Aptevo Therapeutics Inc is a clinical-stage research and development biotechnology company focused on developing novel immunotherapeutic candidates for the treatment of different forms of cancer. Its clinical candidates are; ALG.APV-527, which targets co-stimulatory receptors and tumor antigens, and CD3xCD123, which is being developed as a potential treatment of frontline acute myelogenous leukemia. The company's preclinical candidates, APVO711, CD3xCD123, APVO0442, and APVO603, are being developed using the ADAPTIR modular protein technology platform. The company's versatile and robust ADAPTIR and ADAPTIR-FLEX platforms are designed to generate monospecific, bispecific, and multi-specific antibody candidates that are capable of enhancing the human immune system against cancer cells.
https://www.aptevotherapeutics.comSEC filings for APVO on EDGAR
| Form 4 transaction type | Transactions | Shares | Total value |
|---|---|---|---|
| Option exercise | 22 | 13,084 | |
| Tax withholding / forfeiture | 2 | 562 |
Dollar totals are shown for open-market purchases and sales only. Grants, option exercises, gifts and tax withholding are reported by share count because they are not trades at a market price.
31 Form 4 filings on record, the earliest from Jul 17, 2025, newest first. Filing history page 1 of 2.
| Date | Insider | Transaction | Security | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Zsolt Harsanyi - Director | Option exercise | Common Stock | 400 | - | - | |
| Zsolt Harsanyi - Director | Option exercise | Restricted Stock Unit | 400 | $0.00 | - | |
| Jeffrey G. Lamothe - Officer | Option exercise | Common Stock | 961 | - | - | |
| Jeffrey G. Lamothe - Officer | Option exercise | Restricted Stock Unit | 961 | $0.00 | - | |
| Daphne Taylor - Officer | Option exercise | Common Stock | 638 | - | - | |
| Daphne Taylor - Officer | Option exercise | Restricted Stock Unit | 638 | $0.00 | - | |
| Soyoung Kwon - Officer | Option exercise | Common Stock | 638 | - | - | |
| Soyoung Kwon - Officer | Option exercise | Restricted Stock Unit | 638 | $0.00 | - | |
| Dirk Huebner - Officer | Option exercise | Common Stock | 638 | - | - | |
| Dirk Huebner - Officer | Tax withholding / forfeiture | Common Stock | 156 | $4.07 | $635 | |
| Dirk Huebner - Officer | Option exercise | Restricted Stock Unit | 638 | $0.00 | - | |
| Grady Grant III - Director | Option exercise | Common Stock | 400 | - | - | |
| Grady Grant III - Director | Option exercise | Restricted Stock Unit | 400 | $0.00 | - | |
| Marvin L. White - Officer | Option exercise | Common Stock | 1 | - | - | |
| Marvin L. White - Officer | Option exercise | Common Stock | 1,666 | - | - | |
| Marvin L. White - Officer | Tax withholding / forfeiture | Common Stock | 406 | $4.07 | $2K | |
| Marvin L. White - Officer | Option exercise | Restricted Stock Unit | 1 | $0.00 | - | |
| Marvin L. White - Officer | Option exercise | Restricted Stock Unit | 1,666 | $0.00 | - | |
| Daniel Abdun-Nabi - Director | Option exercise | Common Stock | 400 | - | - | |
| Daniel Abdun-Nabi - Director | Option exercise | Restricted Stock Unit | 400 | $0.00 | - | |
| Barbara Lopez Kunz - Director | Option exercise | Common Stock | 400 | - | - | |
| Barbara Lopez Kunz - Director | Option exercise | Restricted Stock Unit | 400 | $0.00 | - | |
| John Niederhuber - Director | Option exercise | Common Stock | 400 | - | - | |
| John Niederhuber - Director | Option exercise | Restricted Stock Unit | 400 | $0.00 | - | |
| Grady Grant III | Open-market purchase | Common Stock | 13,513 | $26.82 | $20K | |
| Daphne Taylor - Officer | Grant or award | Restricted Stock Unit | 11,500 | $0.00 | - | |
| Daniel Abdun-Nabi | Grant or award | Restricted Stock Unit | 7,200 | $0.00 | - | |
| Marvin L. White - Officer | Grant or award | Restricted Stock Unit | 30,000 | $0.00 | - | |
| Grady Grant III | Grant or award | Restricted Stock Unit | 7,200 | $0.00 | - | |
| Zsolt Harsanyi | Grant or award | Restricted Stock Unit | 7,200 | $0.00 | - | |
| Soyoung Kwon - Officer | Grant or award | Restricted Stock Unit | 11,500 | $0.00 | - | |
| Dirk Huebner - Officer | Grant or award | Restricted Stock Unit | 11,500 | $0.00 | - | |
| Jeffrey G. Lamothe - Officer | Grant or award | Restricted Stock Unit | 17,300 | $0.00 | - | |
| Barbara Lopez Kunz | Grant or award | Restricted Stock Unit | 7,200 | $0.00 | - | |
| John Niederhuber | Grant or award | Restricted Stock Unit | 7,200 | $0.00 | - | |
| Jeffrey G. Lamothe - Officer | Option exercise | Common Stock (post-reverse split May ACTIVE) | 5 | - | - | |
| Jeffrey G. Lamothe - Officer | Option exercise | Restricted Stock Unit | 5 | $0.00 | - | |
| Grady Grant III | Option exercise | Common Stock | 1 | - | - | |
| Grady Grant III | Option exercise | Restricted Stock Unit | 1 | $0.00 | - | |
| Barbara Lopez Kunz | Option exercise | Common Stock | 1 | - | - | |
| Barbara Lopez Kunz | Option exercise | Restricted Stock Unit | 1 | $0.00 | - | |
| John Niederhuber | Option exercise | Common Stock | 1 | - | - | |
| John Niederhuber | Option exercise | Restricted Stock Unit | 1 | $0.00 | - | |
| Daniel Abdun-Nabi | Option exercise | Common Stock | 1 | - | - | |
| Daniel Abdun-Nabi | Option exercise | Restricted Stock Unit | 1 | $0.00 | - | |
| Zsolt Harsanyi | Option exercise | Common Stock | 1 | - | - | |
| Zsolt Harsanyi | Option exercise | Restricted Stock Unit | 1 | $0.00 | - | |
| Daphne Taylor - Officer | Option exercise | Common Stock | 3 | - | - | |
| Daphne Taylor - Officer | Option exercise | Restricted Stock Unit | 3 | $0.00 | - | |
| Marvin L. White - Officer | Option exercise | Common Stock | 10 | - | - | |
| Marvin L. White - Officer | Option exercise | Restricted Stock Unit | 10 | $0.00 | - |
Aptevo Therapeutics Inc. (APVO) had 10 insider filings in the last 90 days, with the most recent on 2026-08-11. The full record for APVO runs to 31 Form 4 filings, the earliest from 2025-07-17. InsiderAlpha tracks every Form 4, Form 144, and 8-K filing in real time.
No insider purchases of APVO were filed in the last 90 days. 1 purchase is on record for this company.
No insider sales of APVO were filed in the last 90 days.
This page tracks APVO Form 4 insider transactions, Form 144 sale notices, and 8-K material event disclosures in one timeline. Annual 10-K and quarterly 10-Q reports live on the company's SEC EDGAR page.
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Every Form 4 below links to the original document on SEC EDGAR, so the numbers on this page can be checked against the filing they came from.
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