last 90 days, totaling $1.97M.
This page tracks MGTX Form 4 insider transactions, Form 144 sale notices, and 8-K material event disclosures in one timeline. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
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Every Form 4 below links to the original document on SEC EDGAR, so the numbers on this page can be checked against the filing they came from.
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