Crinetics Pharmaceuticals Inc is a commercial-stage pharmaceutical company focused on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors. Its main product, Palsonify (paltusotine), is a once-daily, oral treatment approved by the FDA for adults with acromegaly who have had an inadequate response to surgery and/or for whom surgery is not an option. Additionally, the company's development pipeline includes several programs, including a late-stage investigational candidate, atumelnant, currently in development for CAH and ADCS, and CRN09682, a NDC candidate that is being developed to treat SST2-expressing NETs and other SST2-expressing solid tumors.
| Form 4 transaction type | Transactions | Shares | Total value |
|---|---|---|---|
| Open-market sale | 3 | 9,900 | $366K |
| Grant or award | 15 | 110,056 | |
| Option exercise | 8 | 39,856 | |
| Bona-fide gift | 14 | 1,937,600 |
Dollar totals are shown for open-market purchases and sales only. Grants, option exercises, gifts and tax withholding are reported by share count because they are not trades at a market price.
37 Form 4 filings on record, the earliest from Oct 7, 2024, newest first. Filing history page 1 of 2.
| Date | Insider | Transaction | Security | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Grant or award | Common Stock | 471 | $0.00 | - | ||
| Richard Scott Struthers - Officer | Option exercise | Common Stock | 3,969 | $25.19 | $100K | |
| Richard Scott Struthers - Officer | Option exercise | Common Stock | 4,422 | $22.61 | $100K | |
| Richard Scott Struthers - Officer | Option exercise | Common Stock | 6,542 | $15.29 | $100K | |
| Richard Scott Struthers - Officer | Option exercise | Common Stock | 4,995 | $20.02 | $100K | |
| Richard Scott Struthers - Officer | Option exercise | Stock Option (Right to Buy) | 3,969 | $0.00 | - | |
| Richard Scott Struthers - Officer | Option exercise | Stock Option (Right to Buy) | 4,422 | $0.00 | - | |
| Richard Scott Struthers - Officer | Option exercise | Stock Option (Right to Buy) | 6,542 | $0.00 | - | |
| Richard Scott Struthers - Officer | Option exercise | Stock Option (Right to Buy) | 4,995 | $0.00 | - | |
| Open-market sale | Common Stock | 3,000 | $40.00 | $120K | ||
| Caren Deardorf - Director | Grant or award | Stock Option (Right to Buy) | 9,730 | $0.00 | - | |
| Caren Deardorf - Director | Grant or award | Common Stock | 5,925 | $0.00 | - | |
| Matthew K. Fust - Director | Grant or award | Stock Option (Right to Buy) | 9,730 | $0.00 | - | |
| Matthew K. Fust - Director | Grant or award | Common Stock | 5,925 | $0.00 | - | |
| Grant or award | Common Stock | 5,925 | $0.00 | - | ||
| Grant or award | Stock Option (Right to Buy) | 9,730 | $0.00 | - | ||
| Grant or award | Stock Option (Right to Buy) | 9,730 | $0.00 | - | ||
| Grant or award | Common Stock | 5,925 | $0.00 | - | ||
| Grant or award | Stock Option (Right to Buy) | 9,730 | $0.00 | - | ||
| Grant or award | Common Stock | 5,925 | $0.00 | - | ||
| Wendell Wierenga - Director | Grant or award | Common Stock | 5,925 | $0.00 | - | |
| Wendell Wierenga - Director | Grant or award | Stock Option (Right to Buy) | 9,730 | $0.00 | - | |
| Stephanie Okey - Director | Grant or award | Stock Option (Right to Buy) | 9,730 | $0.00 | - | |
| Stephanie Okey - Director | Grant or award | Common Stock | 5,925 | $0.00 | - | |
| Stephanie Okey - Director | Open-market sale | Common Stock | 6,292 | $35.62 | $224K | |
| Stephanie Okey - Director | Open-market sale | Common Stock | 608 | $36.22 | $22K | |
| Richard Scott Struthers - Officer | Gift | Common Stock | 111,100 | $0.00 | - | |
| Richard Scott Struthers - Officer | Gift | Common Stock | 222,200 | $0.00 | - | |
| Richard Scott Struthers - Officer | Gift | Common Stock | 222,200 | $0.00 | - | |
| Richard Scott Struthers - Officer | Gift | Common Stock | 222,200 | $0.00 | - | |
| Richard Scott Struthers - Officer | Gift | Common Stock | 222,200 | $0.00 | - | |
| Richard Scott Struthers - Officer | Gift | Common Stock | 80,000 | $0.00 | - | |
| Richard Scott Struthers - Officer | Gift | Common Stock | 80,000 | $0.00 | - | |
| Richard Scott Struthers - Officer | Gift | Common Stock | 111,100 | $0.00 | - | |
| Richard Scott Struthers - Officer | Gift | Common Stock | 111,100 | $0.00 | - | |
| Richard Scott Struthers - Officer | Gift | Common Stock | 111,100 | $0.00 | - | |
| Richard Scott Struthers - Officer | Gift | Common Stock | 111,100 | $0.00 | - | |
| Richard Scott Struthers - Officer | Gift | Common Stock | 111,100 | $0.00 | - | |
| Richard Scott Struthers - Officer | Gift | Common Stock | 111,100 | $0.00 | - | |
| Richard Scott Struthers - Officer | Gift | Common Stock | 111,100 | $0.00 | - | |
| Jeff E. Knight - Officer | Option exercise | Common Stock | 49,474 | $23.98 | $1.19M | |
| Jeff E. Knight - Officer | Option exercise | Common Stock | 9,624 | $20.02 | $193K | |
| Jeff E. Knight - Officer | Option exercise | Common Stock | 19,336 | $19.64 | $380K | |
| Jeff E. Knight - Officer | Open-market sale | Common Stock | 85,163 | $40.10 | $3.42M | |
| Jeff E. Knight - Officer | Option exercise | Stock Option (Right to Buy) | 49,474 | $0.00 | - | |
| Jeff E. Knight - Officer | Option exercise | Stock Option (Right to Buy) | 9,624 | $0.00 | - | |
| Jeff E. Knight - Officer | Option exercise | Stock Option (Right to Buy) | 19,336 | $0.00 | - | |
| Jeff E. Knight - Officer | Open-market sale | Common Stock | 5,950 | $37.11 | $221K | |
| Jeff E. Knight - Officer | Open-market sale | Common Stock | 3,961 | $37.77 | $150K | |
| Stephen F. Betz - Officer | Open-market sale | Common Stock | 6,371 | $37.11 | $236K | |
| Stephen F. Betz - Officer | Open-market sale | Common Stock | 4,241 | $37.77 | $160K | |
| Richard Scott Struthers - Officer | Open-market sale | Common Stock | 13,196 | $37.11 | $490K | |
| Richard Scott Struthers - Officer | Open-market sale | Common Stock | 8,785 | $37.77 | $332K | |
| Open-market sale | Common Stock | 523 | $36.77 | $19K | ||
| Open-market sale | Common Stock | 4,477 | $36.08 | $162K | ||
| Stephanie Okey - Director | Open-market sale | Common Stock | 3,000 | $39.67 | $119K | |
| Open-market sale | Common Stock | 6,713 | $39.67 | $266K | ||
| Richard Scott Struthers - Officer | Grant or award | Common Stock | 62,000 | $0.00 | - | |
| Richard Scott Struthers - Officer | Grant or award | Stock Option (Right to Buy) | 228,000 | $0.00 | - | |
| Grant or award | Common Stock | 32,000 | $0.00 | - | ||
| Grant or award | Stock Option (Right to Buy) | 50,000 | $0.00 | - | ||
| Jeff E. Knight - Officer | Grant or award | Common Stock | 34,000 | $0.00 | - | |
| Jeff E. Knight - Officer | Grant or award | Stock Option (Right to Buy) | 55,000 | $0.00 | - | |
| Stephen F. Betz - Officer | Grant or award | Common Stock | 30,000 | $0.00 | - | |
| Stephen F. Betz - Officer | Grant or award | Stock Option (Right to Buy) | 47,000 | $0.00 | - | |
| Isabel Kalofonos - Officer | Grant or award | Common Stock | 34,000 | $0.00 | - | |
| Isabel Kalofonos - Officer | Grant or award | Stock Option (Right to Buy) | 55,000 | $0.00 | - | |
| Dana Pizzuti - Officer | Option exercise | Common Stock | 5,000 | $16.89 | $84K | |
| Dana Pizzuti - Officer | Open-market sale | Common Stock | 5,000 | $45.02 | $225K | |
| Dana Pizzuti - Officer | Option exercise | Stock Option (Right to Buy) | 5,000 | $0.00 | - | |
| Dana Pizzuti - Officer | Option exercise | Common Stock | 5,000 | $16.89 | $84K | |
| Dana Pizzuti - Officer | Open-market sale | Common Stock | 4,900 | $42.65 | $209K | |
| Dana Pizzuti - Officer | Open-market sale | Common Stock | 100 | $43.27 | $4K | |
| Dana Pizzuti - Officer | Option exercise | Stock Option (Right to Buy) | 5,000 | $0.00 | - | |
| Dana Pizzuti - Officer | Option exercise | Common Stock | 5,000 | $16.89 | $84K | |
| Dana Pizzuti - Officer | Open-market sale | Common Stock | 5,000 | $41.81 | $209K | |
| Dana Pizzuti - Officer | Option exercise | Stock Option (Right to Buy) | 5,000 | $0.00 | - | |
| Richard Scott Struthers - Officer | Open-market sale | Common Stock | 4,000 | $45.00 | $180K | |
| Matthew K. Fust - Director | Option exercise | Common Stock | 10,000 | $1.91 | $19K | |
| Matthew K. Fust - Director | Open-market sale | Common Stock | 16,000 | $44.75 | $716K | |
| Matthew K. Fust - Director | Option exercise | Stock Option (Right to Buy) | 10,000 | $0.00 | - | |
| Dana Pizzuti - Officer | Option exercise | Common Stock | 5,000 | $16.89 | $84K | |
| Dana Pizzuti - Officer | Open-market sale | Common Stock | 5,000 | $32.10 | $161K | |
| Dana Pizzuti - Officer | Option exercise | Stock Option (Right to Buy) | 5,000 | $0.00 | - |
A Form 144 is notice of an INTENDED sale, not a completed one. It often precedes the Form 4 that reports the trade actually happening.
| Filed | Filer | Relationship | Shares | Market value | Notice |
|---|---|---|---|---|---|
| - | - | - | - | View on EDGAR | |
| - | - | - | - | View on EDGAR | |
| - | - | - | - | View on EDGAR |
Crinetics Pharmaceuticals, Inc. (CRNX) had 12 insider filings in the last 90 days, with the most recent on 2026-08-24. The full record for CRNX runs to 37 Form 4 filings, the earliest from 2024-10-07. InsiderAlpha tracks every Form 4, Form 144, and 8-K filing in real time.
No insider purchases of CRNX were filed in the last 90 days.
3 insider sales of CRNX were filed in the last 90 days, totaling $366K.
This page tracks CRNX Form 4 insider transactions, Form 144 sale notices, and 8-K material event disclosures in one timeline. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
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Every Form 4 below links to the original document on SEC EDGAR, so the numbers on this page can be checked against the filing they came from.
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