Skip to content
Home / Companies / GPCR GPC
Structure Therapeutics Inc. (GPCR) XNAS PHARMACEUTICAL PREPARATIONS Net insider selling (90d)
Latest GPCR Insider Trades
About Structure Therapeutics Inc. (GPCR) Structure Therapeutics Inc is a clinical-stage biopharmaceutical company developing novel oral small-molecule therapeutics to treat a wide range of chronic diseases with unmet medical needs. Its differentiated technology platform leverages both structure-based drug discovery and expertise in computational chemistry to discover and develop small molecule therapeutics against G-protein coupled receptors (GPCRs). The group operates and manages its business as one reportable and operating segment, which is the business of research and development of medicines that target chronic diseases with unmet medical needs.
Headquarters SOUTH SAN FRANCISCO, CA
Employees 281
Listed 2023
Exchange XNAS https://www.structuretx.com SEC filings for GPCR on EDGAR
90-Day SEC Filing Activity Form 4 transaction type Transactions Shares Total value Open-market sale 10 41,086 $2.07M Grant or award 8 552,096 Option exercise 8 141,804
GPCR Insider Transactions (Form 4) 79 41 Form 4 filings on record, the earliest from Jun 23, 2025, newest first. Filing history page 1 of 2.
Date Insider Transaction Security Shares Price Value Aug 18, 2026 XL Xichen Lin - Officer Option exercise Ordinary Shares 11,817
Recent GPCR Form 8-K Filings 5
Recent GPCR Form 144 Notices of Proposed Sale 1 A Form 144 is notice of an INTENDED sale, not a completed one. It often precedes the Form 4 that reports the trade actually happening.
Filed Filer Relationship Shares Market value Notice Jun 25, 2026 - - - - View on EDGAR
GPCR Insider Trading - FAQ
What is the latest insider trade for GPCR? Structure Therapeutics Inc. (GPCR) had 12 insider filings in the last 90 days, with the most recent on 2026-08-20. The full record for GPCR runs to 41 Form 4 filings, the earliest from 2025-06-23. InsiderAlpha tracks every Form 4, Form 144, and 8-K filing in real time.
How many insiders are buying GPCR stock? No insider purchases of GPCR were filed in the last 90 days.
How many insiders are selling GPCR stock? 10 insider sales of GPCR were filed in the last 90 days, totaling $2.07M.
Where can I see GPCR SEC filings (Form 4, 10-K, 10-Q, 8-K)? This page tracks GPCR Form 4 insider transactions, Form 144 sale notices, and 8-K material event disclosures in one timeline. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
How can I follow GPCR insider buys? Create a free InsiderAlpha account and press Watch on this page to add GPCR to your watchlist. A free account also opens the full scored daily plan with every past day and 3 months of price history. No card is required. Sign up at https://insideralpha.ai/register.
More Health Care Companies with Insider Activity Every Form 4 below links to the original document on SEC EDGAR, so the numbers on this page can be checked against the filing they came from.
Related Companies - Recent Insider Activity What is SEC Form 4? The filing insiders must submit within two business days of a trade, and how to read its transaction codes. Track GPCR insider activity as it files Real-time Form 4 alerts, AI-scored daily trade ideas and 10b5-1 plan flags.
Sign up free - Officer
XL Xichen Lin - Officer Open-market sale $153K
Aug 4, 2026
XL Xichen Lin - Officer Open-market sale $42K
Aug 4, 2026
FMR LLC Open-market sale $68K
Jul 22, 2026
FMR LLC Open-market sale $805K
Jul 22, 2026
XL Xichen Lin - Officer Open-market sale $319K
Jul 14, 2026
Market cap $3.38B
P/E ratio -
Dividend yield -
Average volume 713.4K
52 week high $94.90
52 week low $18.26
Today's high -
Today's low -
Open -
Volume -
Previous close $47.37
Shares outstanding 71.31M Market cap
$3.38B
281 employees
GPCR Insider Sentiment - Last 90 Days Share of open-market insider dollar volume that was buying versus selling, from SEC Form 4 filings.
0% Buying 100% Selling
0 insider purchases totaling $0 against 10 sales totaling $2.07M.
Most-Active GPCR Insiders - Last 90 Days 10 Other acquisition / disposition 8 94,536
Dollar totals are shown for open-market purchases and sales only. Grants, option exercises, gifts and tax withholding are reported by share count because they are not trades at a market price.
Aug 18, 2026 XL Xichen Lin - Officer Other Ordinary Shares 11,817 $0.00 -
Aug 18, 2026 XL Xichen Lin - Officer Option exercise Share Option (right to buy) 11,817 $0.00 -
Aug 18, 2026 XL Xichen Lin - Officer Other American Depositary Shares 3,939 $0.00 -
Aug 18, 2026 XL Xichen Lin - Officer Open-market sale American Depositary Shares 3,020 $53.13 $160K
Aug 18, 2026 XL Xichen Lin - Officer Open-market sale American Depositary Shares 519 $54.20 $28K
Aug 18, 2026 XL Xichen Lin - Officer Open-market sale American Depositary Shares 400 $55.05 $22K
Aug 6, 2026 JB John Joseph Berrios - Officer Grant or award Share option (right to buy) 174,612 $0.00 -
Aug 4, 2026 XL Xichen Lin - Officer Option exercise Ordinary Shares 11,817 $0.34 $4K
Aug 4, 2026 XL Xichen Lin - Officer Other Ordinary Shares 11,817 $0.00 -
Aug 4, 2026 XL Xichen Lin - Officer Option exercise Share Option (right to buy) 11,817 $0.00 -
Aug 4, 2026 XL Xichen Lin - Officer Other American Depositary Shares 3,939 $0.00 -
Aug 4, 2026 XL Xichen Lin - Officer Open-market sale American Depositary Shares 3,100 $49.29 $153K
Aug 4, 2026 XL Xichen Lin - Officer Open-market sale American Depositary Shares 839 $50.03 $42K
Jul 22, 2026 FMR LLC Open-market sale American Depositary Shares 1,367 $50.07 $68K
Jul 22, 2026 FMR LLC Open-market sale American Depositary Shares 16,085 $50.07 $805K
Jul 14, 2026 XL Xichen Lin - Officer Option exercise Ordinary Shares 23,634 $0.34 $8K
Jul 14, 2026 XL Xichen Lin - Officer Other Ordinary Shares 23,634 $0.00 -
Jul 14, 2026 XL Xichen Lin - Officer Option exercise Share Option (right to buy) 23,634 $0.00 -
Jul 14, 2026 XL Xichen Lin - Officer Other American Depositary Shares 7,878 $0.00 -
Jul 14, 2026 XL Xichen Lin - Officer Open-market sale American Depositary Shares 6,278 $50.80 $319K
Jul 14, 2026 XL Xichen Lin - Officer Open-market sale American Depositary Shares 1,600 $51.71 $83K
Jun 25, 2026 XL Xichen Lin - Officer Option exercise Ordinary Shares 23,634 $0.34 $8K
Jun 25, 2026 XL Xichen Lin - Officer Other Ordinary Shares 23,634 $0.00 -
Jun 25, 2026 XL Xichen Lin - Officer Option exercise Share Option (right to buy) 23,634 $0.00 -
Jun 25, 2026 XL Xichen Lin - Officer Other American Depositary Shares 7,878 $0.00 -
Jun 25, 2026 XL Xichen Lin - Officer Open-market sale American Depositary Shares 7,878 $49.08 $387K
Jun 17, 2026 AR Angus C. Russell Grant or award Share Option (right to buy) 39,453 $0.00 -
Jun 17, 2026 TL Ted W. Love Grant or award Share Option (right to buy) 39,453 $0.00 -
Jun 17, 2026 ED Eric Dobmeier Grant or award Share Option (right to buy) 39,453 $0.00 -
Jun 17, 2026 ST Sharon Tetlow Grant or award Share Option (right to buy) 39,453 $0.00 -
Jun 17, 2026 DW Daniel G. Welch Grant or award Share Option (right to buy) 39,453 $0.00 -
Apr 15, 2026 ML Matthew Lang - Officer Grant or award Ordinary Shares 184,614 $0.00 -
Apr 15, 2026 ML Matthew Lang - Officer Grant or award Share option (right to buy) 223,776 $0.00 -
Apr 14, 2026 FMR LLC Open-market sale American Depositary Shares 1,367 $55.07 $75K
Apr 14, 2026 FMR LLC Open-market sale American Depositary Shares 16,085 $55.07 $886K
Mar 19, 2026 AH Ashley Hall - Officer Grant or award Ordinary Shares 47,706 $0.00 -
Mar 19, 2026 AH Ashley Hall - Officer Grant or award Employee Stock Option (right to buy) 59,073 $0.00 -
Mar 19, 2026 CC Crespo Blas Coll - Officer Grant or award Ordinary Shares 75,897 $0.00 -
Mar 19, 2026 CC Crespo Blas Coll - Officer Grant or award Employee Stock Option (right to buy) 93,984 $0.00 -
Mar 19, 2026 YM Yingli Ma - Officer Grant or award Ordinary Shares 32,526 $0.00 -
Mar 19, 2026 YM Yingli Ma - Officer Grant or award Employee Stock Option (right to buy) 40,278 $0.00 -
Mar 19, 2026 XL Xichen Lin - Officer Grant or award Ordinary Shares 43,368 $0.00 -
Mar 19, 2026 XL Xichen Lin - Officer Grant or award Employee Stock Option (right to buy) 53,703 $0.00 -
Mar 19, 2026 JY Jun Yoon - Officer Grant or award Ordinary Shares 104,085 $0.00 -
Mar 19, 2026 JY Jun Yoon - Officer Grant or award Employee Stock Option (right to buy) 128,892 $0.00 -
Mar 19, 2026 RS Raymond C. Stevens - Officer Grant or award Employee Stock Option (right to buy) 322,230 $0.00 -
Mar 3, 2026 CC Crespo Blas Coll - Officer Tax withholding / forfeiture Ordinary Shares 11,826 $20.99 $248K
Mar 3, 2026 YM Yingli Ma - Officer Tax withholding / forfeiture Ordinary Shares 11,313 $20.99 $237K
Mar 3, 2026 XL Xichen Lin - Officer Tax withholding / forfeiture Ordinary Shares 18,735 $20.99 $393K
Mar 3, 2026 JY Jun Yoon - Officer Tax withholding / forfeiture Ordinary Shares 22,305 $20.99 $468K
Mar 3, 2026 AH Ashley Hall - Officer Tax withholding / forfeiture Ordinary Shares 4,836 $20.99 $102K
May 20, 2025 AH Ashley Hall - Officer Grant or award American Depositary Shares 225 $0.00 -
Nov 20, 2025 AH Ashley Hall - Officer Grant or award American Depositary Shares 237 $0.00 -
Nov 20, 2025 RS Raymond C. Stevens - Officer Grant or award American Depositary Shares 824 $0.00 -
Mar 3, 2026 RS Raymond C. Stevens - Officer Tax withholding / forfeiture Ordinary Shares 53,454 $20.99 $1.12M
Jan 15, 2026 FMR LLC Open-market sale American Depositary Shares 465 $82.10 $38K
Jan 15, 2026 FMR LLC Open-market sale American Depositary Shares 330 $83.35 $28K
Jan 15, 2026 FMR LLC Open-market sale American Depositary Shares 552 $84.22 $46K
Jan 15, 2026 FMR LLC Open-market sale American Depositary Shares 20 $85.04 $2K
Jan 15, 2026 FMR LLC Open-market sale American Depositary Shares 5,477 $82.10 $450K
Jan 15, 2026 FMR LLC Open-market sale American Depositary Shares 3,880 $83.35 $323K
Jan 15, 2026 FMR LLC Open-market sale American Depositary Shares 6,498 $84.22 $547K
Jan 15, 2026 FMR LLC Open-market sale American Depositary Shares 230 $85.04 $20K
Dec 8, 2025 FMR LLC Open-market sale American Depositary Shares 709 $92.52 $66K
Dec 8, 2025 FMR LLC Open-market sale American Depositary Shares 183 $94.00 $17K
Dec 8, 2025 FMR LLC Open-market sale American Depositary Shares 475 $94.61 $45K
Dec 8, 2025 FMR LLC Open-market sale American Depositary Shares 1,414 $61.05 $86K
Dec 8, 2025 FMR LLC Open-market sale American Depositary Shares 1,320 $61.45 $81K
Dec 8, 2025 FMR LLC Open-market sale American Depositary Shares 8,337 $92.52 $771K
Dec 8, 2025 FMR LLC Open-market sale American Depositary Shares 2,159 $94.00 $203K
Dec 8, 2025 FMR LLC Open-market sale American Depositary Shares 5,589 $94.61 $529K
Dec 8, 2025 FMR LLC Open-market sale American Depositary Shares 16,635 $61.05 $1.02M
Dec 8, 2025 FMR LLC Open-market sale American Depositary Shares 15,535 $61.45 $955K
Sep 18, 2025 CC Crespo Blas Coll - Officer Tax withholding / forfeiture Ordinary Shares 8,106 $7.74 $63K
Sep 18, 2025 AH Ashley Hall - Officer Tax withholding / forfeiture Ordinary Shares 6,021 $7.74 $47K
$GYRE
GYRE THERAPEUTICS, INC.
$IONS
IONIS PHARMACEUTICALS INC
